Antibody data
- Antibody Data
- Antigen structure
- References [29]
- Comments [0]
- Validations [0]
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- Product number
- 66304-1-Ig - Provider product page

- Provider
- Proteintech Group
- Product name
- CD47 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated CD47 antibody (Cat. #66304-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: FC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1E1D8
- Vial size
- 20ul, 150ul
Submitted references Macrophage-biomimetic nanomedicine for targeted therapy of abdominal aortic aneurysm via Nrf2/NF-κB pathway.
Metformin suppresses PPARδ-driven CD47 transcription to enhance macrophage phagocytosis in lung cancer.
Cancer cell membrane and iRGD peptide co-modified cantharidin liposomes for targeted therapy and immunotherapy of triple-negative breast cancer.
A pH-Responsive Biomimetic Antioxidant Nanoplatform with Dual Renal Targeting for Synergistic Therapy of Acute Kidney Injury.
Arsenic sulfide enhances the therapeutic effect of hepatocellular carcinoma immunotherapy through STAT3-THBS1/CD47 pathway.
Resolvin D2 limits senescent cell accumulation in atherosclerotic plaques.
TNAP-induced CD47 membrane expression enhances TGF-β1 conversion in liver fibrosis.
Host Cell Membrane-Cloaked Nanomedicine Reprograms Endothelial Surface for Enhanced Patency in Allogeneic Vascular Grafts.
Engineered macrophage membrane-coated nanoparticles attenuate calcium oxalate nephrocalcinosis-induced kidney injury by reducing oxidative stress and pyroptosis.
ROS Responsive Cerium Oxide Biomimetic Nanoparticles Alleviates Calcium Oxalate Crystals Induced Kidney Injury via Suppressing Oxidative Stress and M1 Macrophage Polarization.
CD47-targeted liposomal chemotherapy upregulates CD47 expression and induces microsatellite instability which enhances cancer immunotherapy.
Biomimetic Delivery of Cisplatin for Efficient Immunotherapy of Gasdermin E-Positive Hepatocellular Carcinoma via a Pt Concentration-Dependent Minimalist Pyroptosis Strategy.
Dual-Regulated Biomimetic Nanocomposites For Promoted Tumor Photodynamic Immunotherapy.
Bispecific Nanobody-Aptamer Conjugates for Enhanced Cancer Therapy in Solid Tumors.
Antibody nanoparticle conjugate-based targeted immunotherapy for non-small cell lung cancer.
Cancer cell membrane-camouflaged paclitaxel/PLGA nanoparticles for targeted therapy against lung cancer.
Restoration of miR-299-3p promotes efferocytosis and ameliorates atherosclerosis via repressing CD47 in mice.
Endothelial transferrin receptor 1 contributes to thrombogenesis through cascade ferroptosis.
Enterolactone and trabectedin suppress epithelial ovarian cancer synergistically via upregulating THBS1.
Platelet-mimetic nano-sensor for combating postoperative recurrence and wound infection of triple-negative breast cancer.
Long Circulating Cancer Cell-Targeted Bionic Nanocarriers Enable Synergistic Combinatorial Therapy in Colon Cancer.
Remodeling Collagen Microenvironment in Liver Using a Biomimetic Nano-Regulator for Reversal of Liver Fibrosis.
B7-H3 and CD47 co-expression in gastric cancer is a predictor of poor prognosis and potential targets for future dual-targeting immunotherapy.
CD47 interactions with exportin-1 limit the targeting of m(7)G-modified RNAs to extracellular vesicles.
Erythrocyte-biomimetic nanosystems to improve antitumor effects of paclitaxel on epithelial cancers.
Naturally Equipped Urinary Exosomes Coated Poly (2-ethyl-2-oxazoline)-Poly (D, L-lactide) Nanocarriers for the Pre-Clinical Translation of Breast Cancer.
