Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR04009G - Provider product page
- Provider
- Leading Biology
- Product name
- SEPT5 Antibody (N-term)
- Antibody type
- Polyclonal
- Description
- This gene is a member of the septin gene family ofnucleotide binding proteins, originally described in yeast as celldivision cycle regulatory proteins. Septins are highly conserved inyeast, Drosophila, and mouse and appear to regulate cytoskeletalorganization. Disruption of septin function disturbs cytokinesisand results in large multinucleate or polyploid cells. This gene ismapped to 22q11, the region frequently deleted in DiGeorge andvelocardiofacial syndromes. A translocation involving the MLL geneand this gene has also been reported in patients with acute myeloidleukemia. Alternative splicing results in multiple transcriptvariants. The presence of a non-consensus polyA signal (AACAAT) inthis gene also results in read-through transcription into thedownstream neighboring gene (GP1BB; platelet glycoprotein Ib),whereby larger, non-coding transcripts are produced. [provided byRefSeq].
- Reactivity
- Human
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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