Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 303908 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#303908, RRID:AB_314388
- Product name
- LEAF™ Purified anti-human CD42b [HIP1]
- Antibody type
- Monoclonal
- Antigen
- CD42b
- Description
- CD42b is a 145 kD glycoprotein known as gpIbα. It is composed in a heterodimer with a β chain (CD42c, gpIbβ) through a disulfide bond. CD42b is expressed on platelets and megakaryocytes. CD42b/c heterodimer forms a complex with CD42a and d and acts as the receptor for Von Willibrand factor and thrombin.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 500 µg
- Concentration
- 1 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4 °C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
Submitted references The CX3C chemokine fractalkine mediates platelet adhesion via the von Willebrand receptor glycoprotein Ib.
Meyer dos Santos S, Klinkhardt U, Scholich K, Nelson K, Monsefi N, Deckmyn H, Kuczka K, Zorn A, Harder S
Blood 2011 May 5;117(18):4999-5008
Blood 2011 May 5;117(18):4999-5008
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human platelets stained withCD42b PE
- Conjugate
- Unconjugated