Bone-targeted erythrocyte-cancer hybrid membrane-camouflaged nanoparticles for enhancing photothermal and hypoxia-activated chemotherapy of bone invasion by OSCC.
MicroRNA-148a-3p inhibits cancer progression and is a novel screening biomarker for gastric cancer.
Seedless preparation of Au nanorods by hydroquinone assistant and red blood cell membrane camouflage.
Luo Q, Meng W, Wang J, Zhang X, Meng Q, Hu M, Wei S, Yu X, Deng D, Zhang Y, Ma Z, Li S, Wang S, Zhang B, Ding J, Liu J, Zhou J
Theranostics 2026;16(7):3363-3383
Theranostics 2026;16(7):3363-3383
Metformin suppresses PPARδ-driven CD47 transcription to enhance macrophage phagocytosis in lung cancer.
Cui Q, Wang H, Yu H, Li Y, Wang Y, Shi J, Hou Y
The Journal of biological chemistry 2026 Mar;302(3):111159
The Journal of biological chemistry 2026 Mar;302(3):111159
Cancer cell membrane and iRGD peptide co-modified cantharidin liposomes for targeted therapy and immunotherapy of triple-negative breast cancer.
Guo Q, Wang S, Zhong Z, Zhou L, Xia X
Free radical biology & medicine 2026 Jun;249:273-291
Free radical biology & medicine 2026 Jun;249:273-291
A pH-Responsive Biomimetic Antioxidant Nanoplatform with Dual Renal Targeting for Synergistic Therapy of Acute Kidney Injury.
Zhang S, Xie Y, Zhang L, Qi Y, Liao Q, Xu C, Yang S, Zhou H, Tan Q, Qi S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e15664
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e15664
Arsenic sulfide enhances the therapeutic effect of hepatocellular carcinoma immunotherapy through STAT3-THBS1/CD47 pathway.
Kang T, Feng Z, Cai Y, Huang R, Wang R, Liu Z, Lu S, Xie S, Liu H, Chen S
Frontiers in immunology 2025;16:1612318
Frontiers in immunology 2025;16:1612318
Resolvin D2 limits senescent cell accumulation in atherosclerotic plaques.
Lipscomb M, Salfate Del Rio I, Eid M, Rahtes A, Martino G, Sadhu S, Khan S, MacNamara KC, Fredman G
Vascular pharmacology 2025 Sep;160:107527
Vascular pharmacology 2025 Sep;160:107527
TNAP-induced CD47 membrane expression enhances TGF-β1 conversion in liver fibrosis.
Gao L, Peng F, Qi P, Zhang H, Chi H, Deng L, Liang X, Sun M, Ma W, Yang C, Liu Q, Wei X, Li Y, Zhao J
Hepatology communications 2025 Oct 1;9(10)
Hepatology communications 2025 Oct 1;9(10)
Host Cell Membrane-Cloaked Nanomedicine Reprograms Endothelial Surface for Enhanced Patency in Allogeneic Vascular Grafts.
Pei J, Qin Y, Liu Q, Sun D, Qu X, Yang G, Yang D, Gao T, Liu Y, Sun H, Guo X, Xu Y, Fan Y, Zhu C
Advanced materials (Deerfield Beach, Fla.) 2025 Nov;37(44):e06653
Advanced materials (Deerfield Beach, Fla.) 2025 Nov;37(44):e06653
Engineered macrophage membrane-coated nanoparticles attenuate calcium oxalate nephrocalcinosis-induced kidney injury by reducing oxidative stress and pyroptosis.
Ba X, Ye T, He Y, Tong Y, Shang H, Wu J, Deng W, Zhong Z, Yang X, Wang K, Xie Y, Jiang K, Guo X, Tang K
Acta biomaterialia 2025 Mar 15;195:479-495
Acta biomaterialia 2025 Mar 15;195:479-495
ROS Responsive Cerium Oxide Biomimetic Nanoparticles Alleviates Calcium Oxalate Crystals Induced Kidney Injury via Suppressing Oxidative Stress and M1 Macrophage Polarization.
