Antibody data
- Antibody Data
- Antigen structure
- References [64]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
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- Product number
- 20578-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20578-1-AP, RRID:AB_10732938
- Product name
- APOB antibody
- Antibody type
- Polyclonal
- Description
- APOB antibody (Cat. #20578-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Immune cells regulate circulating adipocyte extracellular vesicle levels in response to metabolic shifts.
Amelioration of hepatic steatosis in male obese rats by high-protein diet is dependent upon protein source.
Rab2A modulates liver fibroblast growth factor 21 (FGF21) expression and systemic metabolism via apolipoprotein B-CREBH signaling.
Identification of differentially expressed genes associated with tracheal injury recovery in a rabbit model of septic shock.
CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis.
Betaine decreases hepatic lipid deposition through DNA 5 mC and RNA m(6)A methylation-mediated regulation of fatty acid metabolic genes expression in laying hens.
Engineering of an Exosome-Based GPIHBP1 mRNA Delivery System for Efficient Therapy of Familial Hypertriglyceridemia.
Loss of hepatic carboxylesterase 3 prevents the development of MASLD in mice.
Lipoprotein Association Fluorometry (LAF) as a Semi-Quantitative Characterization Tool to Assess Extracellular Vesicle-Lipoprotein Binding.
Apolipoprotein B100 acts as a tumor suppressor in ovarian cancer via lipid/ER stress axis-induced blockade of autophagy.
Inducible global knockout of surfeit locus protein 4 in adult mice results in hypolipidemia, intestinal lipid accumulation, liver injury, and increased mortality.
Prevotella copri-produced 5-aminopentanoic acid promotes pediatric metabolic dysfunction-associated steatotic liver disease.
Rbm39 ameliorates metabolic dysfunction-associated steatotic liver disease by regulating Apob and Fabp4.
Hepatic AhR Activation by TCDD Induces Obesity and Steatosis via Hepatic Plasminogen Activator Inhibitor-1 (PAI-1).
Solanum lyratum-Derived Solalyraine A1 Suppresses Non-Small Cell Lung Cancer Through Regulation of Exosome Secretion and Related Protein Biomarkers.
Development of an Effective Isolation Method for Plasma Extracellular Vesicles Excluding Lipoproteins by Precipitation With Polyethylene Glycol.
HNF4A-Bridging the Gap Between Intestinal Metaplasia and Gastric Cancer.
Ethanol extract of Polygonatum cyrtonema Hua mitigates non-alcoholic steatohepatitis in mice.
Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation.
Naringenin inhibits the microsomal triglyceridetransfer protein/apolipoprotein B axis to inhibit intestinal metaplasia progression.
The trajectory of vesicular proteomic signatures from HBV-HCC by chitosan-magnetic bead-based separation and DIA-proteomic analysis.
Lipoproteins and Exosomes as Novel Carriers of Soluble Fms-Like Tyrosine Kinase-1 and Placental Growth Factor During Pregnancy.
Macrophage-derived FGFR1 drives atherosclerosis through PLCγ-mediated activation of NF-κB inflammatory signalling pathway.
Identification of disease-specific extracellular vesicle-associated plasma protein biomarkers for Duchenne Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy.
Apolipoprotein B Secretion Assay from Primary Hepatocytes.
Leukocyte immunoglobulin-like receptor B1 (LILRB1) protects human multiple myeloma cells from ferroptosis by maintaining cholesterol homeostasis.
Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes.
In situ customized apolipoprotein B48-enriched protein corona enhances oral gene delivery of chitosan-based nanoparticles.
Extracellular vesicle-encapsulated miR-30c-5p reduces aging-related liver fibrosis.
C9orf72 controls hepatic lipid metabolism by regulating SREBP1 transport.
Comparison of proteomic landscape of extracellular vesicles in pleural effusions isolated by three strategies.
Mechanical injury accentuates lipid deposition in ApoE(-/-) mice and advance aortic valve stenosis: A novel modified aortic valve stenosis model.
Metabolic characteristics of voriconazole - Induced liver injury in rats.
Long-term and liver-selected ginsenoside C-K nanoparticles retard NAFLD progression by restoring lipid homeostasis.
Discovery of lipid profiles in plasma-derived extracellular vesicles as biomarkers for breast cancer diagnosis.
