Antibody data
- Antibody Data
- Antigen structure
- References [101]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 15513-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15513-1-AP, RRID:AB_2206563
- Product name
- Cardiac Troponin T antibody
- Antibody type
- Polyclonal
- Description
- Cardiac Troponin T antibody (Cat. #15513-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Screening and Identification of BMP5 as a Key Regulatory Gene for hPSCs Transcardiomyocyte Differentiation.
Galangin 3-methyl ether alleviates mouse hypertrophic cardiomyopathy via targeting HDAC2 and subsequently inactivating the PI3K-AKT signaling pathway.
Lithospermic Acid Improves Doxorubicin-Induced Cardiomyopathy Through Sirtuin-3-Mediated Deacetylation of p53.
Sustained release of dual p38 inhibitors via supramolecular hydrogels to enhance cardiac repair after MI/R injury.
Development of low-cost electrical stimulation device to promote hiPSC-CM differentiation and functionality.
Ginkgolic acid ameliorates pressure overload-induced cardiac remodeling by inhibiting SAE1 and activating the NRF2/HMOX1 pathway.
Tissue-engineered cardiac patches enriched with IGF1 modified mRNA alleviate myocardial infarction by enhancing cell survival and angiogenesis.
Left bundle branch vs biventricular pacing: mechanistic insights from a canine model.
Imperatorin's Effect on Myocardial Infarction Based on Network Pharmacology and Molecular Docking.
Screening and characterization of natural extracts as dual-functional regulators for cardiomyocyte regeneration and cardiac repair.
Herb pair of Astragali Radix-Descurainiae Semen attenuate heart failure through the myosin VI-Tom1 complex mediated autophagy.
NMDA-Type Glutamate Receptor Activation Promotes Ischemic Arrhythmias by Targeting the AKT1-TBX3-Nav1.5 Axis.
Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis-Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis.
Rab26-mediated lysosomal translocation of eEF1A alleviates myocardial hypertrophy and cardiac remodeling.
Mapping cardiac drug transport: In vitro assessment of cardiac P-glycoprotein function with [(18)F]MC225 by using µ-engineered heart tissues.
HAND1 level controls the specification of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells.
Myocardial delivery of miR30d with peptide-functionalized milk-derived extracellular vesicles for targeted treatment of hypertrophic heart failure.
LncRNA NAV2-AS2 is critical for fibroblast-to-myofibroblast transition and cardiac fibrosis.
Inhibition of ULK1 attenuates ferroptosis-mediated cardiac hypertrophy via HMGA2/METTL14/SLC7A11 axis in mice.
Cathepsin K inhibition promotes efficient differentiation of human embryonic stem cells to mature cardiomyocytes by mediating glucolipid metabolism and cellular energy homeostasis.
Inhibition of circALPK2 enhances proliferation and therapeutic potential of human pluripotent stem cell-derived cardiomyocytes in myocardial infarction.
Multi-stage cooperative ROS-responsive hydrogel platform for drug delivery in myocardial ischemia-reperfusion injury repair.
Skeletal Muscle Alterations in Different Phenotypes of Heart Failure with Preserved Ejection Fraction.
Natural product library screening identifies Darutigenol for the treatment of myocardial infarction and ischemia/reperfusion injury.
Nuclear Receptor ERRγ Protects Against Cardiac Ischemic Injury by Suppressing GBP5-Mediated Myocardial Inflammation.
Single-nuclei multiomics analysis identifies abnormal cardiomyocytes in a murine model of cardiac development.
Pannexin1 via P2rx7/amphiregulin contributes to cardiac fibrosis post myocardial infarction.
Nicotinamide riboside promoted cardiac energetics and alleviated doxorubicin-induced cardiotoxicity via SIRT1/ERRα signal in human pluripotent stem cells-derived cardiomyocytes.
N-Cadherin promotes cardiac regeneration by potentiating pro-mitotic β-Catenin signaling in cardiomyocytes.
Generation and characterization of the LINC01405 knockout human embryonic stem cell line.
MiR-133b-3p attenuates angiotensin II-induced cardiac hypertrophy through the inhibition of apoptosis by targeting CDIP1.
Nynrin enhances cardiac function by inhibiting mitochondrial permeability transition pore opening upon myocardial ischemia/reperfusion injury.
Targeting long-chain acylcarnitine accumulation to protect cardiac mitochondrial homeostasis after complete revascularization.
Y4 RNA fragment alleviates myocardial injury in heart transplantation via SNRNP200 to enhance IL-10 mRNA splicing.
Whole genome transcriptomics reveal distinct atrial versus ventricular responses to neonatal hyperoxia.
Immune-checkpoint-inhibitor therapy directed against PD-L1 is tolerated in the heart without manifestation of cardiac inflammation in a preclinical reversible melanoma mouse model.
Gene Expression, Morphology, and Electrophysiology During the Dynamic Development of Human Induced Pluripotent Stem Cell-Derived Atrial- and Ventricular-Like Cardiomyocytes.
Characterization of the m(6)A regulators' landscape highlights the clinical significance of acute myocardial infarction.
Leukocyte infiltration and cross-talk with cardiomyocytes exploit intracellular stress pathways in dilated cardiomyopathy of idiopathic origin.
Colchicine prevents perioperative myocardial injury in cardiac surgery by inhibiting the formation of neutrophil extracellular traps: evidence from rat models.
Mesenchymal stem cells arouse myocardial NAD+ metabolism to alleviate microgravity-induced cardiac dysfunction.
Hapln1 promotes dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping.
DPP-4 inhibitor sitagliptin treatment results in altered myocardial metabolic proteome and oxidative phosphorylation in a swine model of chronic myocardial ischemia.
SUMOylation of TEAD1 Modulates the Mechanism of Pathological Cardiac Hypertrophy.
Detection of biomagnetic signals from induced pluripotent stem cell-derived cardiomyocytes using deep learning with simulation data.
Genetically Engineered Macrophages Co-Loaded with CD47 Inhibitors Synergistically Reconstruct Efferocytosis and Improve Cardiac Remodeling Post Myocardial Ischemia Reperfusion Injury.
Modulation of Titin and Contraction-Regulating Proteins in a Rat Model of Heart Failure with Preserved Ejection Fraction: Limb vs. Diaphragmatic Muscle.
