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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [27]
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- Immunohistochemistry [1]
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- Product number
- 21048-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- GLUT4 antibody
- Antibody type
- Polyclonal
- Description
- GLUT4 antibody (Cat. #21048-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references 2-Methoxyestradiol ameliorates doxorubicin-induced cardiotoxicity by regulating the expression of GLUT4 and CPT-1B in female rats.
Myricanol improves metabolic profiles in dexamethasone induced lipid and protein metabolism disorders in mice.
The lysosomal LAMTOR / Ragulator complex is essential for nutrient homeostasis in brown adipose tissue.
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Up-Regulation of Glycogen Synthesis and Degradation Enzyme Level Maintained Myocardial Glycogen in Huddling Brandt's Voles Under Cool Environments.
Ang-(1-7) protects skeletal muscle function in aged mice.
Downregulation of GLUT3 impairs STYK1/NOK-mediated metabolic reprogramming and proliferation in NIH-3T3 cells.
RNA-seq reveals novel cancer-selective and disease subtype-independent mechanistic targets of withaferin A in human breast cancer cells.
Humanin Alleviates Insulin Resistance in Polycystic Ovary Syndrome: A Human and Rat Model-Based Study.
FGF19 protects skeletal muscle against obesity-induced muscle atrophy, metabolic derangement and abnormal irisin levels via the AMPK/SIRT-1/PGC-α pathway.
3-Chloro-1, 2-propanediol inhibits autophagic flux by impairment of lysosomal function in HepG2 cells.
AT1-receptor autoantibody exposure in utero contributes to cardiac dysfunction and increased glycolysis in fetal mice.
Deoxyelephantopin suppresses hepatic stellate cells activation associated with inhibition of aerobic glycolysis via hedgehog pathway.
Functional genetic variants of RUVBL1 predict overall survival of Chinese patients with epithelial ovarian cancer.
Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer.
Trehalose intake and exercise upregulate a glucose transporter, GLUT8, in the brain.
Effect of CAPE-pNO(2) against type 2 diabetes mellitus via the AMPK/GLUT4/ GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice.
Reversal of the Warburg phenomenon in chemoprevention of prostate cancer by sulforaphane.
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
Bufalin inhibits glycolysis-induced cell growth and proliferation through the suppression of Integrin β2/FAK signaling pathway in ovarian cancer.
PGC-1α Participates in the Protective Effect of Chronic Intermittent Hypobaric Hypoxia on Cardiomyocytes.
Long non‑coding RNA urothelial cancer associated 1 regulates radioresistance via the hexokinase 2/glycolytic pathway in cervical cancer.
Qing brick tea (QBT) aqueous extract protects monosodium glutamate-induced obese mice against metabolic syndrome and involves up-regulation Transcription Factor Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) antioxidant pathway.
The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer.
Fructose‑1,6‑bisphosphatase‑1 decrease may promote carcinogenesis and chemoresistance in cervical cancer.
Cisplatin suppresses the growth and proliferation of breast and cervical cancer cell lines by inhibiting integrin β5-mediated glycolysis.
ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.
Sobhy MH, Ismail A, Abdel-Hamid MS, Wagih M, Kamel M
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):7129-7139
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):7129-7139
Myricanol improves metabolic profiles in dexamethasone induced lipid and protein metabolism disorders in mice.
Li T, Hu X, Fan L, Yang Y, He K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116557
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116557
The lysosomal LAMTOR / Ragulator complex is essential for nutrient homeostasis in brown adipose tissue.
Liebscher G, Vujic N, Schreiber R, Heine M, Krebiehl C, Duta-Mare M, Lamberti G, de Smet CH, Hess MW, Eichmann TO, Hölzl S, Scheja L, Heeren J, Kratky D, Huber LA
Molecular metabolism 2023 May;71:101705
Molecular metabolism 2023 May;71:101705
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Zhao K, Huang X, Zhao W, Lu B, Yang Z
Development (Cambridge, England) 2022 Mar 15;149(6)
Development (Cambridge, England) 2022 Mar 15;149(6)
Up-Regulation of Glycogen Synthesis and Degradation Enzyme Level Maintained Myocardial Glycogen in Huddling Brandt's Voles Under Cool Environments.
Xu JH, Wang Z, Mou JJ, Wang CL, Huang WM, Xue HL, Wu M, Chen L, Xu LX
Frontiers in physiology 2021;12:593129
Frontiers in physiology 2021;12:593129
Ang-(1-7) protects skeletal muscle function in aged mice.
Li Y, Song J, Jiang Y, Yang X, Cao L, Xiao C, Li S, Dong B, Huang X
BMC musculoskeletal disorders 2021 Sep 21;22(1):809
BMC musculoskeletal disorders 2021 Sep 21;22(1):809
Downregulation of GLUT3 impairs STYK1/NOK-mediated metabolic reprogramming and proliferation in NIH-3T3 cells.
Shi W, Fu Y, Wang Y
Oncology letters 2021 Jul;22(1):527
Oncology letters 2021 Jul;22(1):527
RNA-seq reveals novel cancer-selective and disease subtype-independent mechanistic targets of withaferin A in human breast cancer cells.
Hahm ER, Kim SH, Singh KB, Singh SV
Molecular carcinogenesis 2021 Jan;60(1):3-14
Molecular carcinogenesis 2021 Jan;60(1):3-14
Humanin Alleviates Insulin Resistance in Polycystic Ovary Syndrome: A Human and Rat Model-Based Study.
Wang Y, Zeng Z, Zhao S, Tang L, Yan J, Li N, Zou L, Fan X, Xu C, Huang J, Xia W, Zhu C, Rao M
Endocrinology 2021 Aug 1;162(8)
Endocrinology 2021 Aug 1;162(8)
FGF19 protects skeletal muscle against obesity-induced muscle atrophy, metabolic derangement and abnormal irisin levels via the AMPK/SIRT-1/PGC-α pathway.
Guo A, Li K, Tian HC, Fan Z, Chen QN, Yang YF, Yu J, Wu YX, Xiao Q
Journal of cellular and molecular medicine 2021 Apr;25(7):3585-3600
Journal of cellular and molecular medicine 2021 Apr;25(7):3585-3600
3-Chloro-1, 2-propanediol inhibits autophagic flux by impairment of lysosomal function in HepG2 cells.
Lu J, Lu J, Chen Y, Feng Z, Liu S, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111575
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111575
AT1-receptor autoantibody exposure in utero contributes to cardiac dysfunction and increased glycolysis in fetal mice.
Bai L, Wang M, Zhang S, Yue M, Guo Y, Wang P, Liu H
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1373-1381
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1373-1381
Deoxyelephantopin suppresses hepatic stellate cells activation associated with inhibition of aerobic glycolysis via hedgehog pathway.
Gao W, Sun J, Wang F, Lu Y, Wen C, Bian Q, Wu H
Biochemical and biophysical research communications 2019 Sep 3;516(4):1222-1228
Biochemical and biophysical research communications 2019 Sep 3;516(4):1222-1228
Functional genetic variants of RUVBL1 predict overall survival of Chinese patients with epithelial ovarian cancer.
Li H, Tong X, Xu Y, Wang M, Dai H, Shi T, Sun M, Chen K, Cheng X, Wei Q
Carcinogenesis 2019 Oct 16;40(10):1209-1219
Carcinogenesis 2019 Oct 16;40(10):1209-1219
Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer.
Cao D, Qi Z, Pang Y, Li H, Xie H, Wu J, Huang Y, Zhu Y, Shen Y, Zhu Y, Dai B, Hu X, Ye D, Wang Z
Cancer research 2019 May 15;79(10):2604-2618
Cancer research 2019 May 15;79(10):2604-2618
Trehalose intake and exercise upregulate a glucose transporter, GLUT8, in the brain.
