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- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 18354-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- HNRNPL antibody
- Antibody type
- Polyclonal
- Description
- HNRNPL antibody (Cat. #18354-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Transcriptional readthrough precedes alternative splicing programs triggered in CML cells by imatinib.
hnRNPL phase separation activates PIK3CB transcription and promotes glycolysis in ovarian cancer.
SENP3 protects hepatocyte from pyroptosis during acute liver injury through deSUMOylation of HNRNPL.
Context-dependent Interactors Regulate TDP-43 Dysfunction in ALS/FTLD.
PAIP1 binds to pre-mRNA and regulates alternative splicing of cancer pathway genes including VEGFA.
CFIm25 regulates human stem cell function independently of its role in mRNA alternative polyadenylation.
HNRNPL Is Identified and Validated as a Prognostic Biomarker Associated with Microsatellite Instability in Human Gastric Cancer.
Heterogeneous Nuclear Ribonucleoprotein L Negatively Regulates Foot-and-Mouth Disease Virus Replication through Inhibition of Viral RNA Synthesis by Interacting with the Internal Ribosome Entry Site in the 5' Untranslated Region.
Fast and unbiased purification of RNA-protein complexes after UV cross-linking.
Genome-wide CRISPR screen identifies ELP5 as a determinant of gemcitabine sensitivity in gallbladder cancer.
C1QBP negatively regulates the activation of oncoprotein YBX1 in the renal cell carcinoma as revealed by interactomics analysis.
Podszywałow-Bartnicka P, Shine M, Lin J, Neugebauer KM
Science advances 2026 Mar 20;12(12):eaea2475
Science advances 2026 Mar 20;12(12):eaea2475
hnRNPL phase separation activates PIK3CB transcription and promotes glycolysis in ovarian cancer.
Qin F, Wang Y, Yang C, Ren Y, Wei Q, Tang Y, Xu J, Wang H, Luo F, Luo Q, Luo X, Liu X, Yang D, Zuo X, Yang Y, Cheng C, Xu J, Wang W, Liu T, Yi P
Nature communications 2025 May 24;16(1):4828
Nature communications 2025 May 24;16(1):4828
SENP3 protects hepatocyte from pyroptosis during acute liver injury through deSUMOylation of HNRNPL.
Xiong X, Zhi Y, Yang N, Zhao W, Wang S, Zhu H, Tang J, Yi J, Sun X, Yang J
iScience 2025 Aug 15;28(8):113067
iScience 2025 Aug 15;28(8):113067
Context-dependent Interactors Regulate TDP-43 Dysfunction in ALS/FTLD.
Xie L, Zhu Y, Hurtle BT, Wright M, Robinson JL, Mauna JC, Brown EE, Ngo M, Bergmann CA, Xu J, Merjane J, Gleixner AM, Grigorean G, Liu F, Rossoll W, Lee EB, Kiskinis E, Chikina M, Donnelly CJ
bioRxiv : the preprint server for biology 2025 Apr 9;
bioRxiv : the preprint server for biology 2025 Apr 9;
PAIP1 binds to pre-mRNA and regulates alternative splicing of cancer pathway genes including VEGFA.
Zheng J, Zhang X, Xue Y, Shao W, Wei Y, Mi S, Yang X, Hu L, Zhang Y, Liang M
BMC genomics 2024 Oct 3;25(1):926
BMC genomics 2024 Oct 3;25(1):926
CFIm25 regulates human stem cell function independently of its role in mRNA alternative polyadenylation.
Ran Y, Huang S, Shi J, Feng Q, Deng Y, Xiang AP, Yao C
RNA biology 2022;19(1):686-702
RNA biology 2022;19(1):686-702
HNRNPL Is Identified and Validated as a Prognostic Biomarker Associated with Microsatellite Instability in Human Gastric Cancer.
Yu X, Cao F, Yu Y, Li Y, Zhang J, Xu T, Di Q, Wu G, Zhang Z, Wang R, Li Y
DNA and cell biology 2021 Oct;40(10):1251-1260
DNA and cell biology 2021 Oct;40(10):1251-1260
Heterogeneous Nuclear Ribonucleoprotein L Negatively Regulates Foot-and-Mouth Disease Virus Replication through Inhibition of Viral RNA Synthesis by Interacting with the Internal Ribosome Entry Site in the 5' Untranslated Region.
Sun C, Liu M, Chang J, Yang D, Zhao B, Wang H, Zhou G, Weng C, Yu L
Journal of virology 2020 May 4;94(10)
Journal of virology 2020 May 4;94(10)
Fast and unbiased purification of RNA-protein complexes after UV cross-linking.
Urdaneta EC, Beckmann BM
Methods (San Diego, Calif.) 2020 Jun 1;178:72-82
Methods (San Diego, Calif.) 2020 Jun 1;178:72-82
Genome-wide CRISPR screen identifies ELP5 as a determinant of gemcitabine sensitivity in gallbladder cancer.
Xu S, Zhan M, Jiang C, He M, Yang L, Shen H, Huang S, Huang X, Lin R, Shi Y, Liu Q, Chen W, Mohan M, Wang J
Nature communications 2019 Dec 2;10(1):5492
Nature communications 2019 Dec 2;10(1):5492
C1QBP negatively regulates the activation of oncoprotein YBX1 in the renal cell carcinoma as revealed by interactomics analysis.
Wang Y, Yue D, Xiao M, Qi C, Chen Y, Sun D, Zhang N, Chen R
Journal of proteome research 2015 Feb 6;14(2):804-13
Journal of proteome research 2015 Feb 6;14(2):804-13
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 18354-1-AP( HNRNPL Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HNRNPL antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human HNRNPL. This antibody recognizes human,mouse,rat antigen. The HNRNPL antibody has been validated for the following applications: ELISA, WB, IF, IHC analysis.
