Antibody data
- Antibody Data
- Antigen structure
- References [107]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 19987-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19987-1-AP, RRID:AB_10646429
- Product name
- LDHA-Specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LDHA-Specific antibody (Cat. #19987-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Development of a one-plasmid system to replace the endogenous protein with point mutation for post-translational modification studies.
SIX1 Activation Is Involved in Cell Proliferation, Migration, and Anti-inflammation of Acute Ischemia/Reperfusion Injury in Mice.
Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.
Protective Effects of Hif2 Inhibitor PT-2385 on a Neurological Disorder Induced by Deficiency of Irp2.
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis.
A Novel Integrated Metabolism-Immunity Gene Expression Model Predicts the Prognosis of Lung Adenocarcinoma Patients.
The Role of cAMP-PKA Pathway in Lactate-Induced Intramuscular Triglyceride Accumulation and Mitochondria Content Increase in Mice.
Alpha-Enolase Protects Hepatocyte Against Heat Stress Through Focal Adhesion Kinase-Mediated Phosphatidylinositol 3-Kinase/Akt Pathway.
Qian Yang Yu Yin Granule Improves Renal Injury of Hypertension by Regulating Metabolic Reprogramming Mediated by HIF-1α/PKM2 Positive Feedback Loop.
Biochanin A Inhibits Glioblastoma Growth via Restricting Glycolysis and Mitochondrial Oxidative Phosphorylation.
The Warburg effect as a therapeutic target for bladder cancers and intratumoral heterogeneity in associated molecular targets.
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2.
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue.
2-Deoxy-D-glucose impedes T cell-induced apoptosis of keratinocytes in oral lichen planus.
Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness.
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.
Expression of lactate dehydrogenase A and B isoforms in the mouse kidney.
Long noncoding RNA LINC00518 induces radioresistance by regulating glycolysis through an miR-33a-3p/HIF-1α negative feedback loop in melanoma.
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury by targeting PKM2/HIF-1α axis.
Hypoxia-induced FOXO4/LDHA axis modulates gastric cancer cell glycolysis and progression.
OMA1 reprograms metabolism under hypoxia to promote colorectal cancer development.
Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export.
Short-form RON (sf-RON) enhances glucose metabolism to promote cell proliferation via activating β-catenin/SIX1 signaling pathway in gastric cancer.
Jiedu Sangen decoction inhibits chemoresistance to 5-fluorouracil of colorectal cancer cells by suppressing glycolysis via PI3K/AKT/HIF-1α signaling pathway.
Loss of DSTYK activates Wnt/β-catenin signaling and glycolysis in lung adenocarcinoma.
The deubiquitinase USP38 promotes cell proliferation through stabilizing c-Myc.
STAT3/LINC00671 axis regulates papillary thyroid tumor growth and metastasis via LDHA-mediated glycolysis.
Contribution of Connexin Hemichannels to the Pathogenesis of Acute Lung Injury.
PCK1 Regulates Glycolysis and Tumor Progression in Clear Cell Renal Cell Carcinoma Through LDHA.
Long Noncoding RNA MIR210HG Promotes the Warburg Effect and Tumor Growth by Enhancing HIF-1α Translation in Triple-Negative Breast Cancer.
High fat diet impairs spermatogenesis by regulating glucose and lipid metabolism in Sertoli cells.
ATF4-mediated autophagy-dependent glycolysis plays an important role in attenuating apoptosis induced by Cr (VI) in A549 cells.
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Correlation of hyperpolarized 13 C-MRI data with tissue extract measurements.
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.
All-trans retinoic acid enhances the effect of Fra-1 to inhibit cell proliferation and metabolism in cervical cancer.
Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.
CD38 is involved in cell energy metabolism via activating the PI3K/AKT/mTOR signaling pathway in cervical cancer cells.
HIF1α/PLD2 axis linked to glycolysis induces T-cell immunity in oral lichen planus.
TAB1 regulates glycolysis and activation of macrophages in diabetic nephropathy.
Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer.
Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.
In vivo [U-13C]glucose labeling to assess heart metabolism in murine models of pressure and volume overload.
Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression.
Metabolomic Study on Nude Mice Models of Gastric Cancer Treated with Modified Si Jun Zi Tang via HILIC UHPLC-Q-TOF/MS Analysis.
Proteomic analysis of human periodontal ligament cells under hypoxia.
The KLF14 Transcription Factor Regulates Glycolysis by Downregulating LDHB in Colorectal Cancer.
Recombinant Viral Capsid Protein L2 (rVL2) of HPV 16 Suppresses Cell Proliferation and Glucose Metabolism via ITGB7/C/EBPβ Signaling Pathway in Cervical Cancer Cell Lines.
LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis.
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Accelerated Metabolite Levels of Aerobic Glycolysis and the Pentose Phosphate Pathway Are Required for Efficient Replication of Infectious Spleen and Kidney Necrosis Virus in Chinese Perch Brain Cells.
Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells.
Metabolic adaptation to glycolysis is a basic defense mechanism of macrophages for Mycobacterium tuberculosis infection.
Homeodomain-interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer.
Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPARγ.
p53/Lactate dehydrogenase A axis negatively regulates aerobic glycolysis and tumor progression in breast cancer expressing wild-type p53.
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Type Iγ phosphatidylinositol phosphate kinase promotes tumor growth by facilitating Warburg effect in colorectal cancer.
UHRF1 promotes aerobic glycolysis and proliferation via suppression of SIRT4 in pancreatic cancer.
Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells.
Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF-1α Axis of Breast Cancer Cells.
Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes.
The anti-androgenic effects of cypermethrin mediated by non-classical testosterone pathway activation of mitogen-activated protein kinase cascade in mouse Sertoli cells.
Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21.
Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells.
miR‑199a‑3p/Sp1/LDHA axis controls aerobic glycolysis in testicular tumor cells.
NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death.
Anti-Cancer Effects of Emodin on HepG2 Cells as Revealed by 1H NMR Based Metabolic Profiling.
BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer.
The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1.
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis.
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Detachment from the primary site and suspension in ascites as the initial step in metabolic reprogramming and metastasis to the omentum in ovarian cancer.
RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis.
TCF7L2 positively regulates aerobic glycolysis via the EGLN2/HIF-1α axis and indicates prognosis in pancreatic cancer.
Nalmefene attenuates malignant potential in colorectal cancer cell via inhibition of opioid receptor.
PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules.
GPx1 is involved in the induction of protective autophagy in pancreatic cancer cells in response to glucose deprivation.
Expression and prognostic value of lactate dehydrogenase-A and -D subunits in human uterine myoma and uterine sarcoma.
A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism.
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Mitochondrial toxicity of perfluorooctane sulfonate in mouse embryonic stem cell-derived cardiomyocytes.
ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer.
Copper therapy reduces intravascular hemolysis and derepresses ferroportin in mice with mosaic mutation (Atp7amo-ms): An implication for copper-mediated regulation of the Slc40a1 gene expression.
Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer.
Ischemia/Reperfusion-Induced Translocation of PKCβII to Mitochondria as an Important Mediator of a Protective Signaling Mechanism in an Ischemia-Resistant Region of the Hippocampus.
miR-30a-5p suppresses breast tumor growth and metastasis through inhibition of LDHA-mediated Warburg effect.
Inhibition of mTORC1 signaling sensitizes hepatocellular carcinoma cells to glycolytic stress.
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
Overexpression of ABCC3 promotes cell proliferation, drug resistance, and aerobic glycolysis and is associated with poor prognosis in urinary bladder cancer patients.
The epigenetic regulation of HIF-1α by SIRT1 in MPP(+) treated SH-SY5Y cells.
NKG2D ligand expression in pediatric brain tumors.
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.
MiR-34b-3 and miR-449a inhibit malignant progression of nasopharyngeal carcinoma by targeting lactate dehydrogenase A.
Inhibition of LDHA suppresses tumor progression in prostate cancer.
Alpha-enolase promotes cell glycolysis, growth, migration, and invasion in non-small cell lung cancer through FAK-mediated PI3K/AKT pathway.
Enolase-1 is a therapeutic target in endometrial carcinoma.
The c-Myc-LDHA axis positively regulates aerobic glycolysis and promotes tumor progression in pancreatic cancer.
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.
Ishrat I, Cheng A, Yu F, Guo J, Zhang P, Zhang K, Yang Z
Molecular biology reports 2022 Jan;49(1):1-7
Molecular biology reports 2022 Jan;49(1):1-7
SIX1 Activation Is Involved in Cell Proliferation, Migration, and Anti-inflammation of Acute Ischemia/Reperfusion Injury in Mice.
Jin Y, Zhang M, Li M, Zhang H, Zhao L, Qian C, Li S, Zhang H, Gao M, Pan B, Li R, Wan X, Cao C
Frontiers in molecular biosciences 2021;8:725319
Frontiers in molecular biosciences 2021;8:725319
Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.
Yang K, Wu K, Feng J, Yutian L, Zhu X, Xu D
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5526581
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5526581
Protective Effects of Hif2 Inhibitor PT-2385 on a Neurological Disorder Induced by Deficiency of Irp2.
Shen J, Xu L, Li Y, Dong W, Cai J, Liu Y, Zhao H, Xu T, Holtz EM, Chang Y, Qiao T, Li K
Frontiers in neuroscience 2021;15:715222
Frontiers in neuroscience 2021;15:715222
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Gao M, Yang J, Gong H, Lin Y, Liu J
Frontiers in pharmacology 2021;12:760055
Frontiers in pharmacology 2021;12:760055
Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis.
Chen W, Zhang J, Zhong W, Liu Y, Lu Y, Zeng Z, Huang H, Wan X, Meng X, Zou F, Cai S, Dong H
Frontiers in pharmacology 2021;12:744826
Frontiers in pharmacology 2021;12:744826
A Novel Integrated Metabolism-Immunity Gene Expression Model Predicts the Prognosis of Lung Adenocarcinoma Patients.
Chen S, Duan Y, Wu Y, Yang D, An J
Frontiers in pharmacology 2021;12:728368
Frontiers in pharmacology 2021;12:728368
The Role of cAMP-PKA Pathway in Lactate-Induced Intramuscular Triglyceride Accumulation and Mitochondria Content Increase in Mice.
Chen S, Zhou L, Sun J, Qu Y, Chen M
Frontiers in physiology 2021;12:709135
Frontiers in physiology 2021;12:709135
Alpha-Enolase Protects Hepatocyte Against Heat Stress Through Focal Adhesion Kinase-Mediated Phosphatidylinositol 3-Kinase/Akt Pathway.
Zeng T, Cao Y, Gu T, Chen L, Tian Y, Li G, Shen J, Tao Z, Lu L
Frontiers in genetics 2021;12:693780
Frontiers in genetics 2021;12:693780
Qian Yang Yu Yin Granule Improves Renal Injury of Hypertension by Regulating Metabolic Reprogramming Mediated by HIF-1α/PKM2 Positive Feedback Loop.
