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- References [21]
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- Product number
- 18810-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18810-1-AP, RRID:AB_10598463
- Product name
- INO80 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated INO80 antibody (Cat. #18810-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exploring Transcriptional Regulation of Beta Cell SASP by Brd4-Associated Proteins and Cell Cycle Control Protein p21.
INO80 function is required for mouse mammary gland development, but mutation alone may be insufficient for breast cancer.
Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair.
Cohesin-independent STAG proteins interact with RNA and R-loops and promote complex loading.
Photobiomodulation Drives MiR-136-5p Expression to Promote Injury Repair after Myocardial Infarction.
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1.
The transcriptional coactivator RUVBL2 regulates Pol II clustering with diverse transcription factors.
HIRA complex presets transcriptional potential through coordinating depositions of the histone variants H3.3 and H2A.Z on the poised genes in mESCs.
Mammalian SWI/SNF continuously restores local accessibility to chromatin.
Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin.
INO80 participates in the pathogenesis of recurrent miscarriage by epigenetically regulating trophoblast migration and invasion.
Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability.
Linc-MYH configures INO80 to regulate muscle stem cell numbers and skeletal muscle hypertrophy.
BZLF1 interacts with chromatin remodelers promoting escape from latent infections with EBV.
INO80 is required for oncogenic transcription and tumor growth in non-small cell lung cancer.
Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals.
Ino80 promotes cervical cancer tumorigenesis by activating Nanog expression.
Ino80 is essential for proximal-distal axis asymmetry in part by regulating Bmp4 expression.
INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma.
The Mouse INO80 Chromatin-Remodeling Complex Is an Essential Meiotic Factor for Spermatogenesis.
INO80 facilitates pluripotency gene activation in embryonic stem cell self-renewal, reprogramming, and blastocyst development.
Manji J, Pipella J, Brawerman G, Thompson PJ
Epigenomes 2024 Mar 6;8(1)
Epigenomes 2024 Mar 6;8(1)
INO80 function is required for mouse mammary gland development, but mutation alone may be insufficient for breast cancer.
Thang NX, Han DW, Park C, Lee H, La H, Yoo S, Lee H, Uhm SJ, Song H, Do JT, Park KS, Choi Y, Hong K
Frontiers in cell and developmental biology 2023;11:1253274
Frontiers in cell and developmental biology 2023;11:1253274
Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair.
Nguyen DD, Kim E, Le NT, Ding X, Jaiswal RK, Kostlan RJ, Nguyen TNT, Shiva O, Le MT, Chai W
Science advances 2023 May 10;9(19):eadd8023
Science advances 2023 May 10;9(19):eadd8023
Cohesin-independent STAG proteins interact with RNA and R-loops and promote complex loading.
Porter H, Li Y, Neguembor MV, Beltran M, Varsally W, Martin L, Cornejo MT, Pezić D, Bhamra A, Surinova S, Jenner RG, Cosma MP, Hadjur S
eLife 2023 Apr 3;12
eLife 2023 Apr 3;12
Photobiomodulation Drives MiR-136-5p Expression to Promote Injury Repair after Myocardial Infarction.
Gao X, Li H, Zhang W, Wang X, Sun H, Cao Y, Zhao Y, Ji H, Yang F, Ma W, Liu Y, Yang B, Cai B
International journal of biological sciences 2022;18(7):2980-2993
International journal of biological sciences 2022;18(7):2980-2993
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1.
Liu X, Chen J, Zhang S, Liu X, Long X, Lan J, Zhou M, Zheng L, Zhou J
EMBO reports 2022 Sep 5;23(9):e54128
EMBO reports 2022 Sep 5;23(9):e54128
The transcriptional coactivator RUVBL2 regulates Pol II clustering with diverse transcription factors.
Wang H, Li B, Zuo L, Wang B, Yan Y, Tian K, Zhou R, Wang C, Chen X, Jiang Y, Zheng H, Qin F, Zhang B, Yu Y, Liu CP, Xu Y, Gao J, Qi Z, Deng W, Ji X
Nature communications 2022 Sep 28;13(1):5703
Nature communications 2022 Sep 28;13(1):5703
HIRA complex presets transcriptional potential through coordinating depositions of the histone variants H3.3 and H2A.Z on the poised genes in mESCs.
Yang Y, Zhang L, Xiong C, Chen J, Wang L, Wen Z, Yu J, Chen P, Xu Y, Jin J, Cai Y, Li G
Nucleic acids research 2022 Jan 11;50(1):191-206
Nucleic acids research 2022 Jan 11;50(1):191-206
Mammalian SWI/SNF continuously restores local accessibility to chromatin.
