BS60260
antibody from Bioworld Technology, Inc
Targeting: TNNT1
ANM, FLJ98147, MGC104241, NEM5, STNT, TNT, TNTS
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS60260 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Troponin T1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human Troponin T1.
- Description
- Actin is a highly conserved protein that is expressed in all eukaryotic cells and interacts with Myosin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. Troponin facilitates the interaction between Actin and Myosin by binding to calcium. Troponin is made up of at least two subunits, which are divergent in cardiac muscle, fast skeletal muscle and slow skeletal muscle. Structures of skeletal muscle Troponin are composed of Troponin C (the sensor), Troponin I (the regulator) and three Troponin T (the link to the muscle thin filament) proteins, one of which functions as a Tropomyosin-binding protein and is known as Troponin T-SS (Troponin T-Slow Skeletal). Defects in the gene encoding Troponin T-SS are the cause of nemaline myopathy type 5 (NEM5), a form of nemaline myopathy characterized by mild contractures of the shoulders and hips, tremors and respiratory problems that often lead to death. Troponin T-SS is expressed as three isoforms due to alternative splicing events.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of Troponin T1 pAb at 1:500 dilutionLane1:A549 whole cell lysateLane2:sp2/0 whole cell lysateLane3:Rat skeletal muscel tissue lysate