N -N-Butyl Haloperidol Iodide Mitigates Myocardial Ischemia/Reperfusion Injury Through Activation of SIRT1-Nrf2 Signaling Loop.
Polystyrene microplastics enhance microcystin-LR-induced cardiovascular toxicity and oxidative stress in zebrafish embryos.
N-n-butyl haloperidol iodide mediates cardioprotection via regulating AMPK/FoxO1 signalling.
Targeting heat shock protein 47 alleviated doxorubicin-induced cardiotoxicity and remodeling in mice through suppression of the NLRP3 inflammasome.
A Self-Homing and Traceable Cardiac Patch Leveraging Ferumoxytol for Spatiotemporal Therapeutic Delivery.
Network pharmacology integrated with experimental validation to elucidate the mechanisms of action of the Guizhi-Gancao Decoction in the treatment of phenylephrine-induced cardiac hypertrophy.
The role of TREM-1 in septic myocardial pyroptosis and septic cardiomyopathy in vitro and in vivo.
Sweroside alleviates pressure overload-induced heart failure through targeting CaMKⅡδ to inhibit ROS-mediated NF-κB/NLRP3 in cardiomyocytes.
IFI-16 inhibition attenuates myocardial remodeling following myocardial infarction.
Functional enhancement of acute infracted heart by coinjection of autologous adipose-derived stem cells with matrigel.
Engineering a conduction-consistent cardiac patch with rGO/PLCL electrospun nanofibrous membranes and human iPSC-derived cardiomyocytes.
Ghrelin promotes cardiomyocyte differentiation of adipose tissue‑derived mesenchymal stem cells by DDX17‑mediated regulation of the SFRP4/Wnt/β‑catenin axis.
Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation.
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
BAK contributes critically to necrosis and infarct generation during reperfused myocardial infarction.
Cyclovirobuxine D alleviates aldosterone-induced myocardial hypertrophy by protecting mitochondrial function depending on the mutual regulation of Nrf2-SIRT3.
Engineering a conduction-consistent cardiac patch with graphene oxide modified butterfly wings and human pluripotent stem cell-derived cardiomyocytes.
Targeting the Divergent Roles of STK3 Inhibits Breast Cancer Cell Growth and Opposes Doxorubicin-Induced Cardiotoxicity In Vitro.
Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS.
Transient secretion of VEGF protein from transplanted hiPSC-CMs enhances engraftment and improves rat heart function post MI.
Fabrication Scaffold with High Dimensional Control for Spheroids with Undifferentiated iPS Cell Properties.
Electroacupuncture improves cardiac function after myocardial infarction by regulating the mobilization and migration of endogenous stem cells.
Hippo pathway-manipulating neutrophil-mimic hybrid nanoparticles for cardiac ischemic injury via modulation of local immunity and cardiac regeneration.
Sall1 and Sall4 cooperatively interact with Myocd and SRF to promote cardiomyocyte proliferation by regulating CDK and cyclin genes.
Silicate Ions Derived from Calcium Silicate Extract Decelerate Ang II-Induced Cardiac Remodeling.
Leaf-venation-directed cellular alignment for macroscale cardiac constructs with tissue-like functionalities.
Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether-à-go-go-Related Gene and Cav1.2.
Rev-erbs agonist SR9009 alleviates ischemia-reperfusion injury by heightening endogenous cardioprotection at onset of type-2 diabetes in rats: Down-regulating ferritinophagy/ferroptosis signaling.
Targeted delivery and ROS-responsive release of Resolvin D1 by platelet chimeric liposome ameliorates myocardial ischemia-reperfusion injury.
Overexpression of PYGO1 promotes early cardiac lineage development in human umbilical cord mesenchymal stromal/stem cells by activating the Wnt/β-catenin pathway.
Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy.
Loss of function of the nuclear envelope protein LEMD2 causes DNA damage-dependent cardiomyopathy.
Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart.
ERK/RSK-mediated phosphorylation of Y-box binding protein-1 aggravates diabetic cardiomyopathy by suppressing its interaction with deubiquitinase OTUB1.
Cell-type-specific labeling and profiling of glycans in living mice.
The interaction protein of SORBS2 in myocardial tissue to find out the pathogenic mechanism of LVNC disease.
Brahma safeguards canalization of cardiac mesoderm differentiation.
Identification of differential microRNAs and messenger RNAs resulting from ASXL transcriptional regulator 3 knockdown during during heart development.
Engineering extracellular vesicles with platelet membranes fusion enhanced targeted therapeutic angiogenesis in a mouse model of myocardial ischemia reperfusion.
Direct in vivo reprogramming with non-viral sequential targeting nanoparticles promotes cardiac regeneration.
Platelet-Like Fusogenic Liposome-Mediated Targeting Delivery of miR-21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia-Reperfusion Injury.
H3K9me2 regulates early transcription factors to promote mesenchymal stem‑cell differentiation into cardiomyocytes.
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Poly(I:C) preconditioning protects the heart against myocardial ischemia/reperfusion injury through TLR3/PI3K/Akt-dependent pathway.
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
miR-25 Promotes Cardiomyocyte Proliferation by Targeting FBXW7.
Intrinsic Color Sensing System Allows for Real-Time Observable Functional Changes on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Enrichment differentiation of human induced pluripotent stem cells into sinoatrial node-like cells by combined modulation of BMP, FGF, and RA signaling pathways.
Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling.
Regulation of Histone Acetylation on Expression Profiles of Potassium Channels During Cardiomyocyte Differentiation From Mouse Embryonic Stem Cells.
Insulin-like growth factor binding protein 4 enhances cardiomyocytes induction in murine-induced pluripotent stem cells.
Cardiac function is regulated by B56α-mediated targeting of protein phosphatase 2A (PP2A) to contractile relevant substrates.
A multifunctional protein, EWS, is essential for early brown fat lineage determination.
Knockdown of nucleosome assembly protein 1-like 1 promotes dimethyl sulfoxide-induced differentiation of P19CL6 cells into cardiomyocytes.
Zhang H, Tu S, Xu C, Wu R, Wu J, Huang X, Luo X, Luo X, Qu X
Stem cells international 2026;2026:5540587
Stem cells international 2026;2026:5540587
Galangin 3-methyl ether alleviates mouse hypertrophic cardiomyopathy via targeting HDAC2 and subsequently inactivating the PI3K-AKT signaling pathway.