Iurlaro M, Stadler MB, Masoni F, Jagani Z, Galli GG, Schübeler D
Nature genetics 2021 Mar;53(3):279-287
Nature genetics 2021 Mar;53(3):279-287
Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin.
Skalska L, Begley V, Beltran M, Lukauskas S, Khandelwal G, Faull P, Bhamra A, Tavares M, Wellman R, Tvardovskiy A, Foster BM, Ruiz de Los Mozos I, Herrero J, Surinova S, Snijders AP, Bartke T, Jenner RG
Molecular cell 2021 Jul 15;81(14):2944-2959.e10
Molecular cell 2021 Jul 15;81(14):2944-2959.e10
INO80 participates in the pathogenesis of recurrent miscarriage by epigenetically regulating trophoblast migration and invasion.
Xian S, Zhang Y, Wang L, Yao F, Ding J, Wang Y, Yang X, Dai F, Yin T, Cheng Y
Journal of cellular and molecular medicine 2021 Apr;25(8):3885-3897
Journal of cellular and molecular medicine 2021 Apr;25(8):3885-3897
Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability.
Prendergast L, McClurg UL, Hristova R, Berlinguer-Palmini R, Greener S, Veitch K, Hernandez I, Pasero P, Rico D, Higgins JMG, Gospodinov A, Papamichos-Chronakis M
Nature communications 2020 Sep 10;11(1):4534
Nature communications 2020 Sep 10;11(1):4534
Linc-MYH configures INO80 to regulate muscle stem cell numbers and skeletal muscle hypertrophy.
Schutt C, Hallmann A, Hachim S, Klockner I, Valussi M, Atzberger A, Graumann J, Braun T, Boettger T
The EMBO journal 2020 Nov 16;39(22):e105098
The EMBO journal 2020 Nov 16;39(22):e105098
BZLF1 interacts with chromatin remodelers promoting escape from latent infections with EBV.
Schaeffner M, Mrozek-Gorska P, Buschle A, Woellmer A, Tagawa T, Cernilogar FM, Schotta G, Krietenstein N, Lieleg C, Korber P, Hammerschmidt W
Life science alliance 2019 Apr;2(2)
Life science alliance 2019 Apr;2(2)
INO80 is required for oncogenic transcription and tumor growth in non-small cell lung cancer.
Zhang S, Zhou B, Wang L, Li P, Bennett BD, Snyder R, Garantziotis S, Fargo DC, Cox AD, Chen L, Hu G
Oncogene 2017 Mar;36(10):1430-1439
Oncogene 2017 Mar;36(10):1430-1439
Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals.
Xue Y, Pradhan SK, Sun F, Chronis C, Tran N, Su T, Van C, Vashisht A, Wohlschlegel J, Peterson CL, Timmers HTM, Kurdistani SK, Carey MF
Molecular cell 2017 Aug 17;67(4):594-607.e4
Molecular cell 2017 Aug 17;67(4):594-607.e4
Ino80 promotes cervical cancer tumorigenesis by activating Nanog expression.
Hu J, Liu J, Chen A, Lyu J, Ai G, Zeng Q, Sun Y, Chen C, Wang J, Qiu J, Wu Y, Cheng J, Shi X, Song L
Oncotarget 2016 Nov 1;7(44):72250-72262
Oncotarget 2016 Nov 1;7(44):72250-72262
Ino80 is essential for proximal-distal axis asymmetry in part by regulating Bmp4 expression.
Qiu Z, Elsayed Z, Peterkin V, Alkatib S, Bennett D, Landry JW
BMC biology 2016 Mar 14;14:18
BMC biology 2016 Mar 14;14:18
INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma.
Zhou B, Wang L, Zhang S, Bennett BD, He F, Zhang Y, Xiong C, Han L, Diao L, Li P, Fargo DC, Cox AD, Hu G
Genes & development 2016 Jun 15;30(12):1440-53
Genes & development 2016 Jun 15;30(12):1440-53
The Mouse INO80 Chromatin-Remodeling Complex Is an Essential Meiotic Factor for Spermatogenesis.
Serber DW, Runge JS, Menon DU, Magnuson T
Biology of reproduction 2016 Jan;94(1):8
Biology of reproduction 2016 Jan;94(1):8
INO80 facilitates pluripotency gene activation in embryonic stem cell self-renewal, reprogramming, and blastocyst development.
Wang L, Du Y, Ward JM, Shimbo T, Lackford B, Zheng X, Miao YL, Zhou B, Han L, Fargo DC, Jothi R, Williams CJ, Wade PA, Hu G
Cell stem cell 2014 May 1;14(5):575-91
Cell stem cell 2014 May 1;14(5):575-91
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The INO80 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human INO80. This antibody recognizes human, mouse, rat antigen. The INO80 antibody has been validated for the following applications: ELISA, WB analysis.
