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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN499393 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-beta-Site APP-Cleaving Enzyme 1 (BACE) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Human BACE (C-Terminus) Peptide (ABIN499392)
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.
Submitted references Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Identification of a novel aspartic protease (Asp 2) as beta-secretase.
Purification and cloning of amyloid precursor protein beta-secretase from human brain.
Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.
Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA, Denis P, Teplow DB, Ross S, Amarante P, Loeloff R, Luo Y, Fisher S, Fuller J, Edenson S, Lile J, Jarosinski MA, Biere AL, Curran E, Burgess T, Louis JC, Collins F, Treanor J, Rogers G, Citron M
Science (New York, N.Y.) 1999 Oct 22;286(5440):735-41
Science (New York, N.Y.) 1999 Oct 22;286(5440):735-41
Identification of a novel aspartic protease (Asp 2) as beta-secretase.
Hussain I, Powell D, Howlett DR, Tew DG, Meek TD, Chapman C, Gloger IS, Murphy KE, Southan CD, Ryan DM, Smith TS, Simmons DL, Walsh FS, Dingwall C, Christie G
Molecular and cellular neurosciences 1999 Dec;14(6):419-27
Molecular and cellular neurosciences 1999 Dec;14(6):419-27
Purification and cloning of amyloid precursor protein beta-secretase from human brain.
Sinha S, Anderson JP, Barbour R, Basi GS, Caccavello R, Davis D, Doan M, Dovey HF, Frigon N, Hong J, Jacobson-Croak K, Jewett N, Keim P, Knops J, Lieberburg I, Power M, Tan H, Tatsuno G, Tung J, Schenk D, Seubert P, Suomensaari SM, Wang S, Walker D, Zhao J, McConlogue L, John V
Nature 1999 Dec 2;402(6761):537-40
Nature 1999 Dec 2;402(6761):537-40
Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.
Yan R, Bienkowski MJ, Shuck ME, Miao H, Tory MC, Pauley AM, Brashier JR, Stratman NC, Mathews WR, Buhl AE, Carter DB, Tomasselli AG, Parodi LA, Heinrikson RL, Gurney ME
Nature 1999 Dec 2;402(6761):533-7
Nature 1999 Dec 2;402(6761):533-7
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of BACE in human brain tissue lysate in the absence (A) or presence (B) of blocking peptide and in mouse 3T3 cell lysate (C) with AP30111PU-N BACE antibody at 1 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of BACE in 3T3 cells with AP30111PU-N BACE antibody at 10 ?g/ml.