Zhang K, Xu T, Heng XY, Lei JZ, Han DS, Huang SH, He MQ, Pu L, Wu YY, Sun N, Yang H, Ye C
Acta pharmacologica Sinica 2026 Mar;47(3):636-651
Acta pharmacologica Sinica 2026 Mar;47(3):636-651
Lithospermic Acid Improves Doxorubicin-Induced Cardiomyopathy Through Sirtuin-3-Mediated Deacetylation of p53.
Zhao Y, Xu T, Ye C, Zhang K, Heng X, Huang S, Chen Y, Guo Y, Shao S, Wen Z, Shao C, Lu X, Sun N, Yang H
Phytotherapy research : PTR 2026 Mar;40(3):965-985
Phytotherapy research : PTR 2026 Mar;40(3):965-985
Sustained release of dual p38 inhibitors via supramolecular hydrogels to enhance cardiac repair after MI/R injury.
Wang D, Xu A, Su H, Zhang Y, Jiang L, Wang Y, Liang G, Zhang Y
Biomaterials 2026 Mar;326:123670
Biomaterials 2026 Mar;326:123670
Development of low-cost electrical stimulation device to promote hiPSC-CM differentiation and functionality.
Kalkunte N, Sohn S, Callahan C, Delambre T, Momtahan N, Meng S, Brock A, Zoldan J
APL bioengineering 2026 Mar;10(1):016101
APL bioengineering 2026 Mar;10(1):016101
Ginkgolic acid ameliorates pressure overload-induced cardiac remodeling by inhibiting SAE1 and activating the NRF2/HMOX1 pathway.
Dang X, Ji Q, Huang Z, Yang N, Chi C, Zhao Y, Xu Y, Wang M, Liu Y, Jiang Z, Dai J, Li R, Gu C, Shi X, Hou X, Han W
Free radical biology & medicine 2026 Mar 1;245:185-200
Free radical biology & medicine 2026 Mar 1;245:185-200
Tissue-engineered cardiac patches enriched with IGF1 modified mRNA alleviate myocardial infarction by enhancing cell survival and angiogenesis.
Yan B, Ai X, Wang H, Tan Y, Gong Y, Yang L, Chen Y, Lu T, Liu M, Luo R, Li K, Tang X, Wang W, Fu W
Materials today. Bio 2026 Feb;36:102686
Materials today. Bio 2026 Feb;36:102686
Left bundle branch vs biventricular pacing: mechanistic insights from a canine model.
Huang H, Hu Y, Li H, Cheng S, Jiang Y, Weng S, He P, Yang J, Chen G, Liu X, Pei J, Chen L, Gu M, Ding L, Niu H, Jin H, Pan X, Vernooy K, Prinzen FW, Hua W
European heart journal 2026 Apr 1;47(13):1595-1605
European heart journal 2026 Apr 1;47(13):1595-1605
Imperatorin's Effect on Myocardial Infarction Based on Network Pharmacology and Molecular Docking.
Zhang R, Wang P, Jin Y, Xie Q, Xiao P
Cardiovascular therapeutics 2025;2025:7551459
Cardiovascular therapeutics 2025;2025:7551459
Screening and characterization of natural extracts as dual-functional regulators for cardiomyocyte regeneration and cardiac repair.
Liu J, Kuang C
Frontiers in cardiovascular medicine 2025;12:1701482
Frontiers in cardiovascular medicine 2025;12:1701482
Herb pair of Astragali Radix-Descurainiae Semen attenuate heart failure through the myosin VI-Tom1 complex mediated autophagy.
Wang M, Ni S, Wang T, Sun M, Wu Q, Wu X, Lu G, Su P, Gao Z, Chen Q
Frontiers in cardiovascular medicine 2025;12:1599746
Frontiers in cardiovascular medicine 2025;12:1599746
NMDA-Type Glutamate Receptor Activation Promotes Ischemic Arrhythmias by Targeting the AKT1-TBX3-Nav1.5 Axis.
He Y, Zhang H, Zhang Q, Sun Z, Sun X, Xia L, Zheng L, Wang L
Acta physiologica (Oxford, England) 2025 Sep;241(9):e70085
Acta physiologica (Oxford, England) 2025 Sep;241(9):e70085
Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis-Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis.
He R, Wu B, Han L, Li M, Guo W, Fu J, Mei B, Gross ER, Liu X, Lu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e04406
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e04406
Rab26-mediated lysosomal translocation of eEF1A alleviates myocardial hypertrophy and cardiac remodeling.
Tong Y, Li Y, Bi Y, Liu Y, Peng X, He B, Wang X
Life sciences 2025 Oct 1;378:123830
Life sciences 2025 Oct 1;378:123830
Mapping cardiac drug transport: In vitro assessment of cardiac P-glycoprotein function with [(18)F]MC225 by using µ-engineered heart tissues.
Liu W, Dannenberg M, Mossel P, Cai Z, Farinha Antunes I, Sijbesma J, Kwizera C, Cao L, van der Meer A, Passier R, Slart RHJA, Schwach V, Luurtsema G
European heart journal open 2025 Nov;5(6):oeaf150
European heart journal open 2025 Nov;5(6):oeaf150
HAND1 level controls the specification of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells.
Lynch AT, Phillips N, Douglas M, Dorgnach M, Lin IH, Adamson AD, Darieva Z, Whittle J, Hanley NA, Bobola N, Birket MJ
The EMBO journal 2025 May;44(9):2541-2565
The EMBO journal 2025 May;44(9):2541-2565
Myocardial delivery of miR30d with peptide-functionalized milk-derived extracellular vesicles for targeted treatment of hypertrophic heart failure.
Tong L, Wang Q, Zhang Y, Lai F, Xu J, Yin W, Zhang S, Wei G, Yin J, Yi H, Storm G, Wang Z, Huang R, Xu T, Wang JW
Biomaterials 2025 May;316:122976
Biomaterials 2025 May;316:122976
LncRNA NAV2-AS2 is critical for fibroblast-to-myofibroblast transition and cardiac fibrosis.
Rong R, Yuan T, Yan Z, Tan L, Wei X, Li G, Gao H, Zhang J, Zhao X, Zhang Z, Wang M, Liu G, Xia F, Kong X, Zhu L, Cai H, Chen J, Qin W
International journal of biological macromolecules 2025 May;306(Pt 1):141400
International journal of biological macromolecules 2025 May;306(Pt 1):141400
Inhibition of ULK1 attenuates ferroptosis-mediated cardiac hypertrophy via HMGA2/METTL14/SLC7A11 axis in mice.
