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Western blot
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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- HPA039975 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA039975, RRID:AB_10793858
- Product name
- Anti-MNS1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human MNS1, Gene description: meiosis-specific nuclear structural 1, Alternative Gene Names: FLJ11222, SPATA40, Validated applications: WB, ICC, IHC, Uniprot ID: Q8NEH6, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Biallelic Variants in MNS1 Are Associated with Laterality Defects and Respiratory Involvement
Sperm flagellar 2 (SPEF2) is essential for sperm flagellar assembly in humans
A novel homozygous frameshift mutation in MNS1 associated with severe oligoasthenoteratozoospermia in humans
Homozygous loss-of-function mutations in MNS1 cause laterality defects and likely male infertility
Hjeij R, Leslie J, Rizk H, Dworniczak B, Olbrich H, Raidt J, Bode S, Gardham A, Stals K, Al-Haggar M, Osman E, Crosby A, Eldesoky T, Baple E, Omran H
Cells 2024;13(12):1017
Cells 2024;13(12):1017
Sperm flagellar 2 (SPEF2) is essential for sperm flagellar assembly in humans
Li D, Yang X, Tu C, Wang W, Meng L, Lu G, Tan Y, Zhang Q, Du J
Asian Journal of Andrology 2022;24(4):359-366
Asian Journal of Andrology 2022;24(4):359-366
A novel homozygous frameshift mutation in MNS1 associated with severe oligoasthenoteratozoospermia in humans
Li Y, Wang W, Tu C, Meng L, Hu T, Du J, Lin G, Nie H, Tan Y
Asian Journal of Andrology 2021;23(2):197-204
Asian Journal of Andrology 2021;23(2):197-204
Homozygous loss-of-function mutations in MNS1 cause laterality defects and likely male infertility
O’Bryan M, Ta-Shma A, Hjeij R, Perles Z, Dougherty G, Abu Zahira I, Letteboer S, Antony D, Darwish A, Mans D, Spittler S, Edelbusch C, Cindrić S, Nöthe-Menchen T, Olbrich H, Stuhlmann F, Aprea I, Pennekamp P, Loges N, Breuer O, Shaag A, Rein A, Gulec E, Gezdirici A, Abitbul R, Elias N, Amirav I, Schmidts M, Roepman R, Elpeleg O, Omran H
PLOS Genetics 2018;14(8):e1007602
PLOS Genetics 2018;14(8):e1007602
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Recombinant expression validation
- Main image
- Experimental details
- Western blot analysis in control (vector only transfected HEK293T lysate) and MNS1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY413117).
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
- Sample type
- Human
