Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PAB9981 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB9981, RRID:AB_1672415
- Product name
- BACE1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to C-terminus of human BACE1.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Vial size
- 100 μg
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Identification of a novel aspartic protease (Asp 2) as beta-secretase.
Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.
Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA, Denis P, Teplow DB, Ross S, Amarante P, Loeloff R, Luo Y, Fisher S, Fuller J, Edenson S, Lile J, Jarosinski MA, Biere AL, Curran E, Burgess T, Louis JC, Collins F, Treanor J, Rogers G, Citron M
Science (New York, N.Y.) 1999 Oct 22;286(5440):735-41
Science (New York, N.Y.) 1999 Oct 22;286(5440):735-41
Identification of a novel aspartic protease (Asp 2) as beta-secretase.
Hussain I, Powell D, Howlett DR, Tew DG, Meek TD, Chapman C, Gloger IS, Murphy KE, Southan CD, Ryan DM, Smith TS, Simmons DL, Walsh FS, Dingwall C, Christie G
Molecular and cellular neurosciences 1999 Dec;14(6):419-27
Molecular and cellular neurosciences 1999 Dec;14(6):419-27
Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.
Yan R, Bienkowski MJ, Shuck ME, Miao H, Tory MC, Pauley AM, Brashier JR, Stratman NC, Mathews WR, Buhl AE, Carter DB, Tomasselli AG, Parodi LA, Heinrikson RL, Gurney ME
Nature 1999 Dec 2;402(6761):533-7
Nature 1999 Dec 2;402(6761):533-7
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of BACE1 in human brain tissue lysate in the absence (A) or presence (B) of blocking peptide, and in mouse 3T3 cell lysate (C) with BACE1 polyclonal antibody (Cat # PAB9981) at 1 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunocytochemistry of BACE1 in NIH/3T3 cells with BACE1 polyclonal antibody (Cat # PAB9981) at 10 ug/mL .
- Validation comment
- Immunocytochemistry
