Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 331806 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#331806, RRID:AB_2239190
- Product name
- PE anti-human CD319 (CRACC)
- Antibody type
- Monoclonal
- Antigen
- CRACC-Human IgG1 fusion protein
- Description
- CD319 is a single-pass type-1 335 aa transmembrane glycoprotein and expressed on NK cells, subsets of mature dendritic cells, activated B cells, cytotoxic lymphocytes but not in promyelocytic, B- or T-cell lines. Expression is high in spleen, lymph node, periperal blood leukocytes and lowest in bone marrow. Expression is in small intestine, stomach, appendix, lung and trachea. CD319 is tyrosine phosphorylated in activated NK cells and is associated with 19- and 39 kD proteins. CD319 has a homology with the CD2 family of receptors within the Ig superfamily. Some of the CD2 members stimulate cytotoxicity through the CD319 associated protein.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human peripheral blood lymphocytes stained with CD3 (HIT3a APC) and 162.1 PE
- Conjugate
- Yellow dye