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LearnABIN152357
antibody from antibodies-online
Targeting: CELF1
BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, hNab50, NAB50, NAPOR
Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN152357 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-CUGBP, Elav-Like Family Member 1 (CELF1) antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse, Rat, Bovine, Porcine, Rabbit, Simian
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 3B1
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Smaug/SAMD4A restores translational activity of CUGBP1 and suppresses CUG-induced myopathy.
Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia.
CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1.
Ectopic expression of CGG containing mRNA is neurotoxic in mammals.
Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy.
Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice.
Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy.
Nuclear RNA foci in the heart in myotonic dystrophy.
Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2.
Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy.
A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator.
de Haro M, Al-Ramahi I, Jones KR, Holth JK, Timchenko LT, Botas J
PLoS genetics 2013 Apr;9(4):e1003445
PLoS genetics 2013 Apr;9(4):e1003445
Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia.
Xiao Q, Ford AL, Xu J, Yan P, Lee KY, Gonzales E, West T, Holtzman DM, Lee JM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Sep 26;32(39):13587-96
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Sep 26;32(39):13587-96
CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1.
Ward AJ, Rimer M, Killian JM, Dowling JJ, Cooper TA
Human molecular genetics 2010 Sep 15;19(18):3614-22
Human molecular genetics 2010 Sep 15;19(18):3614-22
Ectopic expression of CGG containing mRNA is neurotoxic in mammals.
Hashem V, Galloway JN, Mori M, Willemsen R, Oostra BA, Paylor R, Nelson DL
Human molecular genetics 2009 Jul 1;18(13):2443-51
Human molecular genetics 2009 Jul 1;18(13):2443-51
Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy.
Orengo JP, Chambon P, Metzger D, Mosier DR, Snipes GJ, Cooper TA
Proceedings of the National Academy of Sciences of the United States of America 2008 Feb 19;105(7):2646-51
Proceedings of the National Academy of Sciences of the United States of America 2008 Feb 19;105(7):2646-51
Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice.
Kress C, Gautier-Courteille C, Osborne HB, Babinet C, Paillard L
Molecular and cellular biology 2007 Feb;27(3):1146-57
Molecular and cellular biology 2007 Feb;27(3):1146-57
Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy.
Lin X, Miller JW, Mankodi A, Kanadia RN, Yuan Y, Moxley RT, Swanson MS, Thornton CA
Human molecular genetics 2006 Jul 1;15(13):2087-97
Human molecular genetics 2006 Jul 1;15(13):2087-97
Nuclear RNA foci in the heart in myotonic dystrophy.
Mankodi A, Lin X, Blaxall BC, Swanson MS, Thornton CA
Circulation research 2005 Nov 25;97(11):1152-5
Circulation research 2005 Nov 25;97(11):1152-5
Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2.
Mankodi A, Teng-Umnuay P, Krym M, Henderson D, Swanson M, Thornton CA
Annals of neurology 2003 Dec;54(6):760-8
Annals of neurology 2003 Dec;54(6):760-8
Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy.
Savkur RS, Philips AV, Cooper TA
Nature genetics 2001 Sep;29(1):40-7
Nature genetics 2001 Sep;29(1):40-7
A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator.
Good PJ, Chen Q, Warner SJ, Herring DC
The Journal of biological chemistry 2000 Sep 15;275(37):28583-92
The Journal of biological chemistry 2000 Sep 15;275(37):28583-92
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Detection of the subcellular distribution of CUGBP1 (nuclear, non-nucleolar) in normal and DM1 (dystrophia myotonica) myoblasts using ABIN152357.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS
