RILP

This gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology. [provided by RefSeq, Sep 2011]

Description

Rab interacting lysosomal protein

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

17:p13.3 (1646145 - 1649866)

Ensembl ID

ENSG00000167705  (ver. 99.38)

Orthologs

Mouse Rilp: ENSMUSG00000038195

UniProt

Q96NA2

neXtProt

NX_Q96NA2

Human splice variants
Mouse splice variants