Narita H, Tanji K, Miki Y, Mori F, Wakabayashi K
Biochemical and biophysical research communications 2019 Jun 30;514(3):672-677
Biochemical and biophysical research communications 2019 Jun 30;514(3):672-677
Effect of CAPE-pNO(2) against type 2 diabetes mellitus via the AMPK/GLUT4/ GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice.
Li S, Huang Q, Zhang L, Qiao X, Zhang Y, Tang F, Li Z
European journal of pharmacology 2019 Jun 15;853:1-10
European journal of pharmacology 2019 Jun 15;853:1-10
Reversal of the Warburg phenomenon in chemoprevention of prostate cancer by sulforaphane.
Singh KB, Hahm ER, Alumkal JJ, Foley LM, Hitchens TK, Shiva SS, Parikh RA, Jacobs BL, Singh SV
Carcinogenesis 2019 Dec 31;40(12):1545-1556
Carcinogenesis 2019 Dec 31;40(12):1545-1556
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
Fujimoto BA, Young M, Carter L, Pang APS, Corley MJ, Fogelgren B, Polgar N
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
Bufalin inhibits glycolysis-induced cell growth and proliferation through the suppression of Integrin β2/FAK signaling pathway in ovarian cancer.
Li H, Hu S, Pang Y, Li M, Chen L, Liu F, Liu M, Wang Z, Cheng X
American journal of cancer research 2018;8(7):1288-1296
American journal of cancer research 2018;8(7):1288-1296
PGC-1α Participates in the Protective Effect of Chronic Intermittent Hypobaric Hypoxia on Cardiomyocytes.
Gu S, Hua H, Guo X, Jia Z, Zhang Y, Maslov LN, Zhang X, Ma H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(5):1891-1902
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(5):1891-1902
Long non‑coding RNA urothelial cancer associated 1 regulates radioresistance via the hexokinase 2/glycolytic pathway in cervical cancer.
Fan L, Huang C, Li J, Gao T, Lin Z, Yao T
International journal of molecular medicine 2018 Oct;42(4):2247-2259
International journal of molecular medicine 2018 Oct;42(4):2247-2259
Qing brick tea (QBT) aqueous extract protects monosodium glutamate-induced obese mice against metabolic syndrome and involves up-regulation Transcription Factor Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) antioxidant pathway.
Gao W, Xiao C, Hu J, Chen B, Wang C, Cui B, Deng P, Yang J, Deng Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:637-644
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:637-644
The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer.
Jiang W, He T, Liu S, Zheng Y, Xiang L, Pei X, Wang Z, Yang H
Journal of hematology & oncology 2018 Dec 14;11(1):139
Journal of hematology & oncology 2018 Dec 14;11(1):139
Fructose‑1,6‑bisphosphatase‑1 decrease may promote carcinogenesis and chemoresistance in cervical cancer.
Li H, Li M, Pang Y, Liu F, Sheng D, Cheng X
Molecular medicine reports 2017 Dec;16(6):8563-8571
Molecular medicine reports 2017 Dec;16(6):8563-8571
Cisplatin suppresses the growth and proliferation of breast and cervical cancer cell lines by inhibiting integrin β5-mediated glycolysis.
Wang S, Xie J, Li J, Liu F, Wu X, Wang Z
American journal of cancer research 2016;6(5):1108-17
American journal of cancer research 2016;6(5):1108-17
ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.
Dong K, Ni H, Wu M, Tang Z, Halim M, Shi D
Biochemical and biophysical research communications 2016 Aug 5;476(4):204-211
Biochemical and biophysical research communications 2016 Aug 5;476(4):204-211
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human heart tissue slide using 21048-1-AP( GLUT4 Antibody) at dilution of 1:50 (under 10x lens)
- Other comments
- IHC