Inflammatory Cell-Derived MYDGF Attenuates Endothelial LDL Transcytosis to Protect Against Atherogenesis.
Manganese regulation of COPII condensation controls circulating lipid homeostasis.
CM3-SII polysaccharide obtained from Cordyceps militaris ameliorates hyperlipidemia in heterozygous LDLR-deficient hamsters by modulating gut microbiota and NPC1L1 and PPARα levels.
Si-Ni-San reverses dietary fat absorption defects in a murine model of depression.
Fenofibrate enhances lipid deposition via modulating PPARγ, SREBP-1c, and gut microbiota in ob/ob mice fed a high-fat diet.
Characteristics of Exosomes and the Vascular Landscape Regulate Exosome Sequestration by Peripheral Tissues and Brain.
Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice.
The Cordyceps militaris-Derived Polysaccharide CM1 Alleviates Atherosclerosis in LDLR((-/-)) Mice by Improving Hyperlipidemia.
Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding.
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
Quantitative proteomics of plasma and liver reveals the mechanism of turmeric in preventing hyperlipidemia in mice.
The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions.
Enterically derived high-density lipoprotein restrains liver injury through the portal vein.
Celastrol inhibits intestinal lipid absorption by reprofiling the gut microbiota to attenuate high-fat diet-induced obesity.
Polysaccharide CM1 from Cordyceps militaris hinders adipocyte differentiation and alleviates hyperlipidemia in LDLR((+/-)) hamsters.
GP73 is a TBC-domain Rab GTPase-activating protein contributing to the pathogenesis of non-alcoholic fatty liver disease without obesity.
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
MD2 blockade prevents modified LDL-induced retinal injury in diabetes by suppressing NADPH oxidase-4 interaction with Toll-like receptor-4.
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Comprehensive lipidomics in apoM(-/-) mice reveals an overall state of metabolic distress and attenuated hepatic lipid secretion into the circulation.
Effect and mechanism of ginsenoside Rg1-regulating hepatic steatosis in HepG2 cells induced by free fatty acid.
Macrophage-derived myeloid differentiation protein 2 plays an essential role in ox-LDL-induced inflammation and atherosclerosis.
Small sequence variations between two mammalian paralogs of the small GTPase SAR1 underlie functional differences in coat protein complex II assembly.
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Downregulation of GNAI3 Promotes the Pathogenesis of Methionine/Choline-Deficient Diet-Induced Nonalcoholic Fatty Liver Disease.
Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine.
Hepatic loss of Lissencephaly 1 (Lis1) induces fatty liver and accelerates liver tumorigenesis in mice.
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Rab8a Deficiency in Skeletal Muscle Causes Hyperlipidemia and Hepatosteatosis by Impairing Muscle Lipid Uptake and Storage.
Tiash S, Patel SA, Russo M, Suresh A, Pang B, Pai YL, Jia W, Field RL, Pietka T, Abumrad NA, Smith GI, Samovski D, Klein S, Brestoff JR, Crewe C
Cell metabolism 2026 May 5;38(5):929-943.e8
Cell metabolism 2026 May 5;38(5):929-943.e8
Amelioration of hepatic steatosis in male obese rats by high-protein diet is dependent upon protein source.
Ramadan FHJ, Zahradka P, Taylor CG
The Journal of nutritional biochemistry 2026 Jul;153:110310
The Journal of nutritional biochemistry 2026 Jul;153:110310
Rab2A modulates liver fibroblast growth factor 21 (FGF21) expression and systemic metabolism via apolipoprotein B-CREBH signaling.
Chen ZY, Xu M, Chen S, Chen L
The Journal of biological chemistry 2026 Jan;302(1):110977
The Journal of biological chemistry 2026 Jan;302(1):110977
Identification of differentially expressed genes associated with tracheal injury recovery in a rabbit model of septic shock.
Zhang P, Lu H, Li X, Tian Y, Tian W, Ma S, Liu C, Liu X, Huang L
BMC medical genomics 2026 Jan 7;19(1)
BMC medical genomics 2026 Jan 7;19(1)
CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis.
