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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 12347-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12347-1-AP, RRID:AB_2265988
- Product name
- MAGOH antibody
- Antibody type
- Polyclonal
- Description
- MAGOH antibody (Cat. #12347-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Splicing factor SF3B4 acts as a switch in cancer cell senescence by regulating p21 mRNA stability.
The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton.
MAGOH is correlated with poor prognosis and is essential for cell proliferation in lower-grade glioma.
An RNAi screen of RNA helicases identifies eIF4A3 as a regulator of embryonic stem cell identity.
Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome.
NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis.
Dosage-dependent requirements of Magoh for cortical interneuron generation and survival.
Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly.
Generation of a Magoh conditional allele in mice.
The exon junction complex component Magoh controls brain size by regulating neural stem cell division.
Mago, a vertebrate homolog of Drosophila Mago nashi protein, is a component of the chromatoid body in the cytoplasm of the postmeiotic spermatid.
Kang D, Sung JY, Hwang HJ, Baek Y, Kim MJ, Lim GE, Kim YN, Cha JH, Lee JS
Cancer letters 2025 Apr 10;615:217530
Cancer letters 2025 Apr 10;615:217530
The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton.
Alsina FC, Lupan BM, Lin LJ, Musso CM, Mosti F, Newman CR, Wood LM, Suzuki A, Agostino M, Moore JK, Silver DL
Cell reports 2024 Sep 24;43(9):114666
Cell reports 2024 Sep 24;43(9):114666
MAGOH is correlated with poor prognosis and is essential for cell proliferation in lower-grade glioma.
Xiao F, Long Z, Guo Y, Zhu H, Zhang Z, Xiao Y, Hu G, Yang Q, Huang K, Guo H
Aging 2023 Jun 30;15(12):5713-5733
Aging 2023 Jun 30;15(12):5713-5733
An RNAi screen of RNA helicases identifies eIF4A3 as a regulator of embryonic stem cell identity.
Li D, Yang J, Malik V, Huang Y, Huang X, Zhou H, Wang J
Nucleic acids research 2022 Nov 28;50(21):12462-12479
Nucleic acids research 2022 Nov 28;50(21):12462-12479
Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome.
Kuzuoglu-Ozturk D, Hu Z, Rama M, Devericks E, Weiss J, Chiang GG, Worland ST, Brenner SE, Goodarzi H, Gilbert LA, Ruggero D
Cell reports 2021 Jun 29;35(13):109321
Cell reports 2021 Jun 29;35(13):109321
NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis.
Park MK, Zhang L, Min KW, Cho JH, Yeh CC, Moon H, Hormaechea-Agulla D, Mun H, Ko S, Lee JW, Jathar S, Smith AS, Yao Y, Giang NT, Vu HH, Yan VC, Bridges MC, Kourtidis A, Muller F, Chang JH, Song SJ, Nakagawa S, Hirose T, Yoon JH, Song MS
Cell metabolism 2021 Dec 7;33(12):2380-2397.e9
Cell metabolism 2021 Dec 7;33(12):2380-2397.e9
Dosage-dependent requirements of Magoh for cortical interneuron generation and survival.
Sheehan CJ, McMahon JJ, Serdar LD, Silver DL
Development (Cambridge, England) 2020 Jan 13;147(1)
Development (Cambridge, England) 2020 Jan 13;147(1)
Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly.
Mao H, McMahon JJ, Tsai YH, Wang Z, Silver DL
PLoS genetics 2016 Sep;12(9):e1006282
PLoS genetics 2016 Sep;12(9):e1006282
Generation of a Magoh conditional allele in mice.
McMahon JJ, Shi L, Silver DL
Genesis (New York, N.Y. : 2000) 2014 Aug;52(8):752-8
Genesis (New York, N.Y. : 2000) 2014 Aug;52(8):752-8
The exon junction complex component Magoh controls brain size by regulating neural stem cell division.
Silver DL, Watkins-Chow DE, Schreck KC, Pierfelice TJ, Larson DM, Burnetti AJ, Liaw HJ, Myung K, Walsh CA, Gaiano N, Pavan WJ
Nature neuroscience 2010 May;13(5):551-8
Nature neuroscience 2010 May;13(5):551-8
Mago, a vertebrate homolog of Drosophila Mago nashi protein, is a component of the chromatoid body in the cytoplasm of the postmeiotic spermatid.
Zhao W, Zhou F, Zhou X, Hou Y, He Y, Cheng H, Zhou R
Journal of experimental zoology. Part B, Molecular and developmental evolution 2010 May 15;314(3):232-41
Journal of experimental zoology. Part B, Molecular and developmental evolution 2010 May 15;314(3):232-41
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 12347-1-AP(MAGOH antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-MAGOH (IP:12347-1-AP, 3ug; Detection:12347-1-AP 1:500) with K-562 cells lysate 2400ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MAGOH antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MAGOH. This antibody recognizes human antigen. The MAGOH antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
