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LearnABIN1881533
antibody from antibodies-online
Targeting: MBNL1
EXP, EXP35, EXP40, EXP42, KIAA0428, MBNL
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN1881533 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Muscleblind-Like (Drosophila) (MBNL1) (C-Term), (AA 255-284) antibody
- Antibody type
- Polyclonal
- Antigen
- This MBNL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-284 amino acids from the C-terminal region of human MBNL1.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term,AA 255-284
- Antibody clone number
- RB42214
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references Muscleblind-like 1 (Mbnl1) promotes insulin receptor exon 11 inclusion via binding to a downstream evolutionarily conserved intronic enhancer.
A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding.
Ribonuclear inclusions and MBNL1 nuclear sequestration do not affect myoblast differentiation but alter gene splicing in myotonic dystrophy type 2.
Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1.
Sen S, Talukdar I, Liu Y, Tam J, Reddy S, Webster NJ
The Journal of biological chemistry 2010 Aug 13;285(33):25426-37
The Journal of biological chemistry 2010 Aug 13;285(33):25426-37
A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding.
Arambula JF, Ramisetty SR, Baranger AM, Zimmerman SC
Proceedings of the National Academy of Sciences of the United States of America 2009 Sep 22;106(38):16068-73
Proceedings of the National Academy of Sciences of the United States of America 2009 Sep 22;106(38):16068-73
Ribonuclear inclusions and MBNL1 nuclear sequestration do not affect myoblast differentiation but alter gene splicing in myotonic dystrophy type 2.
Cardani R, Baldassa S, Botta A, Rinaldi F, Novelli G, Mancinelli E, Meola G
Neuromuscular disorders : NMD 2009 May;19(5):335-43
Neuromuscular disorders : NMD 2009 May;19(5):335-43
Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1.
Teplova M, Patel DJ
Nature structural & molecular biology 2008 Dec;15(12):1343-51
Nature structural & molecular biology 2008 Dec;15(12):1343-51
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- MBNL1 Antibody (C-term) (ABIN1881533) western blot analysis in Jurkat cell line lysates (35 μg/lane). This demonstrates the MBNL1 antibody detected the MBNL1 protein (arrow).
