UTRN

gene product
DMDL, DRP, DRP1
This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
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Antibodies

 

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Antibodypedia Validation Initiative

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  or   Clear
Enhanced validation
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50 antibodies from 15 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
2 antibodies
LifeSpan BioSciences, Inc.
12 antibodies
antibodies-online
5 antibodies
Abnova Corporation
2 antibodies
Atlas Antibodies
1 antibody
Invitrogen Antibodies
1 antibody
Santa Cruz Biotechnology
1 antibody
Biorbyt
5 antibodies
MyBioSource
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Diagnostics
2 antibodies
Sigma-Aldrich
2 antibodies
United States Biological
1 antibody
St John's Laboratory
1 antibody