Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- PAB9771 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB9771, RRID:AB_1673476
- Product name
- BACE1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of BACE1.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Identification of a novel aspartic protease (Asp 2) as beta-secretase.
Purification and cloning of amyloid precursor protein beta-secretase from human brain.
Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA, Denis P, Teplow DB, Ross S, Amarante P, Loeloff R, Luo Y, Fisher S, Fuller J, Edenson S, Lile J, Jarosinski MA, Biere AL, Curran E, Burgess T, Louis JC, Collins F, Treanor J, Rogers G, Citron M
Science (New York, N.Y.) 1999 Oct 22;286(5440):735-41
Science (New York, N.Y.) 1999 Oct 22;286(5440):735-41
Identification of a novel aspartic protease (Asp 2) as beta-secretase.
Hussain I, Powell D, Howlett DR, Tew DG, Meek TD, Chapman C, Gloger IS, Murphy KE, Southan CD, Ryan DM, Smith TS, Simmons DL, Walsh FS, Dingwall C, Christie G
Molecular and cellular neurosciences 1999 Dec;14(6):419-27
Molecular and cellular neurosciences 1999 Dec;14(6):419-27
Purification and cloning of amyloid precursor protein beta-secretase from human brain.
Sinha S, Anderson JP, Barbour R, Basi GS, Caccavello R, Davis D, Doan M, Dovey HF, Frigon N, Hong J, Jacobson-Croak K, Jewett N, Keim P, Knops J, Lieberburg I, Power M, Tan H, Tatsuno G, Tung J, Schenk D, Seubert P, Suomensaari SM, Wang S, Walker D, Zhao J, McConlogue L, John V
Nature 1999 Dec 2;402(6761):537-40
Nature 1999 Dec 2;402(6761):537-40
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of BACE1 expression in human brain tissue (lane 1) and in NIH/3T3 (lane 2) with BACE1 polyclonal antibody.