Wu L, Wang J, Wang Y, Yang J, Yao Y, Wang Y, Huang D, Hu Y, Xu X, Wang R, Du W, Shi Y, Li Q, Liu L, Zhu Y, Li S, Chen FJ, Zhang X, Wang X, Guo Q, Xu L, Li P, Chen XW
Nature 2026 Apr;652(8109):471-480
Nature 2026 Apr;652(8109):471-480
Betaine decreases hepatic lipid deposition through DNA 5 mC and RNA m(6)A methylation-mediated regulation of fatty acid metabolic genes expression in laying hens.
Yang Y, Jin X, Lu D, Wu Y, Meng F, Zhang M, Wang J, Cui X, Li T, Wang S, Luo X, Hu Y
Poultry science 2025 Sep;104(9):105496
Poultry science 2025 Sep;104(9):105496
Engineering of an Exosome-Based GPIHBP1 mRNA Delivery System for Efficient Therapy of Familial Hypertriglyceridemia.
Cao Y, Meng X, Xu X, Xia C, Yang C, Cui X, He Q, Song G
Journal of medicinal chemistry 2025 Sep 25;68(18):19554-19566
Journal of medicinal chemistry 2025 Sep 25;68(18):19554-19566
Loss of hepatic carboxylesterase 3 prevents the development of MASLD in mice.
Batayneh Z, Pan X, Gopoju R, Hu S, Chen S, Wang J, Wang H, Gunawardana L, Kasumov T, Zhang Y
Journal of lipid research 2025 Oct;66(10):100887
Journal of lipid research 2025 Oct;66(10):100887
Lipoprotein Association Fluorometry (LAF) as a Semi-Quantitative Characterization Tool to Assess Extracellular Vesicle-Lipoprotein Binding.
Ghebosu R, Goncalves JP, Fitri NI, Iannotta D, Sharifpour MF, Coleborn E, Loukas A, Souza-Fonseca-Guimaraes F, Wolfram J
Journal of extracellular vesicles 2025 Oct;14(10):e70172
Journal of extracellular vesicles 2025 Oct;14(10):e70172
Apolipoprotein B100 acts as a tumor suppressor in ovarian cancer via lipid/ER stress axis-induced blockade of autophagy.
Yin ZY, He SM, Zhang XY, Yu XC, Sheng KX, Fu T, Jiang YX, Xu L, Hu BX, Zhang JB, Li YY, Wang Q, Zhang BB, Qi YM, Adu-Amankwaah J, Zhou XY, Qi Q, Zhang B, Li CL
Acta pharmacologica Sinica 2025 May;46(5):1445-1461
Acta pharmacologica Sinica 2025 May;46(5):1445-1461
Inducible global knockout of surfeit locus protein 4 in adult mice results in hypolipidemia, intestinal lipid accumulation, liver injury, and increased mortality.
Chen W, Chen Y, Song B, Zhai L, Tao G, Wang B, Liu B, Wang H, Zhang CX, Gu HM, Yin D, Qin S, Zhang DW
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Mar;1870(2):159577
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Mar;1870(2):159577
Prevotella copri-produced 5-aminopentanoic acid promotes pediatric metabolic dysfunction-associated steatotic liver disease.
Xu QY, Ren TY, Zhou YC, Xu J, Du LD, Hong DY, Zhang QR, Chu HK, Peng Z, Fan JG, Jiang L
Hepatobiliary & pancreatic diseases international : HBPD INT 2025 Jun;24(3):303-315
Hepatobiliary & pancreatic diseases international : HBPD INT 2025 Jun;24(3):303-315
Rbm39 ameliorates metabolic dysfunction-associated steatotic liver disease by regulating Apob and Fabp4.
Zhuang C, Cui F, Chen J, He D, Sun T, Wang P
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167815
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167815
Hepatic AhR Activation by TCDD Induces Obesity and Steatosis via Hepatic Plasminogen Activator Inhibitor-1 (PAI-1).
Oh SJ, Im S, Kang S, Lee AG, Lee BC, Pak YK
International journal of molecular sciences 2025 Aug 30;26(17)
International journal of molecular sciences 2025 Aug 30;26(17)
Solanum lyratum-Derived Solalyraine A1 Suppresses Non-Small Cell Lung Cancer Through Regulation of Exosome Secretion and Related Protein Biomarkers.
Jiang P, Liu L, Chen L, Han B, Du X
Pharmaceuticals (Basel, Switzerland) 2025 Aug 27;18(9)
Pharmaceuticals (Basel, Switzerland) 2025 Aug 27;18(9)
Development of an Effective Isolation Method for Plasma Extracellular Vesicles Excluding Lipoproteins by Precipitation With Polyethylene Glycol.
