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- Product number
- 18263-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18263-1-AP, RRID:AB_2163284
- Product name
- PHLDA1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PHLDA1 antibody (Cat. #18263-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references PHLDA1 is a shared diagnostic and key mediator of inflammatory fibrosis in heart and kidney.
Multiple Machine Learning Identifies Key Gene PHLDA1 Suppressing NAFLD Progression.
PHLDA1 contributes to hypoxic ischemic brain injury in neonatal rats via inhibiting FUNDC1-mediated mitophagy.
Egr1 promotes Nlrc4-dependent neuronal pyroptosis through phlda1 in an in-vitro model of intracerebral hemorrhage.
TDAG51-Deficiency Podocytes are Protected from High-Glucose-Induced Damage Through Nrf2 Activation via the AKT-GSK-3β Pathway.
Loss of PHLDA1 has a protective role in OGD/R-injured neurons via regulation of the GSK-3β/Nrf2 pathway.
PHLDA1 is a new therapeutic target of oxidative stress and ischemia reperfusion-induced myocardial injury.
PHLDA1 promotes microglia-mediated neuroinflammation via regulating K63-linked ubiquitination of TRAF6.
lncRNA HIF1A Antisense RNA 2 Modulates Trophoblast Cell Invasion and Proliferation through Upregulating PHLDA1 Expression.
The long non-coding RNA SNHG1 promotes glioma progression by competitively binding to miR-194 to regulate PHLDA1 expression.
Hua L, Shen L, Tao Y, Wang C, Shao X
Frontiers in immunology 2026;17:1765221
Frontiers in immunology 2026;17:1765221
Multiple Machine Learning Identifies Key Gene PHLDA1 Suppressing NAFLD Progression.
Yang Z, Chen Z, Wang J, Li Y, Zhang H, Xiang Y, Zhang Y, Shao Z, Wu P, Lu D, Lin H, Tong Z, Liu J, Dong Q
Inflammation 2025 Aug;48(4):1912-1928
Inflammation 2025 Aug;48(4):1912-1928
PHLDA1 contributes to hypoxic ischemic brain injury in neonatal rats via inhibiting FUNDC1-mediated mitophagy.
Jiang XL, Zhang ZB, Feng CX, Lin CJ, Yang H, Tan LL, Ding X, Xu LX, Li G, Pan T, Qin ZH, Sun B, Feng X, Li M
Acta pharmacologica Sinica 2024 Sep;45(9):1809-1820
Acta pharmacologica Sinica 2024 Sep;45(9):1809-1820
Egr1 promotes Nlrc4-dependent neuronal pyroptosis through phlda1 in an in-vitro model of intracerebral hemorrhage.
Wang J, Gu D, Jin K, Shen H, Qian Y
Neuroreport 2024 Jun 5;35(9):590-600
Neuroreport 2024 Jun 5;35(9):590-600
TDAG51-Deficiency Podocytes are Protected from High-Glucose-Induced Damage Through Nrf2 Activation via the AKT-GSK-3β Pathway.
Liu C, Li Y, Wang X
Inflammation 2022 Aug;45(4):1520-1533
Inflammation 2022 Aug;45(4):1520-1533
Loss of PHLDA1 has a protective role in OGD/R-injured neurons via regulation of the GSK-3β/Nrf2 pathway.
Yang F, Chen R
Human & experimental toxicology 2021 Nov;40(11):1909-1920
Human & experimental toxicology 2021 Nov;40(11):1909-1920
PHLDA1 is a new therapeutic target of oxidative stress and ischemia reperfusion-induced myocardial injury.
Guo Y, Jia P, Chen Y, Yu H, Xin X, Bao Y, Yang H, Wu N, Sun Y, Jia D
Life sciences 2020 Mar 15;245:117347
Life sciences 2020 Mar 15;245:117347
PHLDA1 promotes microglia-mediated neuroinflammation via regulating K63-linked ubiquitination of TRAF6.
Han C, Yan P, He T, Cheng J, Zheng W, Zheng LT, Zhen X
Brain, behavior, and immunity 2020 Aug;88:640-653
Brain, behavior, and immunity 2020 Aug;88:640-653
lncRNA HIF1A Antisense RNA 2 Modulates Trophoblast Cell Invasion and Proliferation through Upregulating PHLDA1 Expression.
Wu D, Yang N, Xu Y, Wang S, Zhang Y, Sagnelli M, Hui B, Huang Z, Sun L
Molecular therapy. Nucleic acids 2019 Jun 7;16:605-615
Molecular therapy. Nucleic acids 2019 Jun 7;16:605-615
The long non-coding RNA SNHG1 promotes glioma progression by competitively binding to miR-194 to regulate PHLDA1 expression.
Liu L, Shi Y, Shi J, Wang H, Sheng Y, Jiang Q, Chen H, Li X, Dong J
Cell death & disease 2019 Jun 12;10(6):463
Cell death & disease 2019 Jun 12;10(6):463
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PHLDA1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PHLDA1. This antibody recognizes human, mouse, rat antigen. The PHLDA1 antibody has been validated for the following applications: ELISA, WB analysis.