Zhang M, Sha Y, Wang J, Qi H, Shi P, Liu Y, Jiang M, Ba L, Liu Y, Cao Y, Zhang Q, Sun H
European journal of pharmacology 2025 May 15;995:177416
European journal of pharmacology 2025 May 15;995:177416
Cathepsin K inhibition promotes efficient differentiation of human embryonic stem cells to mature cardiomyocytes by mediating glucolipid metabolism and cellular energy homeostasis.
Wang Y, Cui Y, Liu X, Liang S, Zhong L, Guo R
Stem cell research & therapy 2025 Mar 5;16(1):118
Stem cell research & therapy 2025 Mar 5;16(1):118
Inhibition of circALPK2 enhances proliferation and therapeutic potential of human pluripotent stem cell-derived cardiomyocytes in myocardial infarction.
Wu H, Jiang X, Fan H, Li J, Li Y, Lin Y, Zhao D, Han X, Yu M, Tang JM, Hu S, Lei W
Stem cell research & therapy 2025 Mar 1;16(1):107
Stem cell research & therapy 2025 Mar 1;16(1):107
Multi-stage cooperative ROS-responsive hydrogel platform for drug delivery in myocardial ischemia-reperfusion injury repair.
Luo Q, Cheng N, Yang Y, Shao N, Nie T, Chen J, Huang C, Zhang S, Huang Y, Ieong CM, Zhang X, Hu K, Xiao Z, Luo L
Materials today. Bio 2025 Jun;32:101854
Materials today. Bio 2025 Jun;32:101854
Skeletal Muscle Alterations in Different Phenotypes of Heart Failure with Preserved Ejection Fraction.
Vahle B, Klädtke R, Schauer A, Bowen TS, Wisløff U, Linke A, Adams V
International journal of molecular sciences 2025 Jun 27;26(13)
International journal of molecular sciences 2025 Jun 27;26(13)
Natural product library screening identifies Darutigenol for the treatment of myocardial infarction and ischemia/reperfusion injury.
Liu K, Zheng L, Huang QY, Li HJ, Li C, Zhao H, Ye ZB, Wang H, Qi XF, Wang M
Chinese medicine 2025 Jun 18;20(1):90
Chinese medicine 2025 Jun 18;20(1):90
Nuclear Receptor ERRγ Protects Against Cardiac Ischemic Injury by Suppressing GBP5-Mediated Myocardial Inflammation.
Qiu J, Che Q, Zhang Y, Chen M, Wei Z, Bai Y, Zhao T, Yan J, Wu Z, Fei Z, Wang Y, Wang Q, Li YG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70819
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70819
Single-nuclei multiomics analysis identifies abnormal cardiomyocytes in a murine model of cardiac development.
Leonard R, Zhao Y, Eliason S, Zimmerman K, Batz A, Hatcher CJ, Weiss RM, Sweat M, Li X, Amendt BA
Nature communications 2025 Jul 29;16(1):6947
Nature communications 2025 Jul 29;16(1):6947
Pannexin1 via P2rx7/amphiregulin contributes to cardiac fibrosis post myocardial infarction.
Deng N, You L, Guo H, Wei Y, Xu F, Chen D, Luo S, Huang S, Zuo S, Li W, Si X
Journal of molecular histology 2025 Jul 15;56(4):230
Journal of molecular histology 2025 Jul 15;56(4):230
Nicotinamide riboside promoted cardiac energetics and alleviated doxorubicin-induced cardiotoxicity via SIRT1/ERRα signal in human pluripotent stem cells-derived cardiomyocytes.
Wang R, Zhang H, Yi Q, Wang YP, Xu H, Tan B, Zhu J
Life sciences 2025 Jul 15;373:123685
Life sciences 2025 Jul 15;373:123685
N-Cadherin promotes cardiac regeneration by potentiating pro-mitotic β-Catenin signaling in cardiomyocytes.
Tsai YW, Tseng YS, Wu YS, Song WL, You MY, Hsu YC, Chen WP, Huang WH, Chng JC, Lim CL, Wei KH, Ben Lai SL, Lee WC, Yang KC
Nature communications 2025 Jan 21;16(1):896
Nature communications 2025 Jan 21;16(1):896
Generation and characterization of the LINC01405 knockout human embryonic stem cell line.
Xu Y, Wu H, Jiang J, Ye L, Hao K, Han K, Hu S, Lei W, Guo Z
Stem cell research 2025 Feb;82:103619
Stem cell research 2025 Feb;82:103619
MiR-133b-3p attenuates angiotensin II-induced cardiac hypertrophy through the inhibition of apoptosis by targeting CDIP1.
Gu J, Li Z, Li X, Yang Z, Xu X, Wang Y, Li X, Qin K, Li G, Xue L, Yang X
Acta biochimica et biophysica Sinica 2025 Feb 12;57(6):916-926
Acta biochimica et biophysica Sinica 2025 Feb 12;57(6):916-926
Nynrin enhances cardiac function by inhibiting mitochondrial permeability transition pore opening upon myocardial ischemia/reperfusion injury.
Wang Y, Li Y, Zhou Y, Zhang H, Zang J, Yang C, Gao Z, Hou Y, Song M
Journal of molecular and cellular cardiology 2025 Dec;209:93-103
Journal of molecular and cellular cardiology 2025 Dec;209:93-103
Targeting long-chain acylcarnitine accumulation to protect cardiac mitochondrial homeostasis after complete revascularization.
Lin R, Li Y, Yang S, Gao H, Li F, Wang X, Tan X, Wang Z, Chen W, Ren L, Wang X, Wang L, Qin J, Yin W, Du J, Wang Y
Cell reports. Medicine 2025 Dec 16;6(12):102507
Cell reports. Medicine 2025 Dec 16;6(12):102507
Y4 RNA fragment alleviates myocardial injury in heart transplantation via SNRNP200 to enhance IL-10 mRNA splicing.
Lu C, Meng Z, Tang S, Wei H, Hu Y, Chen D, Liu D, Wen H, Dong K, Na N, Huang F, Zeng Z
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Apr 2;33(4):1735-1748
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Apr 2;33(4):1735-1748
Whole genome transcriptomics reveal distinct atrial versus ventricular responses to neonatal hyperoxia.