Otani K, Fujioka Y, Okada M, Yamawaki H
Journal of extracellular biology 2025 Apr;4(4):e70047
Journal of extracellular biology 2025 Apr;4(4):e70047
HNF4A-Bridging the Gap Between Intestinal Metaplasia and Gastric Cancer.
Zhao Y, Tang H, Xu J, Sun F, Zhao Y, Li Y
Evolutionary bioinformatics online 2024;20:11769343241249017
Evolutionary bioinformatics online 2024;20:11769343241249017
Ethanol extract of Polygonatum cyrtonema Hua mitigates non-alcoholic steatohepatitis in mice.
Chen D, Shen Y, Huang F, Huang B, Xu S, Li L, Liu J, Li Z, Li X
Frontiers in pharmacology 2024;15:1487738
Frontiers in pharmacology 2024;15:1487738
Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation.
Zhang LW, Zhu LL, Zhu XY, Fu SQ, Liu XM
Frontiers in pharmacology 2024;15:1337057
Frontiers in pharmacology 2024;15:1337057
Naringenin inhibits the microsomal triglyceridetransfer protein/apolipoprotein B axis to inhibit intestinal metaplasia progression.
Huang X, Zhang M, Gu L, Zhou Z, Shi S, Fan X, Tong W, Liu D, Fang J, Huang X, Fang Z, Lu M
Phytotherapy research : PTR 2024 Sep;38(9):4541-4554
Phytotherapy research : PTR 2024 Sep;38(9):4541-4554
The trajectory of vesicular proteomic signatures from HBV-HCC by chitosan-magnetic bead-based separation and DIA-proteomic analysis.
Cao L, Zhou Y, Lin S, Yang C, Guan Z, Li X, Yang S, Gao T, Zhao J, Fan N, Song Y, Li D, Li X, Li Z, Guan F, Tan Z
Journal of extracellular vesicles 2024 Sep;13(9):e12499
Journal of extracellular vesicles 2024 Sep;13(9):e12499
Lipoproteins and Exosomes as Novel Carriers of Soluble Fms-Like Tyrosine Kinase-1 and Placental Growth Factor During Pregnancy.
Tan L, van Heugten MH, Kluivers ACM, van Vark-van der Zee L, Mulder MT, Lu X, Danser AHJ, Verdonk K
Hypertension (Dallas, Tex. : 1979) 2024 Oct;81(10):e132-e134
Hypertension (Dallas, Tex. : 1979) 2024 Oct;81(10):e132-e134
Macrophage-derived FGFR1 drives atherosclerosis through PLCγ-mediated activation of NF-κB inflammatory signalling pathway.
Wang L, Luo W, Zhang S, Zhang J, He L, Shi Y, Gao L, Wu B, Nie X, Hu C, Han X, He C, Xu B, Liang G
Cardiovascular research 2024 Oct 14;120(12):1385-1399
Cardiovascular research 2024 Oct 14;120(12):1385-1399
Identification of disease-specific extracellular vesicle-associated plasma protein biomarkers for Duchenne Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy.
Bayazit MB, Henderson D, Nguyen KT, Reátegui E, Tawil R, Flanigan KM, Harper SQ, Saad NY
medRxiv : the preprint server for health sciences 2024 Nov 30;
medRxiv : the preprint server for health sciences 2024 Nov 30;
Apolipoprotein B Secretion Assay from Primary Hepatocytes.
Wang Y, Li X, Huang R, Chen XW, Wang X
Bio-protocol 2024 May 5;14(9):e4982
Bio-protocol 2024 May 5;14(9):e4982
Leukocyte immunoglobulin-like receptor B1 (LILRB1) protects human multiple myeloma cells from ferroptosis by maintaining cholesterol homeostasis.
Xian M, Wang Q, Xiao L, Zhong L, Xiong W, Ye L, Su P, Zhang C, Li Y, Orlowski RZ, Zhan F, Ganguly S, Zu Y, Qian J, Yi Q
Nature communications 2024 Jul 9;15(1):5767
Nature communications 2024 Jul 9;15(1):5767
Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes.
