320612

antibody from BioLegend
Targeting: CXCR1 CD181, CDw128a, CKR-1, CMKAR1, IL8RA
Provider product page for 320612

Antibody data

Product number
320612 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#320612, RRID:AB_2126475
Product name
APC anti-human CD181 (CXCR1)
Antibody type
Monoclonal
Antigen
Human CXCR1 transfected L1.2 cells
Description
CXCR1 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor A (IL-8RA), CD181, and CDw128a. It is a CXC chemokine receptor belongs to G protein-coupled receptor (CPCR) family. CXCR1 is expressed as homodimer or heterodimer with CXCR2 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. The expression level of CXCR1 on monocytes is lower that of CXCR2. CXCR1 mediates nurophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO-α(CXCL1).
Reactivity
Human
Host
Mouse
Conjugate
Red dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
CXCR1 protein structure - 320612 shown in red.