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Immunoprecipitation
Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Blocking/Neutralizing [1]
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- Product number
- MAB9311 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal BACE-1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human and mouse BACE-1 Ectodomain in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) BACE-2, recombinant mouse BACE-2, rhADAM8, rhADAM9, rhADAM10, rhADAM15, or rhTACE is observed.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references A reversible form of lysine acetylation in the ER and Golgi lumen controls the molecular stabilization of BACE1.
Costantini C, Ko MH, Jonas MC, Puglielli L
The Biochemical journal 2007 Nov 1;407(3):383-95
The Biochemical journal 2007 Nov 1;407(3):383-95
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Neutralization of BACE-1 Activity by Human/Mouse BACE-1 Antibody. Neutralization of BACE-1 Activity by Human/Mouse BACE-1 Antibody.