Xu M, Chen ZY, Li Y, Li Y, Guo G, Dai RZ, Ni N, Tao J, Wang HY, Chen QL, Wang H, Zhou H, Yang YN, Chen S, Chen L
The EMBO journal 2024 Dec;43(24):6383-6409
The EMBO journal 2024 Dec;43(24):6383-6409
In situ customized apolipoprotein B48-enriched protein corona enhances oral gene delivery of chitosan-based nanoparticles.
Lin Z, Li S, Wu Q, Qu H, Shi X, Wang K, Tang C, Yin C
Biomaterials 2024 Dec;311:122704
Biomaterials 2024 Dec;311:122704
Extracellular vesicle-encapsulated miR-30c-5p reduces aging-related liver fibrosis.
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Aging cell 2024 Dec;23(12):e14310
C9orf72 controls hepatic lipid metabolism by regulating SREBP1 transport.
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Cell death and differentiation 2024 Aug;31(8):1070-1084
Cell death and differentiation 2024 Aug;31(8):1070-1084
Comparison of proteomic landscape of extracellular vesicles in pleural effusions isolated by three strategies.
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Frontiers in bioengineering and biotechnology 2023;11:1108952
Frontiers in bioengineering and biotechnology 2023;11:1108952
Mechanical injury accentuates lipid deposition in ApoE(-/-) mice and advance aortic valve stenosis: A novel modified aortic valve stenosis model.
Wen D, Hu L, Shan J, Zhang H, Hu L, Yuan A, Pu J, Xue S
Frontiers in cardiovascular medicine 2023;10:1119746
Frontiers in cardiovascular medicine 2023;10:1119746
Metabolic characteristics of voriconazole - Induced liver injury in rats.
Du Q, Teng M, Yang L, Meng C, Qiu Y, Wang C, Chen J, Wang T, Chen S, Luo Y, Sun J, Dong Y
Chemico-biological interactions 2023 Sep 25;383:110693
Chemico-biological interactions 2023 Sep 25;383:110693
Long-term and liver-selected ginsenoside C-K nanoparticles retard NAFLD progression by restoring lipid homeostasis.
Yue C, Li D, Fan S, Tao F, Yu Y, Lu W, Chen Q, Yuan A, Wu J, Zhao G, Dong H, Hu Y
Biomaterials 2023 Oct;301:122291
Biomaterials 2023 Oct;301:122291
Discovery of lipid profiles in plasma-derived extracellular vesicles as biomarkers for breast cancer diagnosis.
Liu L, Kawashima M, Sugimoto M, Sonomura K, Pu F, Li W, Takeda M, Goto T, Kawaguchi K, Sato TA, Toi M
Cancer science 2023 Oct;114(10):4020-4031
Cancer science 2023 Oct;114(10):4020-4031
Inflammatory Cell-Derived MYDGF Attenuates Endothelial LDL Transcytosis to Protect Against Atherogenesis.
Xu J, Ma H, Shi L, Zhou H, Cheng Y, Tong J, Meng B, Xu X, He K, Ding S, Zhang J, Yue L, Xiang G
Arteriosclerosis, thrombosis, and vascular biology 2023 Nov;43(11):e443-e467
Arteriosclerosis, thrombosis, and vascular biology 2023 Nov;43(11):e443-e467
Manganese regulation of COPII condensation controls circulating lipid homeostasis.
Wang X, Huang R, Wang Y, Zhou W, Hu Y, Yao Y, Cheng K, Li X, Xu B, Zhang J, Xu Y, Zeng F, Zhu Y, Chen XW
Nature cell biology 2023 Nov;25(11):1650-1663
Nature cell biology 2023 Nov;25(11):1650-1663
CM3-SII polysaccharide obtained from Cordyceps militaris ameliorates hyperlipidemia in heterozygous LDLR-deficient hamsters by modulating gut microbiota and NPC1L1 and PPARα levels.
Yu WQ, Wang XL, Ji HH, Miao M, Zhang BH, Li H, Zhang ZY, Ji CF, Guo SD
International journal of biological macromolecules 2023 Jun 1;239:124293
International journal of biological macromolecules 2023 Jun 1;239:124293
Si-Ni-San reverses dietary fat absorption defects in a murine model of depression.