Qian L, Ren S, Xu Z, Zheng Y, Wu L, Yang Y, Wang Y, Li J, Yan S, Fang Z
Frontiers in pharmacology 2021;12:667433
Frontiers in pharmacology 2021;12:667433
Biochanin A Inhibits Glioblastoma Growth via Restricting Glycolysis and Mitochondrial Oxidative Phosphorylation.
Dong Q, Li Q, Duan L, Yin H, Wang X, Liu Y, Wang B, Li K, Yao X, Yuan G, Pan Y
Frontiers in oncology 2021;11:652008
Frontiers in oncology 2021;11:652008
The Warburg effect as a therapeutic target for bladder cancers and intratumoral heterogeneity in associated molecular targets.
Burns JE, Hurst CD, Knowles MA, Phillips RM, Allison SJ
Cancer science 2021 Sep;112(9):3822-3834
Cancer science 2021 Sep;112(9):3822-3834
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Jiang M, Li X, Zhang J, Lu Y, Shi Y, Zhu C, Liu Y, Qin B, Luo Z, Du Y, Luo L, Peng L, You J
ACS nano 2021 Sep 28;15(9):14522-14534
ACS nano 2021 Sep 28;15(9):14522-14534
Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2.
Li X, Zhang Y, Wang X, Lin F, Cheng X, Wang Z, Wang X
Cell biology and toxicology 2021 Sep 12;
Cell biology and toxicology 2021 Sep 12;
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Hasenbilige, Mei J, Dlamini MB, Gao Z, Jiang L, Li Q, Geng C, Shi X, Liu Y, Kong Y, Cao J
Toxicology 2021 Oct;462:152928
Toxicology 2021 Oct;462:152928
Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue.
Newton DA, Lottes RG, Ryan RM, Spyropoulos DD, Baatz JE
Respiratory research 2021 Oct 28;22(1):278
Respiratory research 2021 Oct 28;22(1):278
2-Deoxy-D-glucose impedes T cell-induced apoptosis of keratinocytes in oral lichen planus.
Wang F, Zhang J, Zhou G
Journal of cellular and molecular medicine 2021 Nov;25(21):10257-10267
Journal of cellular and molecular medicine 2021 Nov;25(21):10257-10267
Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness.
Li R, Li H, Zhu L, Zhang X, Liu D, Li Q, Ni B, Hu L, Zhang Z, Zhang Y, Wang X, Jiang SH
Cell death & disease 2021 Nov 26;12(12):1106
Cell death & disease 2021 Nov 26;12(12):1106
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Lei Y, Guerra Martinez C, Torres-Odio S, Bell SL, Birdwell CE, Bryant JD, Tong CW, Watson RO, West LC, West AP
Science advances 2021 May;7(22)
Science advances 2021 May;7(22)
ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.
Zhu T, Zheng J, Zhuo W, Pan P, Li M, Zhang W, Zhou H, Gao Y, Li X, Liu Z
Cell death discovery 2021 May 29;7(1):126
Cell death discovery 2021 May 29;7(1):126
Expression of lactate dehydrogenase A and B isoforms in the mouse kidney.
Osis G, Traylor AM, Black LM, Spangler D, George JF, Zarjou A, Verlander JW, Agarwal A
American journal of physiology. Renal physiology 2021 May 1;320(5):F706-F718
American journal of physiology. Renal physiology 2021 May 1;320(5):F706-F718
Long noncoding RNA LINC00518 induces radioresistance by regulating glycolysis through an miR-33a-3p/HIF-1α negative feedback loop in melanoma.
Liu Y, He D, Xiao M, Zhu Y, Zhou J, Cao K
Cell death & disease 2021 Mar 4;12(3):245
Cell death & disease 2021 Mar 4;12(3):245
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Chen X, Li Z, Yong H, Wang W, Wang D, Chu S, Li M, Hou P, Zheng J, Bai J
Cancer letters 2021 Jun 28;508:115-126
Cancer letters 2021 Jun 28;508:115-126
Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury by targeting PKM2/HIF-1α axis.
Pei L, Le Y, Chen H, Feng J, Liu Z, Zhu J, Wang C, Chen L, Dou X, Lu D
Fitoterapia 2021 Jul;152:104922
Fitoterapia 2021 Jul;152:104922
Hypoxia-induced FOXO4/LDHA axis modulates gastric cancer cell glycolysis and progression.
Wang XH, Jiang ZH, Yang HM, Zhang Y, Xu LH
Clinical and translational medicine 2021 Jan;11(1):e279
Clinical and translational medicine 2021 Jan;11(1):e279
OMA1 reprograms metabolism under hypoxia to promote colorectal cancer development.
Wu Z, Zuo M, Zeng L, Cui K, Liu B, Yan C, Chen L, Dong J, Shangguan F, Hu W, He H, Lu B, Song Z
EMBO reports 2021 Jan 7;22(1):e50827
EMBO reports 2021 Jan 7;22(1):e50827
Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export.
Wang K, Huang W, Chen R, Lin P, Zhang T, Ni YF, Li H, Wu J, Sun XX, Geng JJ, Zhu YM, Nan G, Zhang W, Chen X, Zhu P, Bian H, Chen ZN
Cell metabolism 2021 Jan 5;33(1):160-173.e6
Cell metabolism 2021 Jan 5;33(1):160-173.e6
Short-form RON (sf-RON) enhances glucose metabolism to promote cell proliferation via activating β-catenin/SIX1 signaling pathway in gastric cancer.