Cohen ED, Yee M, Roethlin K, Prelipcean I, Small EM, Porter GA Jr, O'Reilly MA
American journal of physiology. Heart and circulatory physiology 2025 Apr 1;328(4):H832-H845
American journal of physiology. Heart and circulatory physiology 2025 Apr 1;328(4):H832-H845
Immune-checkpoint-inhibitor therapy directed against PD-L1 is tolerated in the heart without manifestation of cardiac inflammation in a preclinical reversible melanoma mouse model.
Schoenherr C, Pietzsch S, Barca C, Müller FE, Bahr FS, Kasten M, Zeug A, Erschow S, Falk CS, Ponimaskin E, Thackeray JT, Hilfiker-Kleiner D, Ricke-Hoch M
Frontiers in molecular medicine 2024;4:1487526
Frontiers in molecular medicine 2024;4:1487526
Gene Expression, Morphology, and Electrophysiology During the Dynamic Development of Human Induced Pluripotent Stem Cell-Derived Atrial- and Ventricular-Like Cardiomyocytes.
Zhou Y, Zhou R, Huang W, Wang J, Jiang C, Li A, Huang CLH, Zhang Y
Biologics : targets & therapy 2024;18:115-127
Biologics : targets & therapy 2024;18:115-127
Characterization of the m(6)A regulators' landscape highlights the clinical significance of acute myocardial infarction.
Chao P, Zhang X, Zhang L, Wang Y, Wusiman M, Aimaijiang G, Chen X, Yang Y
Frontiers in immunology 2024;15:1308978
Frontiers in immunology 2024;15:1308978
Leukocyte infiltration and cross-talk with cardiomyocytes exploit intracellular stress pathways in dilated cardiomyopathy of idiopathic origin.
Talukdar D, Haldar AK, Kumar S, Dastidar R, Basu A, Roy A, Sarkar S, Dey S, Sikder K
Molecular biology reports 2024 Oct 24;51(1):1090
Molecular biology reports 2024 Oct 24;51(1):1090
Colchicine prevents perioperative myocardial injury in cardiac surgery by inhibiting the formation of neutrophil extracellular traps: evidence from rat models.
Pan HD, Kong YR, Xu L, Liu MY, Lv ZK, Matniyaz Y, Zhang HT, Tang YX, Su WX, Jiang CY, Zhu YF, Wang DJ, Jiao XL, Pan T
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2024 Oct 1;66(4)
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2024 Oct 1;66(4)
Mesenchymal stem cells arouse myocardial NAD+ metabolism to alleviate microgravity-induced cardiac dysfunction.
Zhang C, Yuan Y, Zhang S, Yan N, Zhao Y, Lu L, Li K, Zhou S, Cai S, Liang F, Ji G, Qu Y, Lv K, Dai Y, Li B, Yan S, Li X, Qu L, Li Y
Biochemical and biophysical research communications 2024 Nov 12;733:150623
Biochemical and biophysical research communications 2024 Nov 12;733:150623
Hapln1 promotes dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping.
Hao DJ, Qin Y, Zhou SJ, Dong BH, Yang JS, Zou P, Wang LP, Zhao YT
Journal of pharmaceutical analysis 2024 Mar;14(3):335-347
Journal of pharmaceutical analysis 2024 Mar;14(3):335-347
DPP-4 inhibitor sitagliptin treatment results in altered myocardial metabolic proteome and oxidative phosphorylation in a swine model of chronic myocardial ischemia.
Harris DD, Sabe SA, Broadwin M, Bellam K, Xu CM, Li JW, Abid MR, Sellke FW
Physiological reports 2024 Mar;12(5):e15976
Physiological reports 2024 Mar;12(5):e15976
SUMOylation of TEAD1 Modulates the Mechanism of Pathological Cardiac Hypertrophy.
Shi X, Dang X, Huang Z, Lu Y, Tong H, Liang F, Zhuang F, Li Y, Cai Z, Huo H, Jiang Z, Pan C, Wang X, Gu C, He B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(12):e2305677
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(12):e2305677
Detection of biomagnetic signals from induced pluripotent stem cell-derived cardiomyocytes using deep learning with simulation data.
Yamaguchi T, Adachi Y, Tanida T, Taguchi K, Oka Y, Yoshida T, Kim WC, Takahashi K, Tanaka M
Scientific reports 2024 Mar 27;14(1):7296
Scientific reports 2024 Mar 27;14(1):7296
Genetically Engineered Macrophages Co-Loaded with CD47 Inhibitors Synergistically Reconstruct Efferocytosis and Improve Cardiac Remodeling Post Myocardial Ischemia Reperfusion Injury.
Tan H, Li W, Pang Z, Weng X, Gao J, Chen J, Wang Q, Li Q, Yang H, Dong Z, Wang Z, Zhu G, Tan Y, Fu Y, Han C, Cai S, Qian J, Huang Z, Song Y, Ge J
Advanced healthcare materials 2024 Jun;13(16):e2303267
Advanced healthcare materials 2024 Jun;13(16):e2303267
Modulation of Titin and Contraction-Regulating Proteins in a Rat Model of Heart Failure with Preserved Ejection Fraction: Limb vs. Diaphragmatic Muscle.
Vahle B, Heilmann L, Schauer A, Augstein A, Jarabo MP, Barthel P, Mangner N, Labeit S, Bowen TS, Linke A, Adams V
International journal of molecular sciences 2024 Jun 16;25(12)
International journal of molecular sciences 2024 Jun 16;25(12)
N -N-Butyl Haloperidol Iodide Mitigates Myocardial Ischemia/Reperfusion Injury Through Activation of SIRT1-Nrf2 Signaling Loop.
Lu B, Feng Z, Wang Y, Liao J, Wang B, Gao F, Zheng F, Shi G, Zhang Y
Journal of cardiovascular pharmacology 2024 Jun 1;83(6):602-611
Journal of cardiovascular pharmacology 2024 Jun 1;83(6):602-611
Polystyrene microplastics enhance microcystin-LR-induced cardiovascular toxicity and oxidative stress in zebrafish embryos.
Xiao Y, Hu L, Duan J, Che H, Wang W, Yuan Y, Xu J, Chen D, Zhao S
Environmental pollution (Barking, Essex : 1987) 2024 Jul 1;352:124022
Environmental pollution (Barking, Essex : 1987) 2024 Jul 1;352:124022
N-n-butyl haloperidol iodide mediates cardioprotection via regulating AMPK/FoxO1 signalling.
