305902

antibody from BioLegend
Targeting: CSF2RA alphaGMR, CD116, CSF2R
Provider product page for 305902
Western blot
Immunoprecipitation
Immunohistochemistry
Flow cytometry

Antibody data

Product number
305902 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#305902, RRID:AB_314568
Product name
Purified anti-human CD116
Antibody type
Monoclonal
Antigen
Human GM-CSFRα transfected COS cells
Description
CD116 is a 70-85 kD α chain of the GM-CSF receptor. It combines with CDw131 β chain to form the high affinity GM-CSF receptor. A soluble form of CD116, which binds GM-CSF with a relatively low affinity, has been identified. In addition, an alternatively spliced form of CD116 with an altered cytoplasmic tail has been described. CD116 is expressed on various myeloid cells including monocytes, macrophages, neutrophils, eosinophils, dendritic cells and their precursors, fibroblasts, and endothelial cells. CD116 is expressed on myeloid leukemias, osteogenic sarcoma cell lines, osteoblast-like cells and breast and lung carcinoma cell lines.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
CSF2RA protein structure - 305902 shown in red.