Wang Z, Yang Y, Hu S, He J, Wu Z, Qi Z, Huang M, Liu R, Lin Y, Tan C, Xu M, Zhang Z
Cell biology and toxicology 2021 Feb;37(1):35-49
Cell biology and toxicology 2021 Feb;37(1):35-49
Jiedu Sangen decoction inhibits chemoresistance to 5-fluorouracil of colorectal cancer cells by suppressing glycolysis via PI3K/AKT/HIF-1α signaling pathway.
Sun LT, Zhang LY, Shan FY, Shen MH, Ruan SM
Chinese journal of natural medicines 2021 Feb;19(2):143-152
Chinese journal of natural medicines 2021 Feb;19(2):143-152
Loss of DSTYK activates Wnt/β-catenin signaling and glycolysis in lung adenocarcinoma.
Zhong C, Chen M, Chen Y, Yao F, Fang W
Cell death & disease 2021 Dec 1;12(12):1122
Cell death & disease 2021 Dec 1;12(12):1122
The deubiquitinase USP38 promotes cell proliferation through stabilizing c-Myc.
Xu Z, Hu H, Fang D, Wang J, Zhao K
The international journal of biochemistry & cell biology 2021 Aug;137:106023
The international journal of biochemistry & cell biology 2021 Aug;137:106023
STAT3/LINC00671 axis regulates papillary thyroid tumor growth and metastasis via LDHA-mediated glycolysis.
Huo N, Cong R, Sun ZJ, Li WC, Zhu X, Xue CY, Chen Z, Ma LY, Chu Z, Han YC, Kang XF, Jia SH, Du N, Kang L, Xu XJ
Cell death & disease 2021 Aug 17;12(9):799
Cell death & disease 2021 Aug 17;12(9):799
Contribution of Connexin Hemichannels to the Pathogenesis of Acute Lung Injury.
Wang S, Sun Y, Bai Y, Zhou N, Chen N, Miller EJ, Zhang Y, Li W
Mediators of inflammation 2020;2020:8094347
Mediators of inflammation 2020;2020:8094347
PCK1 Regulates Glycolysis and Tumor Progression in Clear Cell Renal Cell Carcinoma Through LDHA.
Shi L, An S, Liu Y, Liu J, Wang F
OncoTargets and therapy 2020;13:2613-2627
OncoTargets and therapy 2020;13:2613-2627
Long Noncoding RNA MIR210HG Promotes the Warburg Effect and Tumor Growth by Enhancing HIF-1α Translation in Triple-Negative Breast Cancer.
Du Y, Wei N, Ma R, Jiang SH, Song D
Frontiers in oncology 2020;10:580176
Frontiers in oncology 2020;10:580176
High fat diet impairs spermatogenesis by regulating glucose and lipid metabolism in Sertoli cells.
Luo D, Zhang M, Su X, Liu L, Zhou X, Zhang X, Zheng D, Yu C, Guan Q
Life sciences 2020 Sep 15;257:118028
Life sciences 2020 Sep 15;257:118028
ATF4-mediated autophagy-dependent glycolysis plays an important role in attenuating apoptosis induced by Cr (VI) in A549 cells.
Gao Z, Dlamini MB, Ge H, Jiang L, Geng C, Li Q, Shi X, Liu Y, Cao J
Toxicology letters 2020 Oct 1;331:178-187
Toxicology letters 2020 Oct 1;331:178-187
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Sun Z, Zhang Q, Yuan W, Li X, Chen C, Guo Y, Shao B, Dang Q, Zhou Q, Wang Q, Wang G, Liu J, Kan Q
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250
Correlation of hyperpolarized 13 C-MRI data with tissue extract measurements.
Lee CY, Lau JYC, Geraghty BJ, Chen AP, Gu YP, Cunningham CH
NMR in biomedicine 2020 May;33(5):e4269
NMR in biomedicine 2020 May;33(5):e4269
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.
Li ST, Huang, Shen S, Cai Y, Xing S, Wu G, Jiang Z, Hao Y, Yuan M, Wang N, Zhu L, Yan R, Yang D, Wang L, Liu Z, Hu X, Zhou R, Qu K, Li A, Duan X, Zhang H, Gao P
Nature metabolism 2020 Mar;2(3):256-269
Nature metabolism 2020 Mar;2(3):256-269
All-trans retinoic acid enhances the effect of Fra-1 to inhibit cell proliferation and metabolism in cervical cancer.
Dou Y, Huang D, Zeng X, Zhou Y, Jiang X, Yue C, He J, Xiao S
Biotechnology letters 2020 Jun;42(6):1051-1060
Biotechnology letters 2020 Jun;42(6):1051-1060
Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.
Wang C, Li Y, Yan S, Wang H, Shao X, Xiao M, Yang B, Qin G, Kong R, Chen R, Zhang N
Nature communications 2020 Jun 22;11(1):3162
Nature communications 2020 Jun 22;11(1):3162
CD38 is involved in cell energy metabolism via activating the PI3K/AKT/mTOR signaling pathway in cervical cancer cells.
Liao S, Liang L, Yue C, He J, He Z, Jin X, Luo G, Zhou Y
International journal of oncology 2020 Jul;57(1):338-354
International journal of oncology 2020 Jul;57(1):338-354
HIF1α/PLD2 axis linked to glycolysis induces T-cell immunity in oral lichen planus.
