Tissue expression
Cell line expression
Protein structure
PSPN
PersephinPSP
This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma. [provided by RefSeq, Aug 2016]
Top validated antibodies |
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| Proteintech Group | 1 references | Polyclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| LSBio | Polyclonal |
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| Bioss | 1 references | Polyclonal |
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