Liu Y, Lv B, Tang K, Qu H, Yu F, Shi Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115677
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115677
Fenofibrate enhances lipid deposition via modulating PPARγ, SREBP-1c, and gut microbiota in ob/ob mice fed a high-fat diet.
Zhang Y, Jia XB, Liu YC, Yu WQ, Si YH, Guo SD
Frontiers in nutrition 2022;9:971581
Frontiers in nutrition 2022;9:971581
Characteristics of Exosomes and the Vascular Landscape Regulate Exosome Sequestration by Peripheral Tissues and Brain.
Banks WA, Sharma P, Hansen KM, Ludwig N, Whiteside TL
International journal of molecular sciences 2022 Oct 19;23(20)
International journal of molecular sciences 2022 Oct 19;23(20)
Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice.
Paterson HAB, Yu S, Artigas N, Prado MA, Haberman N, Wang YF, Jobbins AM, Pahita E, Mokochinski J, Hall Z, Guerin M, Paulo JA, Ng SS, Villarroya F, Rashid ST, Le Goff W, Lenhard B, Cebola I, Finley D, Gygi SP, Sibley CR, Vernia S
Nature metabolism 2022 Dec;4(12):1812-1829
Nature metabolism 2022 Dec;4(12):1812-1829
The Cordyceps militaris-Derived Polysaccharide CM1 Alleviates Atherosclerosis in LDLR((-/-)) Mice by Improving Hyperlipidemia.
Yin F, Lin P, Yu WQ, Shen N, Li Y, Guo SD
Frontiers in molecular biosciences 2021;8:783807
Frontiers in molecular biosciences 2021;8:783807
Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding.
Yu F, Wang Z, Zhang T, Chen X, Xu H, Wang F, Guo L, Chen M, Liu K, Wu B
Nature communications 2021 Sep 7;12(1):5323
Nature communications 2021 Sep 7;12(1):5323
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
Song M, Zhang S, Tao Z, Li J, Shi Y, Xiong Y, Zhang W, Liu C, Chen S
Biomaterials 2021 Nov;278:121183
Biomaterials 2021 Nov;278:121183
Quantitative proteomics of plasma and liver reveals the mechanism of turmeric in preventing hyperlipidemia in mice.
Wang M, Wang R, Li L, Yan Y, Jia S, Jiang H, Du Z
Food & function 2021 Nov 1;12(21):10484-10499
Food & function 2021 Nov 1;12(21):10484-10499
The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions.
Tian S, Cao Y, Wang J, Bi Y, Zhong J, Meng X, Sun W, Yang R, Gan L, Wang X, Li H, Wang R
Scientific reports 2021 May 18;11(1):10548
Scientific reports 2021 May 18;11(1):10548
Enterically derived high-density lipoprotein restrains liver injury through the portal vein.
Han YH, Onufer EJ, Huang LH, Sprung RW, Davidson WS, Czepielewski RS, Wohltmann M, Sorci-Thomas MG, Warner BW, Randolph GJ
Science (New York, N.Y.) 2021 Jul 23;373(6553)
Science (New York, N.Y.) 2021 Jul 23;373(6553)
Celastrol inhibits intestinal lipid absorption by reprofiling the gut microbiota to attenuate high-fat diet-induced obesity.
Hua H, Zhang Y, Zhao F, Chen K, Wu T, Liu Q, Huang S, Zhang A, Jia Z
iScience 2021 Feb 19;24(2):102077
iScience 2021 Feb 19;24(2):102077
Polysaccharide CM1 from Cordyceps militaris hinders adipocyte differentiation and alleviates hyperlipidemia in LDLR((+/-)) hamsters.
Yu WQ, Yin F, Shen N, Lin P, Xia B, Li YJ, Guo SD
Lipids in health and disease 2021 Dec 13;20(1):178
Lipids in health and disease 2021 Dec 13;20(1):178
GP73 is a TBC-domain Rab GTPase-activating protein contributing to the pathogenesis of non-alcoholic fatty liver disease without obesity.
