ABIN264995

antibody from antibodies-online

Targeting: BACE1 BACE

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN264995

Provider

antibodies-online

Product name

anti-beta-Site APP-Cleaving Enzyme 1 (BACE) (AA 485-501) antibody

Antibody type

Polyclonal

Description

Purified

Reactivity

Human, Mouse

Host

Rabbit

Epitope

AA 485-501

Isotype

IgG

Vial size

0.1 mg

Storage

The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.

Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA, Denis P, Teplow DB, Ross S, Amarante P, Loeloff R, Luo Y, Fisher S, Fuller J, Edenson S, Lile J, Jarosinski MA, Biere AL, Curran E, Burgess T, Louis JC, Collins F, Treanor J, Rogers G, Citron M
Science (New York, N.Y.) 1999 Oct 22;286(5440):735-41

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Identification of a novel aspartic protease (Asp 2) as beta-secretase.

Hussain I, Powell D, Howlett DR, Tew DG, Meek TD, Chapman C, Gloger IS, Murphy KE, Southan CD, Ryan DM, Smith TS, Simmons DL, Walsh FS, Dingwall C, Christie G
Molecular and cellular neurosciences 1999 Dec;14(6):419-27

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Purification and cloning of amyloid precursor protein beta-secretase from human brain.

Sinha S, Anderson JP, Barbour R, Basi GS, Caccavello R, Davis D, Doan M, Dovey HF, Frigon N, Hong J, Jacobson-Croak K, Jewett N, Keim P, Knops J, Lieberburg I, Power M, Tan H, Tatsuno G, Tung J, Schenk D, Seubert P, Suomensaari SM, Wang S, Walker D, Zhao J, McConlogue L, John V
Nature 1999 Dec 2;402(6761):537-40

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Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.

Yan R, Bienkowski MJ, Shuck ME, Miao H, Tory MC, Pauley AM, Brashier JR, Stratman NC, Mathews WR, Buhl AE, Carter DB, Tomasselli AG, Parodi LA, Heinrikson RL, Gurney ME
Nature 1999 Dec 2;402(6761):533-7