FNab09488

antibody from FineTest Biotech

Targeting: WDR24 C16orf21, DKFZp434F054, JFP7

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

FNab09488

Provider

FineTest Biotech

Product name

WDR24 antibody

Antibody type

Polyclonal

Antigen

Recombinant protein fragment

Description

As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2(PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux(PubMed:27166823).

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

WD repeat domain 24


Epitope

IgG

Isotype

IgG

Vial size

100¦Ìg

Concentration

Immunogen affinity purified

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

Handling

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)