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- References [5]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 18088-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18088-1-AP, RRID:AB_10859777
- Product name
- PLA2G4E antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PLA2G4E antibody (Cat. #18088-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Elamipretide alleviates pyroptosis in traumatically injured spinal cord by inhibiting cPLA2-induced lysosomal membrane permeabilization.
Group IVE cytosolic phospholipase A(2) limits psoriatic inflammation by mobilizing the anti-inflammatory lipid N-acylethanolamine.
Inhibition of PLA2G4E/cPLA2 promotes survival of random skin flaps by alleviating Lysosomal membrane permeabilization-Induced necroptosis.
Deletion of the Capn1 Gene Results in Alterations in Signaling Pathways Related to Alzheimer's Disease, Protein Quality Control and Synaptic Plasticity in Mouse Brain.
PLA2G4E, a candidate gene for resilience in Alzheimer´s disease and a new target for dementia treatment.
Zhang H, Chen Y, Li F, Wu C, Cai W, Ye H, Su H, He M, Yang L, Wang X, Zhou K, Ni W
Journal of neuroinflammation 2023 Jan 7;20(1):6
Journal of neuroinflammation 2023 Jan 7;20(1):6
Group IVE cytosolic phospholipase A(2) limits psoriatic inflammation by mobilizing the anti-inflammatory lipid N-acylethanolamine.
Liang L, Takamiya R, Miki Y, Heike K, Taketomi Y, Sugimoto N, Yamaguchi M, Shitara H, Nishito Y, Kobayashi T, Hirabayashi T, Murakami M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22301
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22301
Inhibition of PLA2G4E/cPLA2 promotes survival of random skin flaps by alleviating Lysosomal membrane permeabilization-Induced necroptosis.
Lou J, Wang X, Zhang H, Yu G, Ding J, Zhu X, Li Y, Wu Y, Xu H, Xu H, Gao W, Xiao J, Zhou K
Autophagy 2022 Aug;18(8):1841-1863
Autophagy 2022 Aug;18(8):1841-1863
Deletion of the Capn1 Gene Results in Alterations in Signaling Pathways Related to Alzheimer's Disease, Protein Quality Control and Synaptic Plasticity in Mouse Brain.
Su W, Zhou Q, Wang Y, Chishti A, Li QQ, Dayal S, Shiehzadegan S, Cheng A, Moore C, Bi X, Baudry M
Frontiers in genetics 2020;11:334
Frontiers in genetics 2020;11:334
PLA2G4E, a candidate gene for resilience in Alzheimer´s disease and a new target for dementia treatment.
Pérez-González M, Mendioroz M, Badesso S, Sucunza D, Roldan M, Espelosín M, Ursua S, Luján R, Cuadrado-Tejedor M, Garcia-Osta A
Progress in neurobiology 2020 Aug;191:101818
Progress in neurobiology 2020 Aug;191:101818
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 18088-1-AP(PLA2G4E antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skeletal muscle using 18088-1-AP(PLA2G4E antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PLA2G4E antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PLA2G4E. This antibody recognizes human, mouse, rat antigen. The PLA2G4E antibody has been validated for the following applications: ELISA, WB, IHC analysis.
