MYO16

This gene encodes an unconventional myosin protein. The encoded protein has been proposed to act as a serine/threonine phosphatase-1 targeting or regulatory subunit. Studies in a rat cell line suggest that this protein may regulate cell cycle progression. A variant within this gene may be associated with susceptibility to schizophrenia and elevated expression of this gene has been observed in the frontal cortex of human schizophrenia patients. [provided by RefSeq, Mar 2017]

Description

Myosin XVI

Tissue specificity

Tissue enhanced (brain)

Subcell location

Vesicles

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

13 (108596152 - 109208005)

Ensembl ID

ENSG00000041515  (ver. 103.38)

Orthologs

Mouse Myo16: ENSMUSG00000039057

UniProt

Q9Y6X6

neXtProt

NX_Q9Y6X6

Human splice variants
Mouse splice variants

Protein structure