HPA055945

antibody from Atlas Antibodies

Targeting: SLAMF7 19A, CD319, CRACC, CS1

Western blot (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

HPA055945

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA055945, RRID:AB_2682980

Product name

Anti-SLAMF7

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human SLAMF7, Gene description: SLAM family member 7, Alternative Gene Names: 19A, CD319, CRACC, CS1, Validated applications: IHC, WB, Uniprot ID: Q9NQ25, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Extrafollicular IgD−CD27−CXCR5−CD11c− DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19

Allard-Chamard H, Kaneko N, Bertocchi A, Sun N, Boucau J, Kuo H, Farmer J, Perugino C, Mahajan V, Murphy S, Premo K, Diefenbach T, Ghebremichael M, Yuen G, Kotta A, Akman Z, Lichterfeld M, Walker B, Yu X, Moriyama M, Maehara T, Nakamura S, Stone J, Padera R, Pillai S
Cell Reports 2023;42(6):112630

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Temporal changes in T cell subsets and expansion of cytotoxic CD4+ T cells in the lungs in severe COVID-19

Kaneko N, Boucau J, Kuo H, Perugino C, Mahajan V, Farmer J, Liu H, Diefenbach T, Piechocka-Trocha A, Lefteri K, Waring M, Premo K, Walker B, Li J, Gaiha G, Yu X, Lichterfeld M, Padera R, Pillai S
Clinical Immunology 2022;237

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CD4+ and CD8+ cytotoxic T lymphocytes may induce mesenchymal cell apoptosis in IgG4-related disease

Perugino C, Kaneko N, Maehara T, Mattoo H, Kers J, Allard-Chamard H, Mahajan V, Liu H, Della-Torre E, Murphy S, Ghebremichael M, Wallace Z, Bolster M, Harvey L, Mylvaganam G, Tuncay Y, Liang L, Montesi S, Zhang X, Tinju A, Mochizuki K, Munemura R, Sakamoto M, Moriyama M, Nakamura S, Yosef N, Stone J, Pillai S
Journal of Allergy and Clinical Immunology 2021;147(1):368-382

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Elotuzumab for the treatment of extramedullary myeloma: a retrospective analysis of clinical efficacy and SLAMF7 expression patterns

Danhof S, Rasche L, Mottok A, Steinmüller T, Zhou X, Schreder M, Kilian T, Strifler S, Rosenwald A, Hudecek M, Einsele H, Gerhard-Hartmann E
Annals of Hematology 2021;100(6):1537-1546

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Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis

Maehara T, Kaneko N, Perugino C, Mattoo H, Kers, J, Allard-Chamard H, Mahajan V, Liu H, Murphy S, Ghebremichael M, Fox D, Payne A, Lafyatis R, Stone J, Khanna D, Pillai S
Journal of Clinical Investigation 2020;130(5):2451-2464

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Enrichment of the tumour immune microenvironment in patients with desmoplastic colorectal liver metastasis

Höppener D, Nierop P, Hof J, Sideras K, Zhou G, Visser L, Gouw A, de Jong K, Sprengers D, Kwekkeboom J, Vermeulen P, Grünhagen D, Verhoef C
British Journal of Cancer 2020;123(2):196-206

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B Cells as Prognostic Biomarker After Surgery for Colorectal Liver Metastases.

Hof J, Visser L, Höppener DJ, Nierop PMH, Terpstra MM, Gouw ASH, Grünhagen DJ, Verhoef C, Sijmons RH, de Jong KP, Kok K
Frontiers in oncology 2020;10:249

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Orthogonal validation

Main image

Experimental details

Immunohistochemistry analysis in human tonsil and skeletal muscle tissues using HPA055945 antibody. Corresponding SLAMF7 RNA-seq data are presented for the same tissues.

Sample type

Human

Protocol

Protocol

Orthogonal method

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

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