Wang F, Zhang J, Zhou G
Biochimica et biophysica acta. General subjects 2020 Jul;1864(7):129602
Biochimica et biophysica acta. General subjects 2020 Jul;1864(7):129602
TAB1 regulates glycolysis and activation of macrophages in diabetic nephropathy.
Zeng H, Qi X, Xu X, Wu Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2020 Dec;69(12):1215-1234
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2020 Dec;69(12):1215-1234
Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer.
Deng X, Zhao J, Qu L, Duan Z, Fu R, Zhu C, Fan D
Biochemical pharmacology 2020 Aug;178:114038
Biochemical pharmacology 2020 Aug;178:114038
Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.
Dong D, Dong Y, Fu J, Lu S, Yuan C, Xia M, Sun L
Life sciences 2020 Aug 15;255:117846
Life sciences 2020 Aug 15;255:117846
In vivo [U-13C]glucose labeling to assess heart metabolism in murine models of pressure and volume overload.
Schnelle M, Chong M, Zoccarato A, Elkenani M, Sawyer GJ, Hasenfuss G, Ludwig C, Shah AM
American journal of physiology. Heart and circulatory physiology 2020 Aug 1;319(2):H422-H431
American journal of physiology. Heart and circulatory physiology 2020 Aug 1;319(2):H422-H431
Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression.
Weng ML, Chen WK, Chen XY, Lu H, Sun ZR, Yu Q, Sun PF, Xu YJ, Zhu MM, Jiang N, Zhang J, Zhang JP, Song YL, Ma D, Zhang XP, Miao CH
Nature communications 2020 Apr 20;11(1):1869
Nature communications 2020 Apr 20;11(1):1869
Metabolomic Study on Nude Mice Models of Gastric Cancer Treated with Modified Si Jun Zi Tang via HILIC UHPLC-Q-TOF/MS Analysis.
Nie S, Zhao Y, Qiu X, Wang W, Yao Y, Yi M, Wang D
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3817879
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3817879
Proteomic analysis of human periodontal ligament cells under hypoxia.
Li Q, Luo T, Lu W, Yi X, Zhao Z, Liu J
Proteome science 2019;17:3
Proteome science 2019;17:3
The KLF14 Transcription Factor Regulates Glycolysis by Downregulating LDHB in Colorectal Cancer.
Wu G, Yuan S, Chen Z, Chen G, Fan Q, Dong H, Ye F, Li J, Zhu X
International journal of biological sciences 2019;15(3):628-635
International journal of biological sciences 2019;15(3):628-635
Recombinant Viral Capsid Protein L2 (rVL2) of HPV 16 Suppresses Cell Proliferation and Glucose Metabolism via ITGB7/C/EBPβ Signaling Pathway in Cervical Cancer Cell Lines.
Chai Z, Yang Y, Gu Z, Cai X, Ye W, Kong L, Qiu X, Ying L, Wang Z, Wang L
OncoTargets and therapy 2019;12:10415-10425
OncoTargets and therapy 2019;12:10415-10425
LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis.
Hua Q, Jin M, Mi B, Xu F, Li T, Zhao L, Liu J, Huang G
Journal of hematology & oncology 2019 Sep 5;12(1):91
Journal of hematology & oncology 2019 Sep 5;12(1):91
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Zhao H, Wu S, Li H, Duan Q, Zhang Z, Shen Q, Wang C, Yin T
Molecular therapy oncolytics 2019 Sep 27;14:299-312
Molecular therapy oncolytics 2019 Sep 27;14:299-312
Accelerated Metabolite Levels of Aerobic Glycolysis and the Pentose Phosphate Pathway Are Required for Efficient Replication of Infectious Spleen and Kidney Necrosis Virus in Chinese Perch Brain Cells.
Guo X, Wu S, Li N, Lin Q, Liu L, Liang H, Niu Y, Huang Z, Fu X
Biomolecules 2019 Sep 2;9(9)
Biomolecules 2019 Sep 2;9(9)
Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells.
Chen L, Cheng X, Tu W, Qi Z, Li H, Liu F, Yang Y, Zhang Z, Wang Z
Cellular oncology (Dordrecht) 2019 Oct;42(5):679-690
Cellular oncology (Dordrecht) 2019 Oct;42(5):679-690
Metabolic adaptation to glycolysis is a basic defense mechanism of macrophages for Mycobacterium tuberculosis infection.
Osada-Oka M, Goda N, Saiga H, Yamamoto M, Takeda K, Ozeki Y, Yamaguchi T, Soga T, Tateishi Y, Miura K, Okuzaki D, Kobayashi K, Matsumoto S
International immunology 2019 Nov 8;31(12):781-793
International immunology 2019 Nov 8;31(12):781-793
Homeodomain-interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer.
Qin Y, Hu Q, Ji S, Xu J, Dai W, Liu W, Xu W, Sun Q, Zhang Z, Ni Q, Yu X, Zhang B, Xu X
Cell proliferation 2019 May;52(3):e12603
Cell proliferation 2019 May;52(3):e12603
Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPARγ.
Zhang W, Shao W, Dong Z, Zhang S, Liu C, Chen S
Cell death & disease 2019 May 28;10(6):404
Cell death & disease 2019 May 28;10(6):404
p53/Lactate dehydrogenase A axis negatively regulates aerobic glycolysis and tumor progression in breast cancer expressing wild-type p53.
