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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL8387 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-TNFRSF4 Monoclonal antibody, clone BDU46 [FITC]
- Antibody type
- Monoclonal
- Description
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Antibody clone number
- BDU46
- Vial size
- 25 tests
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