BS5884

antibody from Bioworld Technology, Inc
Targeting: RASSF2 CENP-34, KIAA0168
Provider product page for BS5884

Antibody data

Product number
BS5884 - Provider product page
Provider
Bioworld Technology, Inc
Product name
RASSF2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 152-197 of Human RASSF2.
Description
Ras is a small GTP-binding protein involved in many cellular processes, including proliferation, differentiation and apoptosis. Ras transmits signals of cell surface receptors by binding to a variety of effector molecules. In addition to the well-characterized effectors Raf and PI-3 kinase, Ras also interacts with a group of homologous, noncatalytic proteins composed of RASSF1, RASSF2, RASSF3, AD037 and Nore1. RASSF1 is a potential tumor suppressor gene that plays an important role in tumor pathogenesis. Nore1 binds to Ras in response to EGF or serum stimulation, but its function has yet to be determined. RASSF2 is a nuclear protein containing a Ras-associating domain and a SARAH domain. RASSF2 isoform A is inactivated in colorectal cancer cells by CpG island promoter hypermethylation.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
RASSF2 protein structure - BS5884 shown in red.