He Y, Peng E, Ba X, Wu J, Deng W, Huang Q, Tong Y, Shang H, Zhong Z, Liu X, Zhang Y, Ye T, Yang X, Wang K, Xie Y, Jiang K, Xia D, Chen Z, Tang K
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(3):e2405417
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(3):e2405417
CD47-targeted liposomal chemotherapy upregulates CD47 expression and induces microsatellite instability which enhances cancer immunotherapy.
Liu Q, Liang J, Gu Y, Gao H, Yang D, Jiang Y, Zhang J, Lei Q, Yang B
Journal of controlled release : official journal of the Controlled Release Society 2025 Dec 10;388(Pt 2):114351
Journal of controlled release : official journal of the Controlled Release Society 2025 Dec 10;388(Pt 2):114351
Biomimetic Delivery of Cisplatin for Efficient Immunotherapy of Gasdermin E-Positive Hepatocellular Carcinoma via a Pt Concentration-Dependent Minimalist Pyroptosis Strategy.
Huang Y, He S, Xu J, Zou T, Liu J, Huang C, Chen Y, Liu H, Lei A, Wei H, Yu CY
Advanced healthcare materials 2025 Aug;14(21):e2500766
Advanced healthcare materials 2025 Aug;14(21):e2500766
Dual-Regulated Biomimetic Nanocomposites For Promoted Tumor Photodynamic Immunotherapy.
Liao L, Liu Y, Li X, Jiang Z, Jiang Z, Yao J
ACS applied materials & interfaces 2025 Apr 9;17(14):20919-20931
ACS applied materials & interfaces 2025 Apr 9;17(14):20919-20931
Bispecific Nanobody-Aptamer Conjugates for Enhanced Cancer Therapy in Solid Tumors.
Wang Y, Chen J, Zhang S, Jiang H, Zhu J, Jiang G, Liu Y, Zhu Y, Li J
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(25):e2308265
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(25):e2308265
Antibody nanoparticle conjugate-based targeted immunotherapy for non-small cell lung cancer.
Saha T, Fojtů M, Nagar AV, Thurakkal L, Srinivasan BB, Mukherjee M, Sibiyon A, Aggarwal H, Samuel A, Dash C, Jang HL, Sengupta S
Science advances 2024 Jun 14;10(24):eadi2046
Science advances 2024 Jun 14;10(24):eadi2046
Cancer cell membrane-camouflaged paclitaxel/PLGA nanoparticles for targeted therapy against lung cancer.
Zhou J, Wan S, Wu Y, Hu H, Liu Y, Liao Z, Xu M, Wu J, Fan Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117102
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117102
Restoration of miR-299-3p promotes efferocytosis and ameliorates atherosclerosis via repressing CD47 in mice.
Zhu Y, Ren S, Huang H, Wu J, You X, Gao J, Ren Y, Wang R, Zhao W, Tan S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 15;38(15):e23857
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 15;38(15):e23857
Endothelial transferrin receptor 1 contributes to thrombogenesis through cascade ferroptosis.
Ma H, Huang Y, Tian W, Liu J, Yan X, Ma L, Lai J
Redox biology 2024 Apr;70:103041
Redox biology 2024 Apr;70:103041
Enterolactone and trabectedin suppress epithelial ovarian cancer synergistically via upregulating THBS1.
Zeng Z, Lin C, Zhang MC, Kossinna P, Wang P, Cao D, Wang J, Xu M, Wang X, Li Q, Xu X, Yang H, Zhu S, Liu GR, Xie K, Yang J, Luo Y, Wang Y, Zhang XH, Lin J, Chen H, Liu SL, Liu H
Phytotherapy research : PTR 2023 Oct;37(10):4722-4739
Phytotherapy research : PTR 2023 Oct;37(10):4722-4739
Platelet-mimetic nano-sensor for combating postoperative recurrence and wound infection of triple-negative breast cancer.
