BS60920

antibody from Bioworld Technology, Inc
Targeting: CSF2RA alphaGMR, CD116, CSF2R
Provider product page for BS60920

Antibody data

Product number
BS60920 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CSF2RA polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human CSF2RA.
Description
The human IL-3, IL-5 and GM-CSF receptors are each composed of both unique a subunits and a common ÉÇ subunit. The a subunits are low affinity ligand binding proteins while the ÉÇ subunits do not themselves bind ligand, but are required for high affinity binding by the a subunits. In contrast, the mouse IL-3 receptor has two distinct ÉÇ subunits, one that functions only in IL-3 mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine ÉÇ-subunits are 91% homologous at the amino acid level but only 56% homologous to the human ÉÇ subunit. Although neither the murine nor the human ÉÇ subunit contains tyrosine kinase domains, both activate tyrosine phosphorylation mediated signaling pathways.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CSF2RA protein structure - BS60920 shown in red.