Zhou Y, Niu W, Luo Y, Li H, Xie Y, Wang H, Liu Y, Fan S, Li Z, Xiong W, Li X, Ren C, Tan M, Li G, Zhou M
Cancer science 2019 Mar;110(3):939-949
Cancer science 2019 Mar;110(3):939-949
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Ma B, Cheng H, Mu C, Geng G, Zhao T, Luo Q, Ma K, Chang R, Liu Q, Gao R, Nie J, Xie J, Han J, Chen L, Ma G, Zhu Y, Chen Q
Nature communications 2019 Mar 4;10(1):1034
Nature communications 2019 Mar 4;10(1):1034
Type Iγ phosphatidylinositol phosphate kinase promotes tumor growth by facilitating Warburg effect in colorectal cancer.
Peng W, Huang W, Ge X, Xue L, Zhao W, Xue J
EBioMedicine 2019 Jun;44:375-386
EBioMedicine 2019 Jun;44:375-386
UHRF1 promotes aerobic glycolysis and proliferation via suppression of SIRT4 in pancreatic cancer.
Hu Q, Qin Y, Ji S, Xu W, Liu W, Sun Q, Zhang Z, Liu M, Ni Q, Yu X, Xu X
Cancer letters 2019 Jun 28;452:226-236
Cancer letters 2019 Jun 28;452:226-236
Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells.
Wang F, Jia Y, Li M, Wang L, Shao J, Guo Q, Tan S, Ding H, Chen A, Zhang F, Zheng S
Cell communication and signaling : CCS 2019 Feb 11;17(1):11
Cell communication and signaling : CCS 2019 Feb 11;17(1):11
Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF-1α Axis of Breast Cancer Cells.
Chai XX, Le YF, Wang JC, Mei CX, Feng JF, Zhao H, Wang C, Lu DZ
Journal of food science 2019 Dec;84(12):3825-3832
Journal of food science 2019 Dec;84(12):3825-3832
Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes.
Paul BT, Tesfay L, Winkler CR, Torti FM, Torti SV
Scientific reports 2019 Dec 23;9(1):19634
Scientific reports 2019 Dec 23;9(1):19634
The anti-androgenic effects of cypermethrin mediated by non-classical testosterone pathway activation of mitogen-activated protein kinase cascade in mouse Sertoli cells.
Wang Q, Wang HX, Shen JY, Zhang R, Hong JW, Li Z, Chen G, Li MX, Ding Z, Li J, Zhang JP, Zhang MR, Xu LC
Ecotoxicology and environmental safety 2019 Aug 15;177:58-65
Ecotoxicology and environmental safety 2019 Aug 15;177:58-65
Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21.
Yan B, Cheng L, Jiang Z, Chen K, Zhou C, Sun L, Cao J, Qian W, Li J, Shan T, Lei J, Ma Q, Ma J
Oxidative medicine and cellular longevity 2018;2018:1346958
Oxidative medicine and cellular longevity 2018;2018:1346958
Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells.
Yang Y, Cao Y, Chen L, Liu F, Qi Z, Cheng X, Wang Z
Cancer medicine 2018 Sep;7(9):4610-4618
Cancer medicine 2018 Sep;7(9):4610-4618
miR‑199a‑3p/Sp1/LDHA axis controls aerobic glycolysis in testicular tumor cells.
Zhou S, Min Z, Sun K, Qu S, Zhou J, Duan H, Liu H, Liu X, Gong Z, Li D
International journal of molecular medicine 2018 Oct;42(4):2163-2174
International journal of molecular medicine 2018 Oct;42(4):2163-2174
NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death.
Huang D, Chen J, Yang L, Ouyang Q, Li J, Lao L, Zhao J, Liu J, Lu Y, Xing Y, Chen F, Su F, Yao H, Liu Q, Su S, Song E
Nature immunology 2018 Oct;19(10):1112-1125
Nature immunology 2018 Oct;19(10):1112-1125
Anti-Cancer Effects of Emodin on HepG2 Cells as Revealed by 1H NMR Based Metabolic Profiling.
Xing YX, Li MH, Tao L, Ruan LY, Hong W, Chen C, Zhao WL, Xu H, Chen JF, Wang JS
Journal of proteome research 2018 May 4;17(5):1943-1952
Journal of proteome research 2018 May 4;17(5):1943-1952
BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer.
Niu W, Luo Y, Wang X, Zhou Y, Li H, Wang H, Fu Y, Liu S, Yin S, Li J, Zhao R, Liu Y, Fan S, Li Z, Xiong W, Li X, Li G, Ren C, Tan M, Zhou M
Cell death & disease 2018 May 1;9(5):519
Cell death & disease 2018 May 1;9(5):519
The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1.
Zhao Y, Liu Y, Lin L, Huang Q, He W, Zhang S, Dong S, Wen Z, Rao J, Liao W, Shi M
Molecular cancer 2018 Mar 6;17(1):69
Molecular cancer 2018 Mar 6;17(1):69
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Li L, Liang Y, Kang L, Liu Y, Gao S, Chen S, Li Y, You W, Dong Q, Hong T, Yan Z, Jin S, Wang T, Zhao W, Mai H, Huang J, Han X, Ji Q, Song Q, Yang C, Zhao S, Xu X, Ye Q
Cancer cell 2018 Mar 12;33(3):368-385.e7
Cancer cell 2018 Mar 12;33(3):368-385.e7
Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis.
Li Q, Li Y, Liang L, Li J, Luo D, Liu Q, Cai S, Li X
Cell communication and signaling : CCS 2018 Jun 8;16(1):26
Cell communication and signaling : CCS 2018 Jun 8;16(1):26
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Wang S, Li J, Xie J, Liu F, Duan Y, Wu Y, Huang S, He X, Wang Z, Wu X
Oncogene 2018 Jul;37(30):4164-4180
Oncogene 2018 Jul;37(30):4164-4180
Detachment from the primary site and suspension in ascites as the initial step in metabolic reprogramming and metastasis to the omentum in ovarian cancer.
