Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APG01029G - Provider product page
- Provider
- Leading Biology
- Product name
- TFAP2C / AP2 Gamma Antibody (C-Terminus)
- Antibody type
- Polyclonal
- Description
- Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
- Reactivity
- Human, Rabbit, Simian
- Host
- Goat
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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