Peng Y, Zeng Q, Wan L, Ma E, Li H, Yang X, Zhang Y, Huang L, Lin H, Feng J, Xu Y, Li J, Liu M, Liu J, Lin C, Sun Z, Cheng G, Zhang X, Liu J, Li D, Wei M, Mo Y, Mu X, Deng X, Zhang D, Dong S, Huang H, Fang Y, Gao Q, Yang X, Wu F, Zhong H, Wei C
Nature communications 2021 Dec 1;12(1):7004
Nature communications 2021 Dec 1;12(1):7004
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
Huang D, Xu B, Liu L, Wu L, Zhu Y, Ghanbarpour A, Wang Y, Chen FJ, Lyu J, Hu Y, Kang Y, Zhou W, Wang X, Ding W, Li X, Jiang Z, Chen J, Zhang X, Zhou H, Li JZ, Guo C, Zheng W, Zhang X, Li P, Melia T, Reinisch K, Chen XW
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8
MD2 blockade prevents modified LDL-induced retinal injury in diabetes by suppressing NADPH oxidase-4 interaction with Toll-like receptor-4.
Chen H, Yan T, Song Z, Ying S, Wu B, Ju X, Yang X, Qu J, Wu W, Zhang Z, Wang Y
Experimental & molecular medicine 2021 Apr;53(4):681-694
Experimental & molecular medicine 2021 Apr;53(4):681-694
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Zhang K, Dong C, Chen M, Yang T, Wang X, Gao Y, Wang L, Wen Y, Chen G, Wang X, Yu X, Zhang Y, Wang P, Shang M, Han K, Zhou Y
Theranostics 2020;10(1):411-425
Theranostics 2020;10(1):411-425
Comprehensive lipidomics in apoM(-/-) mice reveals an overall state of metabolic distress and attenuated hepatic lipid secretion into the circulation.
Shi Y, Lam SM, Liu H, Luo G, Zhang J, Yao S, Li J, Zheng L, Xu N, Zhang X, Shui G
Journal of genetics and genomics = Yi chuan xue bao 2020 Sep 20;47(9):523-534
Journal of genetics and genomics = Yi chuan xue bao 2020 Sep 20;47(9):523-534
Effect and mechanism of ginsenoside Rg1-regulating hepatic steatosis in HepG2 cells induced by free fatty acid.
Gao Y, Zhang S, Li J, Zhao J, Xiao Q, Zhu Y, Zhang J, Huang W
Bioscience, biotechnology, and biochemistry 2020 Nov;84(11):2228-2240
Bioscience, biotechnology, and biochemistry 2020 Nov;84(11):2228-2240
Macrophage-derived myeloid differentiation protein 2 plays an essential role in ox-LDL-induced inflammation and atherosclerosis.
Chen T, Huang W, Qian J, Luo W, Shan P, Cai Y, Lin K, Wu G, Liang G
EBioMedicine 2020 Mar;53:102706
EBioMedicine 2020 Mar;53:102706
Small sequence variations between two mammalian paralogs of the small GTPase SAR1 underlie functional differences in coat protein complex II assembly.
Melville DB, Studer S, Schekman R
The Journal of biological chemistry 2020 Jun 19;295(25):8401-8412
The Journal of biological chemistry 2020 Jun 19;295(25):8401-8412
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Zhang Z, Zong C, Jiang M, Hu H, Cheng X, Ni J, Yi X, Jiang B, Tian F, Chang MW, Su W, Zhu L, Li J, Xiang X, Miao C, Gorospe M, de Cabo R, Dou Y, Ju Z, Yang J, Jiang C, Yang Z, Wang W
Nature communications 2020 Jun 16;11(1):3067
Nature communications 2020 Jun 16;11(1):3067
Downregulation of GNAI3 Promotes the Pathogenesis of Methionine/Choline-Deficient Diet-Induced Nonalcoholic Fatty Liver Disease.
Zhu H, Ge K, Lu J, Jia C
Gut and liver 2020 Jul 15;14(4):492-499
Gut and liver 2020 Jul 15;14(4):492-499
Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine.
Wang Y, Song W, Wang J, Wang T, Xiong X, Qi Z, Fu W, Yang X, Chen YG
The Journal of experimental medicine 2020 Feb 3;217(2)
The Journal of experimental medicine 2020 Feb 3;217(2)
Hepatic loss of Lissencephaly 1 (Lis1) induces fatty liver and accelerates liver tumorigenesis in mice.
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 20578-1-AP(APOB antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The APOB antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human APOB. This antibody recognizes human, mouse antigen. The APOB antibody has been validated for the following applications: ELISA, WB, IHC analysis.