Sato M, Kawana K, Adachi K, Fujimoto A, Yoshida M, Nakamura H, Nishida H, Inoue T, Taguchi A, Ogishima J, Eguchi S, Yamashita A, Tomio K, Komatsu A, Wada-Hiraike O, Oda K, Nagamatsu T, Osuga Y, Fujii T
Oncology letters 2018 Jan;15(1):1357-1361
Oncology letters 2018 Jan;15(1):1357-1361
RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis.
Yang Z, Wang Y, Zhang Y, He X, Zhong CQ, Ni H, Chen X, Liang Y, Wu J, Zhao S, Zhou D, Han J
Nature cell biology 2018 Feb;20(2):186-197
Nature cell biology 2018 Feb;20(2):186-197
TCF7L2 positively regulates aerobic glycolysis via the EGLN2/HIF-1α axis and indicates prognosis in pancreatic cancer.
Xiang J, Hu Q, Qin Y, Ji S, Xu W, Liu W, Shi S, Liang C, Liu J, Meng Q, Liang D, Ni Q, Xu J, Zhang B, Yu X
Cell death & disease 2018 Feb 23;9(3):321
Cell death & disease 2018 Feb 23;9(3):321
Nalmefene attenuates malignant potential in colorectal cancer cell via inhibition of opioid receptor.
Wu Q, Chen X, Wang J, Sun P, Weng M, Chen W, Sun Z, Zhu M, Miao C
Acta biochimica et biophysica Sinica 2018 Feb 1;50(2):156-163
Acta biochimica et biophysica Sinica 2018 Feb 1;50(2):156-163
PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules.
Lyu Z, Mao Z, Li Q, Xia Y, Liu Y, He Q, Wang Y, Zhao H, Lu Z, Zhou Q
EBioMedicine 2018 Dec;38:178-190
EBioMedicine 2018 Dec;38:178-190
GPx1 is involved in the induction of protective autophagy in pancreatic cancer cells in response to glucose deprivation.
Meng Q, Xu J, Liang C, Liu J, Hua J, Zhang Y, Ni Q, Shi S, Yu X
Cell death & disease 2018 Dec 11;9(12):1187
Cell death & disease 2018 Dec 11;9(12):1187
Expression and prognostic value of lactate dehydrogenase-A and -D subunits in human uterine myoma and uterine sarcoma.
Song KJ, Yu XN, Lv T, Chen YL, Diao YC, Liu SL, Wang YK, Yao Q
Medicine 2018 Apr;97(14):e0268
Medicine 2018 Apr;97(14):e0268
A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism.
Liu W, Zhang B, Hu Q, Qin Y, Xu W, Shi S, Liang C, Meng Q, Xiang J, Liang D, Ji S, Liu J, Hu P, Liu L, Liu C, Long J, Ni Q, Yu X, Xu J
International journal of oncology 2017 May;50(5):1792-1800
International journal of oncology 2017 May;50(5):1792-1800
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, Hu L, Tian S, Wu M, Hui L, Zhang H, Gao P
The EMBO journal 2017 May 15;36(10):1330-1347
The EMBO journal 2017 May 15;36(10):1330-1347
Mitochondrial toxicity of perfluorooctane sulfonate in mouse embryonic stem cell-derived cardiomyocytes.
Tang LL, Wang JD, Xu TT, Zhao Z, Zheng JJ, Ge RS, Zhu DY
Toxicology 2017 May 1;382:108-116
Toxicology 2017 May 1;382:108-116
ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer.
Liang C, Qin Y, Zhang B, Ji S, Shi S, Xu W, Liu J, Xiang J, Liang D, Hu Q, Ni Q, Yu X, Xu J
Cancer letters 2017 Mar 1;388:303-311
Cancer letters 2017 Mar 1;388:303-311
Copper therapy reduces intravascular hemolysis and derepresses ferroportin in mice with mosaic mutation (Atp7amo-ms): An implication for copper-mediated regulation of the Slc40a1 gene expression.
Lenartowicz M, Starzyński RR, Jończy A, Staroń R, Antoniuk J, Krzeptowski W, Grzmil P, Bednarz A, Pierzchała O, Ogórek M, Rajfur Z, Baster Z, Lipiński P
Biochimica et biophysica acta. Molecular basis of disease 2017 Jun;1863(6):1410-1421
Biochimica et biophysica acta. Molecular basis of disease 2017 Jun;1863(6):1410-1421
Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer.
Cai X, Ding H, Liu Y, Pan G, Li Q, Yang Z, Liu W
Acta biochimica et biophysica Sinica 2017 Feb 6;49(2):119-127
Acta biochimica et biophysica Sinica 2017 Feb 6;49(2):119-127
Ischemia/Reperfusion-Induced Translocation of PKCβII to Mitochondria as an Important Mediator of a Protective Signaling Mechanism in an Ischemia-Resistant Region of the Hippocampus.
Krupska O, Sarnowska A, Fedorczyk B, Gewartowska M, Misicka A, Zablocka B, Beresewicz M
Neurochemical research 2017 Aug;42(8):2392-2403
Neurochemical research 2017 Aug;42(8):2392-2403
miR-30a-5p suppresses breast tumor growth and metastasis through inhibition of LDHA-mediated Warburg effect.
