Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14572-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14572-1-AP, RRID:AB_2271424
- Product name
- TFAP2C antibody
- Antibody type
- Polyclonal
- Description
- TFAP2C antibody (Cat. #14572-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TFAP2C Activates CST1 Transcription to Facilitate Breast Cancer Progression and Suppress Ferroptosis.
Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment.
TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling.
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer.
TFAP2C regulates carbonic anhydrase XII in human breast cancer.
Abrogation of glutathione peroxidase-1 drives EMT and chemoresistance in pancreatic cancer by activating ROS-mediated Akt/GSK3β/Snail signaling.
Yuan L, Zhou D, Li W, Guan J, Li J, Xu B
Biochemical genetics 2024 Oct;62(5):3858-3875
Biochemical genetics 2024 Oct;62(5):3858-3875
Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment.
Lu X, Luo Y, Nie X, Zhang B, Wang X, Li R, Liu G, Zhou Q, Liu Z, Fan L, Hotaling JM, Zhang Z, Bo H, Guo J
Nature communications 2023 Dec 20;14(1):8462
Nature communications 2023 Dec 20;14(1):8462
TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling.
Jiang X, Guo S, Xu M, Ma B, Liu R, Xu Y, Zhang Y
Frontiers in oncology 2022;12:862015
Frontiers in oncology 2022;12:862015
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
Xing J, Chen W, Chen K, Zhu S, Lin F, Qi Y, Zhang Y, Han S, Rao T, Ruan Y, Zhao S, Yu W, Cheng F
Cancers 2022 Sep 30;14(19)
Cancers 2022 Sep 30;14(19)
CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer.
Jiang T, Wang H, Liu L, Song H, Zhang Y, Wang J, Liu L, Xu T, Fan R, Xu Y, Wang S, Shi L, Zheng L, Wang R, Song J
Molecular cancer 2021 Dec 18;20(1):167
Molecular cancer 2021 Dec 18;20(1):167
TFAP2C regulates carbonic anhydrase XII in human breast cancer.
Franke CM, Gu VW, Grimm BG, Cassady VC, White JR, Weigel RJ, Kulak MV
Oncogene 2020 Feb;39(6):1290-1301
Oncogene 2020 Feb;39(6):1290-1301
Abrogation of glutathione peroxidase-1 drives EMT and chemoresistance in pancreatic cancer by activating ROS-mediated Akt/GSK3β/Snail signaling.
Meng Q, Shi S, Liang C, Liang D, Hua J, Zhang B, Xu J, Yu X
Oncogene 2018 Nov;37(44):5843-5857
Oncogene 2018 Nov;37(44):5843-5857
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14572-1-AP(TFAP2C antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 14572-1-AP(TFAP2C antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TFAP2C antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TFAP2C. This antibody recognizes human, mouse, rat antigen. The TFAP2C antibody has been validated for the following applications: ELISA, WB, IHC analysis.