331802

antibody from BioLegend

Targeting: SLAMF7 19A, CD319, CRACC, CS1

Immunoprecipitation (Recommended by provider)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

331802

Provider

BioLegend

Proper citation

BioLegend Cat#331802, RRID:AB_961330

Product name

Purified anti-human CD319 (CRACC)

Antibody type

Monoclonal

Antigen

CRACC-Human IgG1 fusion protein

Description

CD319 is a single-pass type-1 335 aa transmembrane glycoprotein and expressed on NK cells, subsets of mature dendritic cells, activated B cells, cytotoxic lymphocytes but not in promyelocytic, B- or T-cell lines. Expression is high in spleen, lymph node, periperal blood leukocytes and lowest in bone marrow. Expression is in small intestine, stomach, appendix, lung and trachea. CD319 is tyrosine phosphorylated in activated NK cells and is associated with 19- and 39 kD proteins. CD319 has a homology with the CD2 family of receptors within the Ig superfamily. Some of the CD2 members stimulate cytotoxicity through the CD319 associated protein.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µg

Concentration

0.5 mg/ml

Storage

The antibody solution should be stored undiluted at 4°C.