Li L, Kang L, Zhao W, Feng Y, Liu W, Wang T, Mai H, Huang J, Chen S, Liang Y, Han J, Xu X, Ye Q
Cancer letters 2017 Aug 1;400:89-98
Cancer letters 2017 Aug 1;400:89-98
Inhibition of mTORC1 signaling sensitizes hepatocellular carcinoma cells to glycolytic stress.
Zhao X, Jiang P, Deng X, Li Z, Tian F, Guo F, Li X, Wang S
American journal of cancer research 2016;6(10):2289-2298
American journal of cancer research 2016;6(10):2289-2298
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
Li P, Zhang D, Shen L, Dong K, Wu M, Ou Z, Shi D
Scientific reports 2016 Mar 9;6:22831
Scientific reports 2016 Mar 9;6:22831
Overexpression of ABCC3 promotes cell proliferation, drug resistance, and aerobic glycolysis and is associated with poor prognosis in urinary bladder cancer patients.
Liu X, Yao D, Liu C, Cao Y, Yang Q, Sun Z, Liu D
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):8367-74
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):8367-74
The epigenetic regulation of HIF-1α by SIRT1 in MPP(+) treated SH-SY5Y cells.
Dong SY, Guo YJ, Feng Y, Cui XX, Kuo SH, Liu T, Wu YC
Biochemical and biophysical research communications 2016 Feb 5;470(2):453-459
Biochemical and biophysical research communications 2016 Feb 5;470(2):453-459
NKG2D ligand expression in pediatric brain tumors.
Haberthur K, Brennan K, Hoglund V, Balcaitis S, Chinn H, Davis A, Kreuser S, Winter C, Leary SE, Deutsch GH, Ellenbogen RG, Crane CA
Cancer biology & therapy 2016 Dec;17(12):1253-1265
Cancer biology & therapy 2016 Dec;17(12):1253-1265
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
Dong K, Wu M, Liu X, Huang Y, Zhang D, Wang Y, Yan LJ, Shi D
Free radical biology & medicine 2016 Dec;101:334-347
Free radical biology & medicine 2016 Dec;101:334-347
ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.
Dong K, Ni H, Wu M, Tang Z, Halim M, Shi D
Biochemical and biophysical research communications 2016 Aug 5;476(4):204-211
Biochemical and biophysical research communications 2016 Aug 5;476(4):204-211
MiR-34b-3 and miR-449a inhibit malignant progression of nasopharyngeal carcinoma by targeting lactate dehydrogenase A.
Li H, Li X, Ge X, Jia L, Zhang Z, Fang R, Yang J, Liu J, Peng S, Zhou M, Xiang J, Zeng Z, Zhou W, Xiong W, Xiao G, Fang L, Li GY, Li Z
Oncotarget 2016 Aug 23;7(34):54838-54851
Oncotarget 2016 Aug 23;7(34):54838-54851
Inhibition of LDHA suppresses tumor progression in prostate cancer.
Xian ZY, Liu JM, Chen QK, Chen HZ, Ye CJ, Xue J, Yang HQ, Li JL, Liu XF, Kuang SJ
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Sep;36(10):8093-100
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Sep;36(10):8093-100
Alpha-enolase promotes cell glycolysis, growth, migration, and invasion in non-small cell lung cancer through FAK-mediated PI3K/AKT pathway.
Fu QF, Liu Y, Fan Y, Hua SN, Qu HY, Dong SW, Li RL, Zhao MY, Zhen Y, Yu XL, Chen YY, Luo RC, Li R, Li LB, Deng XJ, Fang WY, Liu Z, Song X
Journal of hematology & oncology 2015 Mar 8;8:22
Journal of hematology & oncology 2015 Mar 8;8:22
Enolase-1 is a therapeutic target in endometrial carcinoma.
Zhao M, Fang W, Wang Y, Guo S, Shu L, Wang L, Chen Y, Fu Q, Liu Y, Hua S, Fan Y, Liu Y, Deng X, Luo R, Mei Z, Jiang Q, Liu Z
Oncotarget 2015 Jun 20;6(17):15610-27
Oncotarget 2015 Jun 20;6(17):15610-27
The c-Myc-LDHA axis positively regulates aerobic glycolysis and promotes tumor progression in pancreatic cancer.
He TL, Zhang YJ, Jiang H, Li XH, Zhu H, Zheng KL
Medical oncology (Northwood, London, England) 2015 Jul;32(7):187
Medical oncology (Northwood, London, England) 2015 Jul;32(7):187
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Sun L, Song L, Wan Q, Wu G, Li X, Wang Y, Wang J, Liu Z, Zhong X, He X, Shen S, Pan X, Li A, Wang Y, Gao P, Tang H, Zhang H
Cell research 2015 Apr;25(4):429-44
Cell research 2015 Apr;25(4):429-44
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.
Ma X, Li C, Sun L, Huang D, Li T, He X, Wu G, Yang Z, Zhong X, Song L, Gao P, Zhang H
Nature communications 2014 Oct 10;5:5212
Nature communications 2014 Oct 10;5:5212
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 19987-1-AP(LDHA-Specific antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells using 19987-1-AP( LDHA-Specific Antibody) at dilution of 1:100 and Rhodamine-Goat anti-Rabbit IgG
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 19987-1-AP(LDHA-Specific antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 19987-1-AP(LDHA-Specific antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LDHA-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human LDHA-Specific. This antibody recognizes human, mouse, rat antigen. The LDHA-Specific antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.