Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10328-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10328-1-AP, RRID:AB_2236500
- Product name
- NXF1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NXF1 antibody (Cat. #10328-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TRAF2 mediates Wnt-induced β-catenin nuclear translocation by associating with the nuclear pore complex.
NXF1 suppresses progression of endometrial cancer by interacting with the SRSF3 to regulate SP4 splicing.
Interaction of CDK12 with NXF1 is a new node for the linking mechanism between transcription and transportation of mRNA.
TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT.
SUN5, a testis-specific nuclear membrane protein, participates in recruitment and export of nuclear mRNA in spermatogenesis.
Data of RNA-seq transcriptomes of liver, bone, heart, kidney and blood in klotho mice at a pre-symptomatic state and the effect of a traditional Japanese multi-herbal medicine, juzentaihoto.
Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells.
Intron retention as a new pre-symptomatic marker of aging and its recovery to the normal state by a traditional Japanese multi-herbal medicine.
The mRNA Export Receptor NXF1 Coordinates Transcriptional Dynamics, Alternative Polyadenylation, and mRNA Export.
Intronless mRNAs transit through nuclear speckles to gain export competence.
Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy.
Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.
Fragile X mental retardation protein FMRP binds mRNAs in the nucleus.
XIST RNA exhibits nuclear retention and exhibits reduced association with the export factor TAP/NXF1.
Yang M, Xuan Y, Hao P, Li Y, Zhang C, Zhao W, Zhang Y, Zhang X, Zhou X, Zhu H, Li H, Yang Y, Wang J, Yan R, Qu Y, Ke X
Life sciences 2025 Sep 15;377:123722
Life sciences 2025 Sep 15;377:123722
NXF1 suppresses progression of endometrial cancer by interacting with the SRSF3 to regulate SP4 splicing.
Meng N, Li L, Yang X, Tang H, Wang J, Zhang S, Xia Z, Yao J, Zhang Q, Hu C, Su C, Duan R
iScience 2025 Aug 15;28(8):113113
iScience 2025 Aug 15;28(8):113113
Interaction of CDK12 with NXF1 is a new node for the linking mechanism between transcription and transportation of mRNA.
Ebara S, Yoshida M, Yamakawa H, Shimokawa K, Inoue Y, Tauchi H, Morishita D
Biochemical and biophysical research communications 2024 Nov 26;735:150608
Biochemical and biophysical research communications 2024 Nov 26;735:150608
TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT.
Sun H, Li X, Long Q, Wang X, Zhu W, Chen E, Zhou W, Yang H, Huang C, Deng W, Chen M
iScience 2024 Jun 21;27(6):109869
iScience 2024 Jun 21;27(6):109869
SUN5, a testis-specific nuclear membrane protein, participates in recruitment and export of nuclear mRNA in spermatogenesis.
He X, Zhang Y, Mao Z, Liu G, Huang L, Liu X, Su Y, Xing X
Acta biochimica et biophysica Sinica 2024 Aug 6;56(11):1673-1686
Acta biochimica et biophysica Sinica 2024 Aug 6;56(11):1673-1686
Data of RNA-seq transcriptomes of liver, bone, heart, kidney and blood in klotho mice at a pre-symptomatic state and the effect of a traditional Japanese multi-herbal medicine, juzentaihoto.
Okada N, Oshima K, Iwasaki Y, Maruko A, Matsumura K, Iioka E, Vu TD, Fujitsuka N, Nishi A, Sugiyama A, Nishiyama M, Kaneko A, Mizoguchi K, Yamamoto M, Nishimura S
Data in brief 2022 Jun;42:108197
Data in brief 2022 Jun;42:108197
Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells.
Chen M, Long Q, Borrie MS, Sun H, Zhang C, Yang H, Shi D, Gartenberg MR, Deng W
PLoS genetics 2021 Nov;17(11):e1009899
PLoS genetics 2021 Nov;17(11):e1009899
Intron retention as a new pre-symptomatic marker of aging and its recovery to the normal state by a traditional Japanese multi-herbal medicine.
Okada N, Oshima K, Iwasaki Y, Maruko A, Matsumura K, Iioka E, Vu TD, Fujitsuka N, Nishi A, Sugiyama A, Nishiyama M, Kaneko A, Mizoguchi K, Yamamoto M, Nishimura S
Gene 2021 Aug 20;794:145752
Gene 2021 Aug 20;794:145752
The mRNA Export Receptor NXF1 Coordinates Transcriptional Dynamics, Alternative Polyadenylation, and mRNA Export.
Chen S, Wang R, Zheng D, Zhang H, Chang X, Wang K, Li W, Fan J, Tian B, Cheng H
Molecular cell 2019 Apr 4;74(1):118-131.e7
Molecular cell 2019 Apr 4;74(1):118-131.e7
Intronless mRNAs transit through nuclear speckles to gain export competence.
Wang K, Wang L, Wang J, Chen S, Shi M, Cheng H
The Journal of cell biology 2018 Nov 5;217(11):3912-3929
The Journal of cell biology 2018 Nov 5;217(11):3912-3929
Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy.
Stubbs SH, Conrad NK
Nucleic acids research 2015 Jan;43(1):504-19
Nucleic acids research 2015 Jan;43(1):504-19
Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.
Zhang L, Das P, Schmolke M, Manicassamy B, Wang Y, Deng X, Cai L, Tu BP, Forst CV, Roth MG, Levy DE, García-Sastre A, de Brabander J, Phillips MA, Fontoura BM
The Journal of cell biology 2012 Feb 6;196(3):315-26
The Journal of cell biology 2012 Feb 6;196(3):315-26
Fragile X mental retardation protein FMRP binds mRNAs in the nucleus.
Kim M, Bellini M, Ceman S
Molecular and cellular biology 2009 Jan;29(1):214-28
Molecular and cellular biology 2009 Jan;29(1):214-28
XIST RNA exhibits nuclear retention and exhibits reduced association with the export factor TAP/NXF1.
Cohen HR, Panning B
Chromosoma 2007 Aug;116(4):373-83
Chromosoma 2007 Aug;116(4):373-83
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The NXF1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NXF1. This antibody recognizes human, mouse, rat antigen. The NXF1 antibody has been validated for the following applications: ELISA, WB analysis.