Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB330P-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CXCR1/IL-8RA PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human CXCR1/IL-8 RA transfectants but not the parental cell line. It does not cross-react with human CXCR2.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
AAA59159
- Isotype
- IgG
- Antibody clone number
- 42705
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Disrupting Inflammation-Associated CXCL8-CXCR1 Signaling Inhibits Tumorigenicity Initiated by Sporadic- and Colitis-Colon Cancer Stem Cells.
Human trophectoderm apposition is regulated by interferon γ-induced protein 10 (IP-10) during early implantation.
Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10.
Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis.
Severe congenital neutropenia resulting from G6PC3 deficiency with increased neutrophil CXCR4 expression and myelokathexis.
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
Duffy antigen modifies the chemokine response in human endotoxemia.
Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling.
Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2.
Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
Fisher RC, Bellamkonda K, Alex Molina L, Xiang S, Liska D, Sarvestani SK, Chakrabarti S, Berg A, Jorgensen ML, Hatala D, Chen S, Aiello A, Appelman HD, Scott EW, Huang EH
Neoplasia (New York, N.Y.) 2019 Mar;21(3):269-281
Neoplasia (New York, N.Y.) 2019 Mar;21(3):269-281
Human trophectoderm apposition is regulated by interferon γ-induced protein 10 (IP-10) during early implantation.
Sela HY, Goldman-Wohl DS, Haimov-Kochman R, Greenfield C, Natanson-Yaron S, Hamani Y, Revel A, Lavy Y, Singer O, Yachimovich-Cohen N, Turetsky T, Mandelboim O, Reubinoff B, Yagel S
Placenta 2013 Mar;34(3):222-30
Placenta 2013 Mar;34(3):222-30
Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
Cerdeira AS, Rajakumar A, Royle CM, Lo A, Husain Z, Thadhani RI, Sukhatme VP, Karumanchi SA, Kopcow HD
Journal of immunology (Baltimore, Md. : 1950) 2013 Apr 15;190(8):3939-48
Journal of immunology (Baltimore, Md. : 1950) 2013 Apr 15;190(8):3939-48
Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10.
Vujanovic L, Ballard W, Thorne SH, Vujanovic NL, Butterfield LH
Oncoimmunology 2012 Jul 1;1(4):448-457
Oncoimmunology 2012 Jul 1;1(4):448-457
Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis.
Laarman AJ, Mijnheer G, Mootz JM, van Rooijen WJ, Ruyken M, Malone CL, Heezius EC, Ward R, Milligan G, van Strijp JA, de Haas CJ, Horswill AR, van Kessel KP, Rooijakkers SH
The EMBO journal 2012 Aug 29;31(17):3607-19
The EMBO journal 2012 Aug 29;31(17):3607-19
Severe congenital neutropenia resulting from G6PC3 deficiency with increased neutrophil CXCR4 expression and myelokathexis.
McDermott DH, De Ravin SS, Jun HS, Liu Q, Priel DA, Noel P, Takemoto CM, Ojode T, Paul SM, Dunsmore KP, Hilligoss D, Marquesen M, Ulrick J, Kuhns DB, Chou JY, Malech HL, Murphy PM
Blood 2010 Oct 14;116(15):2793-802
Blood 2010 Oct 14;116(15):2793-802
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2886-98
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2886-98
CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
Carbone T, Nasorri F, Pennino D, Eyerich K, Foerster S, Cifaldi L, Traidl-Hoffman C, Behrendt H, Cavani A
Journal of immunology (Baltimore, Md. : 1950) 2010 Jan 15;184(2):1102-10
Journal of immunology (Baltimore, Md. : 1950) 2010 Jan 15;184(2):1102-10
Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
Ahern D, Lloyd CM, Robinson DS
Allergy 2009 Aug;64(8):1121-9
Allergy 2009 Aug;64(8):1121-9
Duffy antigen modifies the chemokine response in human endotoxemia.
Mayr FB, Spiel AO, Leitner JM, Firbas C, Kliegel T, Jilma-Stohlawetz P, Derendorf H, Jilma B
Critical care medicine 2008 Jan;36(1):159-65
Critical care medicine 2008 Jan;36(1):159-65
Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA
Journal of neuroimmunology 2008 Aug 13;199(1-2):35-45
Journal of neuroimmunology 2008 Aug 13;199(1-2):35-45
Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling.
Bestebroer J, Poppelier MJ, Ulfman LH, Lenting PJ, Denis CV, van Kessel KP, van Strijp JA, de Haas CJ
Blood 2007 Apr 1;109(7):2936-43
Blood 2007 Apr 1;109(7):2936-43
Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2.
Traves SL, Smith SJ, Barnes PJ, Donnelly LE
Journal of leukocyte biology 2004 Aug;76(2):441-50
Journal of leukocyte biology 2004 Aug;76(2):441-50
Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
Liu LY, Jarjour NN, Busse WW, Kelly EA
The Journal of allergy and clinical immunology 2003 Sep;112(3):556-62
The Journal of allergy and clinical immunology 2003 Sep;112(3):556-62
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CXCR1/IL-8 RA in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR1/IL-8 RA PE-conjugated Monoclonal Antibody (Catalog # FAB330P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.