Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations [0]
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- Product number
- AF639 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse EphA2 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse EphA2 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human (rh) EphA2 is observed, and less than 1% cross-reactivity with rhEphA1, recombinant mouse (rm) EphA3, rmEphA4, rmEphA6, rmEphA7, rmEphA8, and recombinant rat EphA5 is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
AAA82113
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Brusatol-Mediated Inhibition of c-Myc Increases HIF-1α Degradation and Causes Cell Death in Colorectal Cancer under Hypoxia.
EphA2 and ephrin-A5 are not a receptor-ligand pair in the ocular lens.
Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VE‑cadherin/EphA2/MMP9/MMP2 expression.
Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis.
Capillary defects and exaggerated inflammatory response in the airways of EphA2-deficient mice.
Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin.
Oh ET, Kim CW, Kim HG, Lee JS, Park HJ
Theranostics 2017;7(14):3415-3431
Theranostics 2017;7(14):3415-3431
EphA2 and ephrin-A5 are not a receptor-ligand pair in the ocular lens.
Cheng C, Fowler VM, Gong X
Experimental eye research 2017 Sep;162:9-17
Experimental eye research 2017 Sep;162:9-17
Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VE‑cadherin/EphA2/MMP9/MMP2 expression.
Guo JQ, Zheng QH, Chen H, Chen L, Xu JB, Chen MY, Lu D, Wang ZH, Tong HF, Lin S
International journal of oncology 2014 Sep;45(3):1065-72
International journal of oncology 2014 Sep;45(3):1065-72
Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis.
Irie N, Takada Y, Watanabe Y, Matsuzaki Y, Naruse C, Asano M, Iwakura Y, Suda T, Matsuo K
The Journal of biological chemistry 2009 May 22;284(21):14637-44
The Journal of biological chemistry 2009 May 22;284(21):14637-44
Capillary defects and exaggerated inflammatory response in the airways of EphA2-deficient mice.
Okazaki T, Ni A, Baluk P, Ayeni OA, Kearley J, Coyle AJ, Humbles A, McDonald DM
The American journal of pathology 2009 Jun;174(6):2388-99
The American journal of pathology 2009 Jun;174(6):2388-99
Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin.
Guo H, Miao H, Gerber L, Singh J, Denning MF, Gilliam AC, Wang B
Cancer research 2006 Jul 15;66(14):7050-8
Cancer research 2006 Jul 15;66(14):7050-8
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