BS60349

CXCR1 antibody from Bioworld Technology, Inc
CD181, CDw128a, CKR-1, CMKAR1, IL8RA

Antibody data

Product number
BS60349
Provider
Bioworld Technology, Inc
Product name
CXCR1 polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS60349
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human CXCR1
Description
IL-8 has been shown to function as a potent neutrophil chemostatic and activating peptide and is an important mediator of inflammatory diseases. Two distinct human IL-8 receptors, designated IL-8RA and IL-8RB have been characterized. Both are expressed at a high level on neutrophils and to a lesser extent on monocytes and myeloid cell lines. In addition, the IL-8RA subunit is expressed in T cells such as the Jurkat cell line. Both IL-8Rs are members of the seven-transmembrane domain rhodopsin superfamily of receptors and as such, couple G proteins for signal transduction. The two receptors share 77% amino acid identity. IL-8RA exhibits high-affinity binding for IL-8 and low-affinity MGSA binding, whereas IL-8RB has high-affinity binding for both IL-8 and MGSA.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -