APR03954G

antibody from Leading Biology

Targeting: IL9R CD129

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR03954G

Provider

Leading Biology

Product name

IL9R Antibody (Center)

Antibody type

Polyclonal

Description

The protein encoded by this gene is a cytokine receptorthat specifically mediates the biological effects of interleukin 9(IL9). The functional IL9 receptor complex requires this protein aswell as the interleukin 2 receptor, gamma (IL2RG), a common gammasubunit shared by the receptors of many different cytokines. Theligand binding of this receptor leads to the activation of variousJAK kinases and STAT proteins, which connect to different biologicresponses. This gene is located at the pseudoautosomal regions of Xand Y chromosomes. Genetic studies suggested an association of thisgene with the development of asthma. Multiple pseudogenes onchromosome 9, 10, 16, and 18 have been described. Alternativelyspliced transcript variants have been found for this gene.

Reactivity

Human, Mouse

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.