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- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 22142-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22142-1-AP, RRID:AB_11183045
- Product name
- RCC1 antibody
- Antibody type
- Polyclonal
- Description
- RCC1 antibody (Cat. #22142-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references KRAS(G12D) mutation promotes pancreatic tumorigenesis by suppressing sirtuin three via the guanine nucleotide exchange factor RCC1.
Regulator of chromosome condensation 1 promotes hepatocellular carcinoma proliferation via cell-division-cycle-associated-8 dependent phosphoinositide 3-kinase/protein kinase B signaling.
SNORA73B promotes endometrial cancer progression through targeting MIB1 and regulating host gene RCC1 alternative splicing.
Structure-Activity Relationship Studies of Venglustat on NTMT1 Inhibition.
Venglustat Inhibits Protein N-Terminal Methyltransferase 1 in a Substrate-Competitive Manner.
Age-dependent changes in nuclear-cytoplasmic signaling in skeletal muscle.
Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies.
Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development.
Regulator of chromatin condensation 1 abrogates the G1 cell cycle checkpoint via Cdk1 in human papillomavirus E7-expressing epithelium and cervical cancer cells.
Combination antitumor immunotherapy with VEGF and PIGF siRNA via systemic delivery of multi-functionalized nanoparticles to tumor-associated macrophages and breast cancer cells.
Mai T, Wang M, Qiu Y, Lu W, Wu H, Chen S, Chiao PJ, Huang P
The Journal of biological chemistry 2026 Feb;302(2):111057
The Journal of biological chemistry 2026 Feb;302(2):111057
Regulator of chromosome condensation 1 promotes hepatocellular carcinoma proliferation via cell-division-cycle-associated-8 dependent phosphoinositide 3-kinase/protein kinase B signaling.
Wang YT, Yong YL, Liu ZK, Shen YX, Yang XM, Chen ZN
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106080
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106080
SNORA73B promotes endometrial cancer progression through targeting MIB1 and regulating host gene RCC1 alternative splicing.
Chen X, Li QH, Xie BM, Ji YM, Han Y, Zhao Y
Journal of cellular and molecular medicine 2023 Oct;27(19):2890-2905
Journal of cellular and molecular medicine 2023 Oct;27(19):2890-2905
Structure-Activity Relationship Studies of Venglustat on NTMT1 Inhibition.
Deng Y, Dong G, Meng Y, Noinaj N, Huang R
Journal of medicinal chemistry 2023 Jan 26;66(2):1601-1615
Journal of medicinal chemistry 2023 Jan 26;66(2):1601-1615
Venglustat Inhibits Protein N-Terminal Methyltransferase 1 in a Substrate-Competitive Manner.
Dong G, Deng Y, Yasgar A, Yadav R, Talley D, Zakharov AV, Jain S, Rai G, Noinaj N, Simeonov A, Huang R
Journal of medicinal chemistry 2022 Sep 22;65(18):12334-12345
Journal of medicinal chemistry 2022 Sep 22;65(18):12334-12345
Age-dependent changes in nuclear-cytoplasmic signaling in skeletal muscle.
Iyer SR, Hsia RC, Folker ES, Lovering RM
Experimental gerontology 2021 Jul 15;150:111338
Experimental gerontology 2021 Jul 15;150:111338
Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies.
Mackie BD, Chen D, Dong G, Dong C, Parker H, Schaner Tooley CE, Noinaj N, Min J, Huang R
Journal of medicinal chemistry 2020 Sep 10;63(17):9512-9522
Journal of medicinal chemistry 2020 Sep 10;63(17):9512-9522
Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development.
Vargas-Hurtado D, Brault JB, Piolot T, Leconte L, Da Silva N, Pennetier C, Baffet A, Marthiens V, Basto R
Current biology : CB 2019 Sep 23;29(18):2993-3005.e9
Current biology : CB 2019 Sep 23;29(18):2993-3005.e9
Regulator of chromatin condensation 1 abrogates the G1 cell cycle checkpoint via Cdk1 in human papillomavirus E7-expressing epithelium and cervical cancer cells.
Qiao L, Zheng J, Tian Y, Zhang Q, Wang X, Chen JJ, Zhang W
Cell death & disease 2018 May 22;9(6):583
Cell death & disease 2018 May 22;9(6):583
Combination antitumor immunotherapy with VEGF and PIGF siRNA via systemic delivery of multi-functionalized nanoparticles to tumor-associated macrophages and breast cancer cells.
Song Y, Tang C, Yin C
Biomaterials 2018 Dec;185:117-132
Biomaterials 2018 Dec;185:117-132
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 22142-1-AP(RCC1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-RCC1 (IP:22142-1-AP, 3ug; Detection:22142-1-AP 1:1000) with HEK-293 cells lysate 1000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 22142-1-AP(RCC1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RCC1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human RCC1. This antibody recognizes human,mouse,rat, monkey antigen. The RCC1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
