15553-1-AP

antibody from Proteintech Group

Targeting: KCTD5 FLJ20040

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

15553-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#15553-1-AP, RRID:AB_2132155

Product name

KCTD2/5/17 antibody

Antibody type

Polyclonal

Description

KCTD2/5/17 antibody (Cat. #15553-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer.

Pfeifer M, Brammeld JS, Price S, Pilling J, Bhavsar D, Farcas A, Bateson J, Sundarrajan A, Miragaia RJ, Guan N, Arnold S, Tariq L, Grondine M, Talbot S, Guerriero ML, O'Neill DJ, Young J, Company C, Dunn S, Thorpe H, Martin MJ, Maratea K, Barrell D, Ahdesmaki M, Mettetal JT, Functional Genomics Centre, Brownell J, McDermott U
Communications biology 2024 Apr 24;7(1):497

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Structural basis for the ubiquitination of G protein βγ subunits by KCTD5/Cullin3 E3 ligase.

Jiang W, Wang W, Kong Y, Zheng S
Science advances 2023 Jul 14;9(28):eadg8369

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Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis.

Ding P, Xu Y, Li L, Lv X, Li L, Chen J, Zhou D, Wang X, Wang Q, Zhang W, Liao T, Ji QH, Lei QY, Hu W
Cell reports 2022 May 31;39(9):110851

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Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer.

Gogleva A, Polychronopoulos D, Pfeifer M, Poroshin V, Ughetto M, Martin MJ, Thorpe H, Bornot A, Smith PD, Sidders B, Dry JR, Ahdesmäki M, McDermott U, Papa E, Bulusu KC
Nature communications 2022 Mar 29;13(1):1667

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Human Multisubunit E3 Ubiquitin Ligase Required for Heterotrimeric G-Protein β-Subunit Ubiquitination and Downstream Signaling.

Young BD, Sha J, Vashisht AA, Wohlschlegel JA
Journal of proteome research 2021 Sep 3;20(9):4318-4330

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HOXC10 Suppresses Browning to Maintain White Adipocyte Identity.

Tan HYA, Sim MFM, Tan SX, Ng Y, Gan SY, Li H, Neo SP, Gunaratne J, Xu F, Han W
Diabetes 2021 Aug;70(8):1654-1663

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Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.

Zeng H, Castillo-Cabrera J, Manser M, Lu B, Yang Z, Strande V, Begue D, Zamponi R, Qiu S, Sigoillot F, Wang Q, Lindeman A, Reece-Hoyes JS, Russ C, Bonenfant D, Jiang X, Wang Y, Cong F
eLife 2019 Nov 19;8

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Conserved properties of Drosophila Insomniac link sleep regulation and synaptic function.

Li Q, Kellner DA, Hatch HAM, Yumita T, Sanchez S, Machold RP, Frank CA, Stavropoulos N
PLoS genetics 2017 May;13(5):e1006815

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

HeLa cells were subjected to SDS PAGE followed by western blot with 15553-1-AP(KCTD5 antibody) at dilution of 1:500

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of Hela cells, using KCTD5 antibody 15553-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line