Lu B, Wu Z, He W, Feng Z, Liao J, Wang B, Zhang Y, Gao F, Shi G, Zheng F
Journal of cellular and molecular medicine 2024 Jan;28(2):e18049
Journal of cellular and molecular medicine 2024 Jan;28(2):e18049
Targeting heat shock protein 47 alleviated doxorubicin-induced cardiotoxicity and remodeling in mice through suppression of the NLRP3 inflammasome.
Shi W, Chen J, Zhao N, Xing Y, Liu S, Chen M, Fang W, Zhang T, Li L, Zhang H, Zhang M, Zeng X, Chen S, Wang S, Xie S, Deng W
Journal of molecular and cellular cardiology 2024 Jan;186:81-93
Journal of molecular and cellular cardiology 2024 Jan;186:81-93
A Self-Homing and Traceable Cardiac Patch Leveraging Ferumoxytol for Spatiotemporal Therapeutic Delivery.
Li M, Liu Y, Huang B, Zhou G, Pan M, Jin J, Wang F, Wang Y, Ren X, Xu B, Hu B, Gu N
ACS nano 2024 Jan 30;18(4):3073-3086
ACS nano 2024 Jan 30;18(4):3073-3086
Network pharmacology integrated with experimental validation to elucidate the mechanisms of action of the Guizhi-Gancao Decoction in the treatment of phenylephrine-induced cardiac hypertrophy.
Yang K, Shan X, Songru Y, Fu M, Zhao P, Guo W, Xu M, Chen H, Lu R, Zhang C
Pharmaceutical biology 2024 Dec;62(1):456-471
Pharmaceutical biology 2024 Dec;62(1):456-471
The role of TREM-1 in septic myocardial pyroptosis and septic cardiomyopathy in vitro and in vivo.
Chen Y, Mao L, Liu S, Huang S, Lin Q, Zeng M, Huang H, Sun X, Chen H, Huang J, Zhou G, Deng L
Journal of cellular physiology 2024 Dec;239(12):e31445
Journal of cellular physiology 2024 Dec;239(12):e31445
Sweroside alleviates pressure overload-induced heart failure through targeting CaMKⅡδ to inhibit ROS-mediated NF-κB/NLRP3 in cardiomyocytes.
Wang D, Yu X, Gao K, Li F, Li X, Pu H, Zhang P, Guo S, Wang W
Redox biology 2024 Aug;74:103223
Redox biology 2024 Aug;74:103223
IFI-16 inhibition attenuates myocardial remodeling following myocardial infarction.
Deng Y, Pang X, Chen L, Peng W, Huang X, Huang P, Zhao S, Li Z, Cai X, Huang Q, Zeng J, Feng Y, Chen B
iScience 2024 Aug 16;27(8):110568
iScience 2024 Aug 16;27(8):110568
Functional enhancement of acute infracted heart by coinjection of autologous adipose-derived stem cells with matrigel.
Wang BZ, Wang MM, Li Y, Shao MH, Zhang D, Yan SQ, Ma X, Ma YT
Turkish journal of biology = Turk biyoloji dergisi 2023;47(3):170-185
Turkish journal of biology = Turk biyoloji dergisi 2023;47(3):170-185
Engineering a conduction-consistent cardiac patch with rGO/PLCL electrospun nanofibrous membranes and human iPSC-derived cardiomyocytes.
Tan Y, Chen Y, Lu T, Witman N, Yan B, Gong Y, Ai X, Yang L, Liu M, Luo R, Wang H, Ministrini S, Dong W, Wang W, Fu W
Frontiers in bioengineering and biotechnology 2023;11:1094397
Frontiers in bioengineering and biotechnology 2023;11:1094397
Ghrelin promotes cardiomyocyte differentiation of adipose tissue‑derived mesenchymal stem cells by DDX17‑mediated regulation of the SFRP4/Wnt/β‑catenin axis.
Liu GB, Cheng YX, Li HM, Liu Y, Sun LX, Wu Q, Guo SF, Li TT, Dong CL, Sun G
Molecular medicine reports 2023 Sep;28(3)
Molecular medicine reports 2023 Sep;28(3)
Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation.
Wang J, Xie W, Li N, Li W, Zhang Z, Fan N, Ouyang Z, Zhao Y, Lai C, Li H, Chen M, Quan L, Li Y, Jiang Y, Jia W, Fu L, Mazid MA, Zhu Y, Maxwell PH, Pan G, Esteban MA, Dai Z, Lai L
Cell stem cell 2023 Sep 7;30(9):1235-1245.e6
Cell stem cell 2023 Sep 7;30(9):1235-1245.e6
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
Song K, Sun H, Tu B, Zhou Y, Lin LC, Liu ZY, Li R, Yang JJ, Zhang Y, Zhao JY, Tao H
iScience 2023 Oct 20;26(10):107931
iScience 2023 Oct 20;26(10):107931
BAK contributes critically to necrosis and infarct generation during reperfused myocardial infarction.
Qin D, Jia XF, Hanna A, Lee J, Pekson R, Elrod JW, Calvert JW, Frangogiannis NG, Kitsis RN
Journal of molecular and cellular cardiology 2023 Nov;184:1-12
Journal of molecular and cellular cardiology 2023 Nov;184:1-12
Cyclovirobuxine D alleviates aldosterone-induced myocardial hypertrophy by protecting mitochondrial function depending on the mutual regulation of Nrf2-SIRT3.
Wang X, Wu H, An J, Zhang G, Chen Y, Fu L, Tao L, Liang G, Shen X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115618
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115618
Engineering a conduction-consistent cardiac patch with graphene oxide modified butterfly wings and human pluripotent stem cell-derived cardiomyocytes.
Tan Y, Lu T, Chen Y, Witman N, Yan B, Yang L, Liu M, Gong Y, Ai X, Luo R, Wang H, Wang W, Fu W
Bioengineering & translational medicine 2023 May;8(3):e10522
Bioengineering & translational medicine 2023 May;8(3):e10522
Targeting the Divergent Roles of STK3 Inhibits Breast Cancer Cell Growth and Opposes Doxorubicin-Induced Cardiotoxicity In Vitro.
