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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- HPA042420 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA042420, RRID:AB_2677990
- Product name
- Anti-COL7A1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human COL7A1, Gene description: collagen, type VII, alpha 1, Alternative Gene Names: EBD1, EBDCT, EBR1, Validated applications: IHC, Uniprot ID: Q02388, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references The potential role of collagen type VII in breast cancer proliferation
Identification of novel small molecule-based strategies of COL7A1 upregulation and readthrough activity for the treatment of recessive dystrophic epidermolysis bullosa
In vivo topical gene therapy for recessive dystrophic epidermolysis bullosa: a phase 1 and 2 trial
Collagen VII maintains proteostasis in dermal fibroblasts by scaffolding TANGO1 cargo
Pérez-Díaz S, Lindberg J, Anerillas L, Kingham P, Sund M, Rask G, Svensson J, Jansson M, Wiberg R
Cancer Cell International 2024;24(1)
Cancer Cell International 2024;24(1)
Identification of novel small molecule-based strategies of COL7A1 upregulation and readthrough activity for the treatment of recessive dystrophic epidermolysis bullosa
Jover I, Ramos M, Escámez M, Lozoya E, Tormo J, de Prado-Verdún D, Mencía Á, Pont M, Puig C, Larraufie M, Gutiérrez-Caballero C, Reyes F, Trincado J, García-González V, Cerrato R, Andrés M, Crespo M, Vicente F, Godessart N, Genilloud O, Larcher F, Nueda A
Scientific Reports 2024;14(1)
Scientific Reports 2024;14(1)
In vivo topical gene therapy for recessive dystrophic epidermolysis bullosa: a phase 1 and 2 trial
Gurevich I, Agarwal P, Zhang P, Dolorito J, Oliver S, Liu H, Reitze N, Sarma N, Bagci I, Sridhar K, Kakarla V, Yenamandra V, O’Malley M, Prisco M, Tufa S, Keene D, South A, Krishnan S, Marinkovich M
Nature Medicine 2022;28(4):780-788
Nature Medicine 2022;28(4):780-788
Collagen VII maintains proteostasis in dermal fibroblasts by scaffolding TANGO1 cargo
Cao Q, Tartaglia G, Alexander M, Park P, Poojan S, Farshchian M, Fuentes I, Chen M, McGrath J, Palisson F, Salas-Alanis J, South A
Matrix Biology 2022;111
Matrix Biology 2022;111
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human skin and liver tissues using HPA042420 antibody. Corresponding COL7A1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
