26469-1-AP

antibody from Proteintech Group

Targeting: SLC25A37 HT015, MFRN, MFRN1, MSCP

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

26469-1-AP

Provider

Proteintech Group

Product name

Mitoferrin 1 antibody

Antibody type

Polyclonal

Description

Mitoferrin 1 antibody (Cat. #26469-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Succinylation modification on NFS1 ameliorates the glucose starvation-induced ferroptosis through maintaining mitochondrial iron homeostasis in oral squamous cell carcinoma cells.

Ling H, Qing L, Zuo L, Wang H, Cai X, Liu Y, Tian H
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 23;1872(6):168276

---

BDH2-driven lysosome-to-mitochondria iron transfer shapes ferroptosis vulnerability of the melanoma cell states.

Rizzollo F, Escamilla-Ayala A, Fattorelli N, Lysiak NB, More S, Hernández Varas P, Barazzuol L, Van den Haute C, Van Asselberghs J, Nittner D, Coene J, Venkataramani V, Michalke B, Gaillet C, Cañeque T, Davidson I, Verhelst SHL, Vangheluwe P, Calì T, Marine JC, Rodriguez R, Bonnereau J, Agostinis P
Nature metabolism 2025 Sep;7(9):1851-1870

---

Mitochondria-localized MBD2c facilitates mtDNA transcription and drug resistance.

Hao Y, Zhou Z, Liu R, Shen S, Liu H, Zhou Y, Sun Y, Mao Q, Zhang T, Li ST, Liu Z, Chu Y, Sun L, Gao P, Zhang H
Nature chemical biology 2025 Jun;21(6):926-938

---

The roles and mechanisms of CDGSH iron-sulfur domain 1 in kainic acid-induced mitochondrial iron overload, dysfunction and neuronal damage.

Wang J, Li S, Xu H, Xue J, Wan X, Wu W, Huang J, Zhang H, Qin Z, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jun;187:118067

---

Ferroptosis triggers mitochondrial fragmentation via Drp1 activation.

Pedrera L, Prieto Clemente L, Dahlhaus A, Lotfipour Nasudivar S, Tishina S, Olmo González D, Stroh J, Yapici FI, Singh RP, Grotehans N, Langer T, García-Sáez AJ, von Karstedt S
Cell death & disease 2025 Jan 25;16(1):40

---

PINK1-deficiency facilitates mitochondrial iron accumulation and colon tumorigenesis.

Arcos M, Goodla L, Kim H, Desai SP, Liu R, Yin K, Liu Z, Martin DR, Xue X
Autophagy 2025 Apr;21(4):737-753

---

Gallium Uncouples Iron Metabolism to Enhance Glioblastoma Radiosensitivity.

Owusu SB, Zaher A, Ahenkorah S, Pandya DN, Wadas TJ, Petronek MS
International journal of molecular sciences 2024 Sep 18;25(18)

---

Imbalance of redox homeostasis and altered cellular signaling induced by the metal complexes of terpyridine.

Malarz K, Ziola P, Zych D, Rurka P, Mrozek-Wilczkiewicz A
Scientific reports 2024 Nov 6;14(1):26951

---

Mitoferrin2 is a synthetic lethal target for chromosome 8p deleted cancers.

Krieg S, Rohde T, Rausch T, Butthof L, Wendler-Link L, Eckert C, Breuhahn K, Galy B, Korbel J, Billmann M, Breinig M, Tschaharganeh DF
Genome medicine 2024 Jun 17;16(1):83

---

Cell density impacts the susceptibility to ferroptosis by modulating IRP1-mediated iron homeostasis.

Yan HF, Tuo QZ, Lei P
Journal of neurochemistry 2024 Jul;168(7):1359-1373

---

Single-cell RNA profiling reveals classification and characteristics of mononuclear phagocytes in colorectal cancer.

Ji T, Fu H, Wang L, Chen J, Tian S, Wang G, Wang L, Wang Z
PLoS genetics 2024 Feb;20(2):e1011176

---

Dual regulation of SLC25A39 by AFG3L2 and iron controls mitochondrial glutathione homeostasis.

Shi X, DeCiucis M, Grabinska KA, Kanyo J, Liu A, Lam TT, Shen H
Molecular cell 2024 Feb 15;84(4):802-810.e6

---

Ginsenoside compound K alleviates brain aging by inhibiting ferroptosis through modulation of the ASK1-MKK7-JNK signaling pathway.

Yan X, Bai X, Sun G, Duan Z, Fu R, Zeng W, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156239

---

Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.

Wang M, Tang J, Zhang S, Pang K, Zhao Y, Liu N, Huang J, Kang J, Dong S, Li H, Tian Z, Duan B, Lu F, Zhang W
Cell death discovery 2023 Oct 24;9(1):394

---

FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway.

Shi L, Tao Z, Zheng L, Yang J, Hu X, Scott K, de Kloet A, Krause E, Collins JF, Cheng Z
Redox biology 2023 Jul;63:102727

---

Contemporary Antiretroviral Therapy Dysregulates Iron Transport and Augments Mitochondrial Dysfunction in HIV-Infected Human Microglia and Neural-Lineage Cells.

Kaur H, Minchella P, Alvarez-Carbonell D, Purandare N, Nagampalli VK, Blankenberg D, Hulgan T, Gerschenson M, Karn J, Aras S, Kallianpur AR
International journal of molecular sciences 2023 Jul 31;24(15)

---

Mitoferrin-1 Promotes Proliferation and Abrogates Protein Oxidation via the Glutathione Pathway in Glioblastoma.

Ali MY, Griguer CE, Flor S, Oliva CR
Antioxidants (Basel, Switzerland) 2023 Feb 1;12(2)

---

Mitochondrial ferritin alleviates apoptosis by enhancing mitochondrial bioenergetics and stimulating glucose metabolism in cerebral ischemia reperfusion.

Wang P, Cui Y, Liu Y, Li Z, Bai H, Zhao Y, Chang YZ
Redox biology 2022 Nov;57:102475

---

ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.

Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li ST, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H
Nature cancer 2022 Jan;3(1):75-89

---

Mitochondrion-mediated iron accumulation promotes carcinogenesis and Warburg effect through reactive oxygen species in osteosarcoma.

Ni S, Kuang Y, Yuan Y, Yu B
Cancer cell international 2020;20:399

---

MiR-7 mediates mitochondrial impairment to trigger apoptosis and necroptosis in Rhabdomyosarcoma.

Yang L, Kong D, He M, Gong J, Nie Y, Tai S, Teng CB
Biochimica et biophysica acta. Molecular cell research 2020 Dec;1867(12):118826

---

Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis.

Maio N, Kim KS, Holmes-Hampton G, Singh A, Rouault TA
Haematologica 2019 Sep;104(9):1756-1767