Nam J, Schirmer AU, Loh C, Drewry DH, Macias E
Cancers 2023 May 18;15(10)
Cancers 2023 May 18;15(10)
Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS.
Wu X, Liu L, Zheng Q, Ye H, Yang H, Hao H, Li P
Acta pharmaceutica Sinica. B 2023 Jan;13(1):113-127
Acta pharmaceutica Sinica. B 2023 Jan;13(1):113-127
Transient secretion of VEGF protein from transplanted hiPSC-CMs enhances engraftment and improves rat heart function post MI.
Ai X, Yan B, Witman N, Gong Y, Yang L, Tan Y, Chen Y, Liu M, Lu T, Luo R, Wang H, Chien KR, Wang W, Fu W
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jan 4;31(1):211-229
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jan 4;31(1):211-229
Fabrication Scaffold with High Dimensional Control for Spheroids with Undifferentiated iPS Cell Properties.
Togo H, Terada K, Ujitsugu A, Hirose Y, Takeuchi H, Kusunoki M
Cells 2023 Jan 11;12(2)
Cells 2023 Jan 11;12(2)
Electroacupuncture improves cardiac function after myocardial infarction by regulating the mobilization and migration of endogenous stem cells.
Xuan SS, Zhao Y, Zheng Y, Zhu J, Li H, Lu PP, Shao SJ, Guo HD, Mou FF
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2023 Dec;41(6):354-363
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2023 Dec;41(6):354-363
Hippo pathway-manipulating neutrophil-mimic hybrid nanoparticles for cardiac ischemic injury via modulation of local immunity and cardiac regeneration.
Wang Q, Song Y, Gao J, Li Q, Chen J, Xie Y, Wang Z, Tan H, Yang H, Zhang N, Qian J, Pang Z, Huang Z, Ge J
Acta pharmaceutica Sinica. B 2023 Dec;13(12):4999-5015
Acta pharmaceutica Sinica. B 2023 Dec;13(12):4999-5015
Sall1 and Sall4 cooperatively interact with Myocd and SRF to promote cardiomyocyte proliferation by regulating CDK and cyclin genes.
Katano W, Mori S, Sasaki S, Tajika Y, Tomita K, Takeuchi JK, Koshiba-Takeuchi K
Development (Cambridge, England) 2023 Dec 15;150(24)
Development (Cambridge, England) 2023 Dec 15;150(24)
Silicate Ions Derived from Calcium Silicate Extract Decelerate Ang II-Induced Cardiac Remodeling.
Li X, Zhang Y, Jin Q, Song Q, Fan C, Jiao Y, Yang C, Chang J, Dong Z, Que Y
Tissue engineering and regenerative medicine 2023 Aug;20(5):671-681
Tissue engineering and regenerative medicine 2023 Aug;20(5):671-681
Leaf-venation-directed cellular alignment for macroscale cardiac constructs with tissue-like functionalities.
Mao M, Qu X, Zhang Y, Gu B, Li C, Liu R, Li X, Zhu H, He J, Li D
Nature communications 2023 Apr 12;14(1):2077
Nature communications 2023 Apr 12;14(1):2077
Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether-à-go-go-Related Gene and Cav1.2.
Zheng Z, Cai D, Fu Y, Wang Y, Song Y, Lian J
Frontiers in pharmacology 2022;13:889713
Frontiers in pharmacology 2022;13:889713
Rev-erbs agonist SR9009 alleviates ischemia-reperfusion injury by heightening endogenous cardioprotection at onset of type-2 diabetes in rats: Down-regulating ferritinophagy/ferroptosis signaling.
Huang Q, Tian L, Zhao X, Lei S, Zhao B, Qiu Z, Xia ZY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113595
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113595
Targeted delivery and ROS-responsive release of Resolvin D1 by platelet chimeric liposome ameliorates myocardial ischemia-reperfusion injury.
Weng X, Tan H, Huang Z, Chen J, Zhang N, Wang Q, Li Q, Gao J, Sun D, Yakufu W, Wang Z, Li W, Zhu G, Pang Z, Song Y, Qian J, Ge J
Journal of nanobiotechnology 2022 Oct 20;20(1):454
Journal of nanobiotechnology 2022 Oct 20;20(1):454
Overexpression of PYGO1 promotes early cardiac lineage development in human umbilical cord mesenchymal stromal/stem cells by activating the Wnt/β-catenin pathway.
Shen J, Wu X, Zhu P, Zhuang J, Qin B, Sun F, Yuan W, Fan X, Jiang Z, Li F, Li Y, Wang Y, Zhao M
Human cell 2022 Nov;35(6):1722-1735
Human cell 2022 Nov;35(6):1722-1735
Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy.
Nishiyama T, Zhang Y, Cui M, Li H, Sanchez-Ortiz E, McAnally JR, Tan W, Kim J, Chen K, Xu L, Bassel-Duby R, Olson EN
Science translational medicine 2022 Nov 23;14(672):eade1633
Science translational medicine 2022 Nov 23;14(672):eade1633
Loss of function of the nuclear envelope protein LEMD2 causes DNA damage-dependent cardiomyopathy.
Caravia XM, Ramirez-Martinez A, Gan P, Wang F, McAnally JR, Xu L, Bassel-Duby R, Liu N, Olson EN
The Journal of clinical investigation 2022 Nov 15;132(22)
The Journal of clinical investigation 2022 Nov 15;132(22)
Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart.
Hulikova A, Park KC, Loonat AA, Gunadasa-Rohling M, Curtis MK, Chung YJ, Wilson A, Carr CA, Trafford AW, Fournier M, Moshnikova A, Andreev OA, Reshetnyak YK, Riley PR, Smart N, Milne TA, Crump NT, Swietach P
Basic research in cardiology 2022 Mar 31;117(1):17
Basic research in cardiology 2022 Mar 31;117(1):17
ERK/RSK-mediated phosphorylation of Y-box binding protein-1 aggravates diabetic cardiomyopathy by suppressing its interaction with deubiquitinase OTUB1.
Zhong X, Wang T, Zhang W, Wang M, Xie Y, Dai L, He X, Madhusudhan T, Zeng H, Wang H
The Journal of biological chemistry 2022 Jun;298(6):101989
The Journal of biological chemistry 2022 Jun;298(6):101989
Cell-type-specific labeling and profiling of glycans in living mice.