Liu Y, Qi Y, Chen C, Jin Y, Du S, Qiao J, Yao J
Journal of controlled release : official journal of the Controlled Release Society 2023 Oct;362:396-408
Journal of controlled release : official journal of the Controlled Release Society 2023 Oct;362:396-408
Long Circulating Cancer Cell-Targeted Bionic Nanocarriers Enable Synergistic Combinatorial Therapy in Colon Cancer.
Zheng Y, Guo W, Hu L, Xiao Z, Yang X, Cao Z, Cao J
ACS applied materials & interfaces 2023 May 17;15(19):22843-22853
ACS applied materials & interfaces 2023 May 17;15(19):22843-22853
Remodeling Collagen Microenvironment in Liver Using a Biomimetic Nano-Regulator for Reversal of Liver Fibrosis.
Liang Y, Wang J, Xu C, Han W, Wu S, Wu Y, Zhang J, Liu J, Zhang Z, Shi J, Zhang K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(18):e2300127
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(18):e2300127
B7-H3 and CD47 co-expression in gastric cancer is a predictor of poor prognosis and potential targets for future dual-targeting immunotherapy.
Chen S, Zhan S, Ding S, Zhang Q, Xuan H, Zhang X, Cao L
Journal of cancer research and clinical oncology 2023 Dec;149(18):16609-16621
Journal of cancer research and clinical oncology 2023 Dec;149(18):16609-16621
CD47 interactions with exportin-1 limit the targeting of m(7)G-modified RNAs to extracellular vesicles.
Kaur S, Saldana AC, Elkahloun AG, Petersen JD, Arakelyan A, Singh SP, Jenkins LM, Kuo B, Reginauld B, Jordan DG, Tran AD, Wu W, Zimmerberg J, Margolis L, Roberts DD
Journal of cell communication and signaling 2022 Sep;16(3):397-419
Journal of cell communication and signaling 2022 Sep;16(3):397-419
Erythrocyte-biomimetic nanosystems to improve antitumor effects of paclitaxel on epithelial cancers.
Song M, Dong S, An X, Zhang W, Shen N, Li Y, Guo C, Liu C, Li X, Chen S
Journal of controlled release : official journal of the Controlled Release Society 2022 May;345:744-754
Journal of controlled release : official journal of the Controlled Release Society 2022 May;345:744-754
Naturally Equipped Urinary Exosomes Coated Poly (2-ethyl-2-oxazoline)-Poly (D, L-lactide) Nanocarriers for the Pre-Clinical Translation of Breast Cancer.
Ni J, Mi Y, Wang B, Zhu Y, Ding Y, Ding Y, Li X
Bioengineering (Basel, Switzerland) 2022 Aug 3;9(8)
Bioengineering (Basel, Switzerland) 2022 Aug 3;9(8)
Bone-targeted erythrocyte-cancer hybrid membrane-camouflaged nanoparticles for enhancing photothermal and hypoxia-activated chemotherapy of bone invasion by OSCC.
Chen H, Deng J, Yao X, He Y, Li H, Jian Z, Tang Y, Zhang X, Zhang J, Dai H
Journal of nanobiotechnology 2021 Oct 26;19(1):342
Journal of nanobiotechnology 2021 Oct 26;19(1):342
MicroRNA-148a-3p inhibits cancer progression and is a novel screening biomarker for gastric cancer.
Bao C, Guo L
Journal of clinical laboratory analysis 2020 Oct;34(10):e23454
Journal of clinical laboratory analysis 2020 Oct;34(10):e23454
Seedless preparation of Au nanorods by hydroquinone assistant and red blood cell membrane camouflage.
Li J, Wang W, Zhang X, Yao H, Wei Z, Li X, Mu X, Jiang J, Zhang H
RSC advances 2018 Jun 8;8(38):21316-21325
RSC advances 2018 Jun 8;8(38):21316-21325
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