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- References [13]
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- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 15553-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15553-1-AP, RRID:AB_2132155
- Product name
- KCTD2/5/17 antibody
- Antibody type
- Polyclonal
- Description
- KCTD2/5/17 antibody (Cat. #15553-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references C21orf2 as a potential regulator of JAK2/STAT3 signaling in prostate cancer cell proliferation and apoptosis: an exploratory study.
CRISPR screens reveal YAP/TEAD axis as a mediator of drug-tolerant cells in EGFR-mutant NSCLC.
Heterozygous Kctd5 knockout mice exhibit abnormal lipid metabolism.
The G protein modifier KCTD5 tunes the decoding of neuromodulatory signals necessary for motor function in striatal neurons.
KCTD proteins regulate morphine dependence via heterologous sensitization of adenylyl cyclase 1 in mice.
Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer.
Structural basis for the ubiquitination of G protein βγ subunits by KCTD5/Cullin3 E3 ligase.
Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis.
Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer.
Human Multisubunit E3 Ubiquitin Ligase Required for Heterotrimeric G-Protein β-Subunit Ubiquitination and Downstream Signaling.
HOXC10 Suppresses Browning to Maintain White Adipocyte Identity.
Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.
Conserved properties of Drosophila Insomniac link sleep regulation and synaptic function.
Jiang S, Su S, Wang D
BMC cancer 2026 Jan 29;26(1)
BMC cancer 2026 Jan 29;26(1)
CRISPR screens reveal YAP/TEAD axis as a mediator of drug-tolerant cells in EGFR-mutant NSCLC.
Yusuf M
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb;399(4):5761-5776
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb;399(4):5761-5776
Heterozygous Kctd5 knockout mice exhibit abnormal lipid metabolism.
Ling Q, Cao M, Zhang HA, Li X, Wang W, Wang Z, Sun Q, Liang Z, Huang W, Wang M, Li X, Lin C, Jiang X, Pan JA, Peng X
The international journal of biochemistry & cell biology 2025 Nov;188:106851
The international journal of biochemistry & cell biology 2025 Nov;188:106851
The G protein modifier KCTD5 tunes the decoding of neuromodulatory signals necessary for motor function in striatal neurons.
Sloan DC, Liao Y, Ray F, Muntean BS
PLoS biology 2025 Apr;23(4):e3003117
PLoS biology 2025 Apr;23(4):e3003117
KCTD proteins regulate morphine dependence via heterologous sensitization of adenylyl cyclase 1 in mice.
Ding Z, Zhang C, Yang H, Chen J, Sun Z, Zhen X
PLoS biology 2024 Jul;22(7):e3002716
PLoS biology 2024 Jul;22(7):e3002716
Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer.
Pfeifer M, Brammeld JS, Price S, Pilling J, Bhavsar D, Farcas A, Bateson J, Sundarrajan A, Miragaia RJ, Guan N, Arnold S, Tariq L, Grondine M, Talbot S, Guerriero ML, O'Neill DJ, Young J, Company C, Dunn S, Thorpe H, Martin MJ, Maratea K, Barrell D, Ahdesmaki M, Mettetal JT, Functional Genomics Centre, Brownell J, McDermott U
Communications biology 2024 Apr 24;7(1):497
Communications biology 2024 Apr 24;7(1):497
Structural basis for the ubiquitination of G protein βγ subunits by KCTD5/Cullin3 E3 ligase.
Jiang W, Wang W, Kong Y, Zheng S
Science advances 2023 Jul 14;9(28):eadg8369
Science advances 2023 Jul 14;9(28):eadg8369
Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis.
Ding P, Xu Y, Li L, Lv X, Li L, Chen J, Zhou D, Wang X, Wang Q, Zhang W, Liao T, Ji QH, Lei QY, Hu W
Cell reports 2022 May 31;39(9):110851
Cell reports 2022 May 31;39(9):110851
Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer.
Gogleva A, Polychronopoulos D, Pfeifer M, Poroshin V, Ughetto M, Martin MJ, Thorpe H, Bornot A, Smith PD, Sidders B, Dry JR, Ahdesmäki M, McDermott U, Papa E, Bulusu KC
Nature communications 2022 Mar 29;13(1):1667
Nature communications 2022 Mar 29;13(1):1667
Human Multisubunit E3 Ubiquitin Ligase Required for Heterotrimeric G-Protein β-Subunit Ubiquitination and Downstream Signaling.
Young BD, Sha J, Vashisht AA, Wohlschlegel JA
Journal of proteome research 2021 Sep 3;20(9):4318-4330
Journal of proteome research 2021 Sep 3;20(9):4318-4330
HOXC10 Suppresses Browning to Maintain White Adipocyte Identity.
Tan HYA, Sim MFM, Tan SX, Ng Y, Gan SY, Li H, Neo SP, Gunaratne J, Xu F, Han W
Diabetes 2021 Aug;70(8):1654-1663
Diabetes 2021 Aug;70(8):1654-1663
Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.
Zeng H, Castillo-Cabrera J, Manser M, Lu B, Yang Z, Strande V, Begue D, Zamponi R, Qiu S, Sigoillot F, Wang Q, Lindeman A, Reece-Hoyes JS, Russ C, Bonenfant D, Jiang X, Wang Y, Cong F
eLife 2019 Nov 19;8
eLife 2019 Nov 19;8
Conserved properties of Drosophila Insomniac link sleep regulation and synaptic function.
Li Q, Kellner DA, Hatch HAM, Yumita T, Sanchez S, Machold RP, Frank CA, Stavropoulos N
PLoS genetics 2017 May;13(5):e1006815
PLoS genetics 2017 May;13(5):e1006815
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15553-1-AP(KCTD5 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using KCTD5 antibody 15553-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
