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LearnABIN152320
antibody from antibodies-online
Targeting: CDC73
C1orf28, FIHP, HRPT1, HRPT2, parafibromin
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- Antibody Data
- Antigen structure
- References [10]
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- Western blot [2]
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- Product number
- ABIN152320 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cell Division Cycle 73, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) (CDC73) (AA 250-300) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 250-300
- Vial size
- 100 μL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references Histone H3R17me2a mark recruits human RNA polymerase-associated factor 1 complex to activate transcription.
The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'-end processing of animal histone mRNAs.
The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression.
The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.
The parafibromin tumor suppressor protein inhibits cell proliferation by repression of the c-myc proto-oncogene.
Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice.
Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.
Parafibromin immunoreactivity: its use as an additional diagnostic marker for parathyroid tumor classification.
Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo.
The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II.
Wu J, Xu W
Proceedings of the National Academy of Sciences of the United States of America 2012 Apr 10;109(15):5675-80
Proceedings of the National Academy of Sciences of the United States of America 2012 Apr 10;109(15):5675-80
The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'-end processing of animal histone mRNAs.
Ruepp MD, Vivarelli S, Pillai RS, Kleinschmidt N, Azzouz TN, Barabino SM, Schümperli D
Nucleic acids research 2010 Nov;38(21):7637-50
Nucleic acids research 2010 Nov;38(21):7637-50
The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression.
Yang YJ, Han JW, Youn HD, Cho EJ
Nucleic acids research 2010 Jan;38(2):382-90
Nucleic acids research 2010 Jan;38(2):382-90
The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.
Rozenblatt-Rosen O, Nagaike T, Francis JM, Kaneko S, Glatt KA, Hughes CM, LaFramboise T, Manley JL, Meyerson M
Proceedings of the National Academy of Sciences of the United States of America 2009 Jan 20;106(3):755-60
Proceedings of the National Academy of Sciences of the United States of America 2009 Jan 20;106(3):755-60
The parafibromin tumor suppressor protein inhibits cell proliferation by repression of the c-myc proto-oncogene.
Lin L, Zhang JH, Panicker LM, Simonds WF
Proceedings of the National Academy of Sciences of the United States of America 2008 Nov 11;105(45):17420-5
Proceedings of the National Academy of Sciences of the United States of America 2008 Nov 11;105(45):17420-5
Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice.
Wang P, Bowl MR, Bender S, Peng J, Farber L, Chen J, Ali A, Zhang Z, Alberts AS, Thakker RV, Shilatifard A, Williams BO, Teh BT
Molecular and cellular biology 2008 May;28(9):2930-40
Molecular and cellular biology 2008 May;28(9):2930-40
Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.
Tran H, Hamada F, Schwarz-Romond T, Bienz M
Genes & development 2008 Feb 15;22(4):528-42
Genes & development 2008 Feb 15;22(4):528-42
Parafibromin immunoreactivity: its use as an additional diagnostic marker for parathyroid tumor classification.
Juhlin CC, Villablanca A, Sandelin K, Haglund F, Nordenström J, Forsberg L, Bränström R, Obara T, Arnold A, Larsson C, Höög A
Endocrine-related cancer 2007 Jun;14(2):501-12
Endocrine-related cancer 2007 Jun;14(2):501-12
Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo.
Mosimann C, Hausmann G, Basler K
Cell 2006 Apr 21;125(2):327-41
Cell 2006 Apr 21;125(2):327-41
The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II.
Yart A, Gstaiger M, Wirbelauer C, Pecnik M, Anastasiou D, Hess D, Krek W
Molecular and cellular biology 2005 Jun;25(12):5052-60
Molecular and cellular biology 2005 Jun;25(12):5052-60
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- Submitted by
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