Fan X, Song Q, Sun DE, Hao Y, Wang J, Wang C, Chen X
Nature chemical biology 2022 Jun;18(6):625-633
Nature chemical biology 2022 Jun;18(6):625-633
The interaction protein of SORBS2 in myocardial tissue to find out the pathogenic mechanism of LVNC disease.
Li C, Zheng Y, Liu Y, Jin GH, Pan H, Yin F, Wu J
Aging 2022 Jan 20;14(2):800-810
Aging 2022 Jan 20;14(2):800-810
Brahma safeguards canalization of cardiac mesoderm differentiation.
Hota SK, Rao KS, Blair AP, Khalilimeybodi A, Hu KM, Thomas R, So K, Kameswaran V, Xu J, Polacco BJ, Desai RV, Chatterjee N, Hsu A, Muncie JM, Blotnick AM, Winchester SAB, Weinberger LS, Hüttenhain R, Kathiriya IS, Krogan NJ, Saucerman JJ, Bruneau BG
Nature 2022 Feb;602(7895):129-134
Nature 2022 Feb;602(7895):129-134
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Liu ZQ, Cheng M, Fu F, Li R, Han J, Yang X, Deng Q, Li LS, Lei TY, Li DZ, Liao C
Bioengineered 2022 Apr;13(4):9948-9961
Bioengineered 2022 Apr;13(4):9948-9961
Engineering extracellular vesicles with platelet membranes fusion enhanced targeted therapeutic angiogenesis in a mouse model of myocardial ischemia reperfusion.
Li Q, Song Y, Wang Q, Chen J, Gao J, Tan H, Li S, Wu Y, Yang H, Huang H, Yu Y, Li Y, Zhang N, Huang Z, Pang Z, Qian J, Ge J
Theranostics 2021;11(8):3916-3931
Theranostics 2021;11(8):3916-3931
Direct in vivo reprogramming with non-viral sequential targeting nanoparticles promotes cardiac regeneration.
Wang Q, Song Y, Chen J, Li Q, Gao J, Tan H, Zhu Y, Wang Z, Li M, Yang H, Zhang N, Li X, Qian J, Pang Z, Huang Z, Ge J
Biomaterials 2021 Sep;276:121028
Biomaterials 2021 Sep;276:121028
Platelet-Like Fusogenic Liposome-Mediated Targeting Delivery of miR-21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia-Reperfusion Injury.
Tan H, Song Y, Chen J, Zhang N, Wang Q, Li Q, Gao J, Yang H, Dong Z, Weng X, Wang Z, Sun D, Yakufu W, Pang Z, Huang Z, Ge J
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Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Aug;8(15):e2100787
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Sun X, Gu X, Li H, Xu P, Li M, Zhu Y, Zuo Q, Li B
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
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Sun X, Li H, Zhu Y, Xu P, Zuo Q, Li B, Gu X
Stem cells international 2020;2020:5162350
Stem cells international 2020;2020:5162350
Poly(I:C) preconditioning protects the heart against myocardial ischemia/reperfusion injury through TLR3/PI3K/Akt-dependent pathway.
Chen E, Chen C, Niu Z, Gan L, Wang Q, Li M, Cai X, Gao R, Katakam S, Chen H, Zhang S, Zhou R, Cheng X, Qiu Y, Yu H, Zhu T, Liu J
Signal transduction and targeted therapy 2020 Nov 6;5(1):216
Signal transduction and targeted therapy 2020 Nov 6;5(1):216
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Li C, Liu F, Liu S, Pan H, Du H, Huang J, Xie Y, Li Y, Zhao R, Wei Y
EBioMedicine 2020 Mar;53:102695
EBioMedicine 2020 Mar;53:102695
miR-25 Promotes Cardiomyocyte Proliferation by Targeting FBXW7.
Wang B, Xu M, Li M, Wu F, Hu S, Chen X, Zhao L, Huang Z, Lan F, Liu D, Wang Y
Molecular therapy. Nucleic acids 2020 Mar 6;19:1299-1308
Molecular therapy. Nucleic acids 2020 Mar 6;19:1299-1308
Intrinsic Color Sensing System Allows for Real-Time Observable Functional Changes on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Gong Y, Chen Z, Yang L, Ai X, Yan B, Wang H, Qiu L, Tan Y, Witman N, Wang W, Zhao Y, Fu W
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Stem cell research & therapy 2020 Jul 16;11(1):284
Stem cell research & therapy 2020 Jul 16;11(1):284
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Clinical science (London, England : 1979) 2019 Jan 31;133(2):225-238
Clinical science (London, England : 1979) 2019 Jan 31;133(2):225-238
Regulation of Histone Acetylation on Expression Profiles of Potassium Channels During Cardiomyocyte Differentiation From Mouse Embryonic Stem Cells.
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Journal of cellular biochemistry 2017 Dec;118(12):4460-4467
Insulin-like growth factor binding protein 4 enhances cardiomyocytes induction in murine-induced pluripotent stem cells.
Xue Y, Yan Y, Gong H, Fang B, Zhou Y, Ding Z, Yin P, Zhang G, Ye Y, Yang C, Ge J, Zou Y
Journal of cellular biochemistry 2014 Sep;115(9):1495-504
Journal of cellular biochemistry 2014 Sep;115(9):1495-504
Cardiac function is regulated by B56α-mediated targeting of protein phosphatase 2A (PP2A) to contractile relevant substrates.
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The Journal of biological chemistry 2014 Dec 5;289(49):33862-73
A multifunctional protein, EWS, is essential for early brown fat lineage determination.
Park JH, Kang HJ, Kang SI, Lee JE, Hur J, Ge K, Mueller E, Li H, Lee BC, Lee SB
Developmental cell 2013 Aug 26;26(4):393-404
Developmental cell 2013 Aug 26;26(4):393-404
Knockdown of nucleosome assembly protein 1-like 1 promotes dimethyl sulfoxide-induced differentiation of P19CL6 cells into cardiomyocytes.
Li L, Gong H, Yu H, Liu X, Liu Q, Yan G, Zhang Y, Lu H, Zou Y, Yang P
Journal of cellular biochemistry 2012 Dec;113(12):3788-96
Journal of cellular biochemistry 2012 Dec;113(12):3788-96
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 15513-1-AP(TNNT2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of HepG2 cells, using TNNT2 antibody 15513-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 15513-1-AP(TNNT2 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue