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- Antibody Data
- Antigen structure
- References [152]
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- Product number
- 66846-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- GLUT4 antibody
- Antibody type
- Monoclonal
- Description
- GLUT4 antibody (Cat. #66846-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat, pig and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3G7C9
- Vial size
- 20ul, 150ul
Submitted references Bioinspired cardiac-targeted metal-organic framework nanozyme for modulating inflammatory responses in heart failure with preserved ejection fraction.
Echinacoside regulates the IRE1/XBP1 signaling pathway through HSP72 to reduce endoplasmic reticulum stress and improve diabetic kidney disease.
A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis.
Ganoderic Acid A Enhances Glycometabolism in Mouse Gastrocnemius Muscle During Exercise-Induced Fatigue via AMPK/PGC-1α Pathway Activation.
cTnIR193H restrictive cardiomyopathy mice satisfy high-energy metabolic demands through regulating glucose metabolism.
LARS promotes osteosarcoma proliferation through leucine-dependent PRIM2 translation and DNA replication activation.
Oral Rhizoma Coptis Alkaloids Nanoparticle for Treating Diabetes Through Regulating PI3K/Akt Pathways.
Swertia mussotii Franch. Improves skeletal muscle glucose uptake and mitochondrial function via Ampk/Pgc-1α signaling in type 2 diabetes mice.
Anti-Diabetic Effects of Ayanin, a Flavonoid Compound, in STZ/HFD-Induced Diabetic Mice by Upregulating GLUT4 and Suppressing Macrophage-Driven Inflammation in Adipose Tissues.
Hypoxic glycolysis-driven histone lactylation activates NHE7 to promote endometrial cancer progression via COX6C-mediated endoplasmic reticulum stress.
METTL16-m(6)A-PGC-1α axis contributes to exercise-induced mitochondrial adaptations in skeletal muscle of high-fat diet-fed insulin-resistant mice.
miR-432 Exacerbates Obesity-Induced Dysregulation of Glucose and Lipid Homeostasis.
Curcumin ameliorates hepatic insulin resistance by activating PINK1/Parkin-mediated mitophagy.
TangNaikang Formula Alleviates Podocyte Injury in Diabetic Nephropathy by Modulating the SHIP2/PI3K/AKT Pathway.
Superior normalization using total protein for western blot analysis of human adipocytes.
Enhancing Quercetin's Potential: A Nanoliposome Delivery System for High Altitude Pulmonary Edema.
The Role of Placental MFF-Mediated Mitochondrial Fission in Gestational Diabetes Mellitus.
IGFBP5 mediates the therapeutic effect of isoliquiritigenin in myocardial ischemia-reperfusion injury via AKT/GLUT4 regulated insulin resistance.
Genipin attenuates oxidative damage in periodontal tissues by alleviating mitochondrial dysfunction and abnormal glucose uptake through inhibition of UCP2.
L-Theanine Ameliorates Metabolic Dysregulation and Adverse Fetal Outcomes in a Mice Model of Gestational Obesity: Association with FXR/FGF15 Signaling.
Hesperidin Inhibits Oxidative Stress and Apoptosis of Granulosa Cells in Polycystic Ovarian Syndrome Through the JAK2/STAT3 and PI3K/AKT Pathways.
RNF186 controls glucose metabolism in metabolic dysfunction-associated fatty liver disease.
Diosgenin Ameliorates Insulin Resistance in High-Fat Diet-Induced Metabolic Dysfunction-Associated Steatotic Liver Disease Rats via the Adiponectin/ADIPOR1/APPL1 Pathway.
Kang Shuai Lao Pian exerts anti-aging effects by enhancing mitochondrial oxidative metabolism.
A Soluble Receptor for Advanced Glycation End-Products Attenuates Myocardial Ischemia/Reperfusion Injury via Enhancing Glucose Metabolism.
The Novel Dual GIP and GLP-1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism.
Metabolites from the Dendrobium Endophyte Pseudomonas protegens CM-YJ44 Alleviate Insulin Resistance in HepG2 Cells via the IRS1/PI3K/Akt/GSK3β/GLUT4 Pathway.
The inhibition of placental mTOR signaling leads to fetal growth restriction with abnormal glucose metabolism in different anatomical regions of placentas.
Metformin delays the decline in thermogenic function of brown adipose tissue in a mouse model of Hutchinson-Gilford progeria syndrome.
Ginsenoside Rb(1) Ameliorates Heart Failure Ventricular Remodeling by Regulating the Twist1/PGC-1α/PPARα Signaling Pathway.
Ablation of FAM210A in Brown Adipocytes of Mice Exacerbates High-Fat Diet-Induced Metabolic Dysfunction.
Electrical stimulation promotes peripheral nerve regeneration by upregulating glycolysis and oxidative phosphorylation.
Cardioprotective effects of the jiming formula on myocardial metabolism in Mice with myocardial infarction via the AMPK/SIRT1/PGC-1α pathway.
IL-37 inhibited inflammation to improve gestational diabetes mellitus through the GSK3/NF-κB pathway.
Secreted EMC10 inhibits muscle GLUT4 activity and glucose uptake in mice.
Preparation, Characterization, and Functional Evaluation of a Novel Recombinant Hypoglycemic Protein with Multifunctional Effects.
High-Fat Diet-Induced Diabetic Cardiomyopathy in Female Zebrafish: Cardiac Pathology and Functional Decline Mediated by Type 2 Diabetes.
miR-92a-1-5p targets MEF2A to induce insulin resistance in myocardial ischemia/reperfusion injury.
Modified Zuojin pill alleviates gastric precancerous lesions by inhibiting glycolysis through the HIF-1α pathway.
AGDMP1 alleviates insulin resistance by modulating heat shock protein 60-mediated IRS-1/AKT/GLUT4 pathway and adipose inflammation: A potential therapeutic peptide for gestational diabetes mellitus.
Feruloylacetone and Its Analog Demethoxyferuloylacetone Mitigate Obesity-Related Muscle Atrophy and Insulin Resistance in Mice.
Integrative pharmacological analysis of modified Zuojin formula: Inhibiting the HIF-1α-mediated glycolytic pathway in chronic atrophic gastritis.
α-Klotho Supplementation Mitigates Cumulative Exercise-Induced Fatigue via Coordinated NRF2-Mediated Antioxidant Defense and AKT/GS-Driven Hepatic Glycogen Supercompensation in Mice.
Clostridium butyricum ameliorates post-gastrectomy insulin resistance by regulating the mTORC1 signaling pathway through the gut-liver axis.
Adipocyte exosome miR-4472 inhibits glucose uptake in skeletal muscle through downregulation of MEF2D.
Genistein Enhances GLUT4 Expression and Translocation in the Gastrocnemius Muscle and Improves Systemic Glucose Metabolism in Ovariectomized Mice.
An Extensive Analysis of Artemisia integrifolia Linn. on T2DM: Investigating Glycolipid Metabolism, Metabolic Profiling, and Molecular Docking for Potential Functional Food Applications.
Lycium barbarum polysaccharide mitigates high-fat-diet-induced skeletal muscle atrophy by promoting AMPK/PINK1/Parkin-mediated mitophagy.
Effect and underlying mechanism of Huangjing Qianshi decoction in pre-diabetes mouse model.
Metabolic Implications of Elevated Neutrophil Extracellular Traps in Polycystic Ovary Syndrome: A Focus on Hepatic Glycolysis.
Chronic intermittent hypoxia aggravated diabetic cardiomyopathy through LKB1/AMPK/Nrf2 signaling pathway.
Akt1 deficiency does not affect fiber type composition or mitochondrial protein expression in skeletal muscle of male mice.
Epicatechin and β-Glucan from Whole Highland Barley Grain Synergistic Benefit on Attenuating Hyperglycemia via Improving Hepatic Glucose Metabolism in Diabetic C57BL/6J Mice.
Procyanidin B1 and p-coumaric acid from whole highland barley ameliorated HFD-induced impaired glucose tolerance via small intestinal barrier and hepatic glucose metabolism.
Sulforaphane reverses the enhanced NSCLC metastasis by regulating the miR-7-5p/c-Myc/LDHA axis in the acidic tumor microenvironment.
Effective Prevention and Treatment of Acute Leukemias in Mice by Activation of Thermogenic Adipose Tissues.
Interplay of co-cultured chimeric adipose and gingival tissues exacerbates inflammatory dysfunction relevant to periodontal and metabolic conditions.
GDE5/Gpcpd1 activity determines phosphatidylcholine composition in skeletal muscle and regulates contractile force in mice.
Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells.
FGF19 Promotes the Proliferation and Insulin Secretion from Human Pancreatic β Cells Via the IRS1/GLUT4 Pathway.
Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast-twitch muscle in rats.
Naringenin enhances the efficacy of ferroptosis inducers by attenuating aerobic glycolysis by activating the AMPK-PGC1α signalling axis in liver cancer.
Bergenin alleviates proliferative arterial diseases by modulating glucose metabolism in vascular smooth muscle cells.
FERMT1 suppression induces anti-tumor effects and reduces stemness in glioma cancer cells.
GPR30 selective agonist G-1 induced insulin resistance in ovariectomized mice on high fat diet and its mechanism.
Dietary supplementation with inulin improves burn-induced skeletal muscle atrophy by regulating gut microbiota disorders.
Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells.
N1-methylnicotinamide impairs gestational glucose tolerance in mice.
Protein kinase N1 deficiency results in upregulation of cerebral energy metabolism and is highly protective in in vivo and in vitro stroke models.
Aerobic exercise attenuates high-fat diet-induced glycometabolism impairments in skeletal muscle of rat: role of EGR-1/PTP1B signaling pathway.
Single-cell view and a novel protective macrophage subset in perivascular adipose tissue in T2DM.
Puerarin Attenuates Insulin Resistance by Inhibiting Endoplasmic Reticulum Stress and Suppresses Inflammation by Modulating the JNK and IKKβ/NF-κB Pathways in Epididymal White Adipose Tissue of Mice on a High-Fat Diet.
Permethrin exposure impacts zebrafish lipid metabolism via the KRAS-PPAR-GLUT signaling pathway, which is mediated by oxidative stress.
Vitamin D(3) improves glucose metabolism and attenuates inflammation in prediabetic human and mice.
Extract of Phyllanthus emblica L. fruit stimulates basal glucose uptake and ameliorates palmitate-induced insulin resistance through AMPK activation in C2C12 myotubes.
Modulatory Effects of Lactobacillus paracasei-Fermented Turmeric on Metabolic Dysregulation and Gut Microbiota in High-Fat Diet-Induced Obesity in Mice.
Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle.
Neonatal resveratrol administration promotes skeletal muscle growth and insulin sensitivity in intrauterine growth-retarded suckling piglets associated with activation of FGF21-AMPKα pathway.
Pancreatic Cancer-Derived Exosomal miR-Let-7b-5p Stimulates Insulin Resistance in Skeletal Muscle Cells Through RNF20/STAT3/FOXO1 Axis Regulation.
Protective effect of heat-processed Gynostemma pentaphyllum on high fat diet-induced glucose metabolic disorders mice.
Icariin-Curcumol promotes docetaxel sensitivity in prostate cancer through modulation of the PI3K-Akt signaling pathway and the Warburg effect.
A cardiac amino-terminal GRK2 peptide inhibits insulin resistance yet enhances maladaptive cardiovascular and brown adipose tissue remodeling in females during diet-induced obesity.
Ginsenoside F4 Alleviates Skeletal Muscle Insulin Resistance by Regulating PTP1B in Type II Diabetes Mellitus.
Identification of Potential Mechanisms of Rk1 Combination with Rg5 in the Treatment of Type II Diabetes Mellitus by Integrating Network Pharmacology and Experimental Validation.
Depressed Proximal Glycolysis in Myocardium Of Human Heart Failure with Preserved Ejection Fraction.
FAM210A is essential for cold-induced mitochondrial remodeling in brown adipocytes.
Inhibition of miR-543 alleviates cardiac fibroblast-to-myofibroblast transformation and collagen expression in insulin resistance via targeting PTEN.
The efficacy and mechanism of Angelica sinensis (Oliv.) Diels root aqueous extract based on RNA sequencing and 16S rDNA sequencing in alleviating polycystic ovary syndrome.
NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer.
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement.
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Fatty Acid Induced Hypermethylation in the Slc2a4 Gene in Visceral Adipose Tissue Is Associated to Insulin-Resistance and Obesity.
Chemical Constituents and Hypoglycemic Mechanisms of Dendrobium nobile in Treatment of Type 2 Diabetic Rats by UPLC-ESI-Q-Orbitrap, Network Pharmacology and In Vivo Experimental Verification.
Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice.
Bone marrow mesenchymal stem cell-derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway.
Visceral adipose tissue-directed human kallistatin gene therapy improves adipose tissue remodeling and metabolic health in obese mice.
Chinese herbal medicine alleviates the pathogenesis of polycystic ovary syndrome by improving oxidative stress and glucose metabolism via mitochondrial Sirtuin 3 signaling.
Deficiency of S100A9 Alleviates Sepsis-Induced Acute Liver Injury through Regulating AKT-AMPK-Dependent Mitochondrial Energy Metabolism.
IDH2, a novel target of OGT, facilitates glucose uptake and cellular bioenergy production via NF-κB signaling to promote colorectal cancer progression.
The Degree of Hydrolysis and Peptide Profile Affect the Anti-Fatigue Activities of Whey Protein Hydrolysates in Promoting Energy Metabolism in Exercise Mice.
BMP4 participates in the pathogenesis of PCOS by regulating glucose metabolism and autophagy in granulosa cells under hyperandrogenic environment.
Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation.
Phenolic Constituents from Black Quinoa Alleviate Insulin Resistance in HepG2 Cells via Regulating IRS1/PI3K/Akt/GLUTs Signaling Pathways.
Biochemical Toxicological Study of Insulin Overdose in Rats: A Forensic Perspective.
Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload.
Isoginkgetin, a potential CDK6 inhibitor, suppresses SLC2A1/GLUT1 enhancer activity to induce AMPK-ULK1-mediated cytotoxic autophagy in hepatocellular carcinoma.
Intermittent fasting attenuates obesity-related atrial fibrillation via SIRT3-mediated insulin resistance mitigation.
Perturbated glucose metabolism augments epithelial cell proinflammatory function in chronic rhinosinusitis.
Alpha-Ketoglutarate Alleviates Neuronal Apoptosis Induced by Central Insulin Resistance through Inhibiting S6K1 Phosphorylation after Subarachnoid Hemorrhage.
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells.
Hyperinsulinemia-induced microglial mitochondrial dynamic and metabolic alterations lead to neuroinflammation in vivo and in vitro.
DPHB, a diarylheptane from Alpinia officinarum Hance, ameliorates insulin resistance: A network pharmacology and in vitro study.
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
A Metabolism-Related Gene Landscape Predicts Prostate Cancer Recurrence and Treatment Response.
Skeletal Muscle Dysfunction in Experimental Pulmonary Hypertension.
A diarylheptanoid compound from Alpinia officinarum Hance ameliorates high glucose-induced insulin resistance by regulating PI3K/AKT-Nrf2-GSK3β signaling pathways in HepG2 cells.
The influence of perinatal maternal exposure to dibutyl phthalate on glucolipid metabolism in adult female offspring.
Dietary N(ε)-(carboxymethyl) lysine affects cardiac glucose metabolism and myocardial remodeling in mice.
Exercise improves high-fat diet-induced metabolic disorder by promoting HDAC5 degradation through the ubiquitin-proteasome system in skeletal muscle.
Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.
Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway.
Elucidation of the interaction effect between dietary fiber and bound polyphenol components on the anti-hyperglycemic activity of tea residue dietary fiber.
Psoralen Suppresses Lipid Deposition by Alleviating Insulin Resistance and Promoting Autophagy in Oleate-Induced L02 Cells.
Remodeling on adipocytic physiology of organophosphorus esters in mature adipocytes.
A novel regulatory mechanism of geniposide for improving glucose homeostasis mediated by circulating RBP4.
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.
Effects of distinct n-6 to n-3 polyunsaturated fatty acid ratios on insulin resistant and AD-like phenotypes in high-fat diets-fed APP/PS1 mice.
Fermented noni (Morinda citrifolia L.) fruit juice improved oxidative stress and insulin resistance under the synergistic effect of Nrf2/ARE pathway and gut flora in db/db mice and HepG2 cells.
α-Pyrones with glucose uptake-stimulatory activity from the twigs of Cryptocarya wrayi.
Mechanism of Electroacupuncture Regulating IRS-1 Phosphorylation in Skeletal Muscle to Improve Insulin Sensitivity.
Activation of Hippocampal IR/IRS-1 Signaling Contributes to the Treatment with Zuogui Jiangtang Jieyu Decoction on the Diabetes-Related Depression.
Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1α Signaling Pathway.
Total Sesquiterpene Glycosides from Loquat Leaves Ameliorate HFD-Induced Insulin Resistance by Modulating IRS-1/GLUT4, TRPV1, and SIRT6/Nrf2 Signaling Pathways.
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
Mechanism of Mongolian Medicine Eerdun Wurile in Improving Postoperative Cognitive Dysfunction Through Activation of the PI3K Signaling Pathway.
DPHC From Alpinia officinarum Ameliorates Oxidative Stress and Insulin Resistance via Activation of Nrf2/ARE Pathway in db/db Mice and High Glucose-Treated HepG2 Cells.
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model.
Effects of endurance training on the expression of host proteins involved in SARS-CoV-2 cell entry in C57BL/6J mouse.
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters.
Magnesium lithospermate B supplementation improved prenatal Bisphenol A exposure-induced metabolic abnormalities in male offspring.
Gliquidone ameliorates hepatic insulin resistance in streptozotocin-induced diabetic Sur1(-/-) rats.
Integrated analysis of long non-coding RNAs and mRNAs associated with malignant transformation of gastrointestinal stromal tumors.
Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export.
ERα down-regulates carbohydrate responsive element binding protein and decreases aerobic glycolysis in liver cancer cells.
AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.
High-fat diet induced discrepant peripheral and central nervous systems insulin resistance in APPswe/PS1dE9 and wild-type C57BL/6J mice.
Metformin ameliorates skeletal muscle atrophy in Grx1 KO mice by regulating intramuscular lipid accumulation and glucose utilization.
Frequent and mild scrotal heat stress in mice epigenetically alters glucose metabolism in the male offspring.
Chlorogenic Acid Stimulates the Thermogenesis of Brown Adipocytes by Promoting the Uptake of Glucose and the Function of Mitochondria.
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Gui Y, Fan X, Xiao K, Xing J, Niu Z, Wang Y, Yuan W, Shen J, Shi Y, Cheng X, Han Y, Li Z, Tang H
Frontiers in bioengineering and biotechnology 2026;14:1744643
Frontiers in bioengineering and biotechnology 2026;14:1744643
Echinacoside regulates the IRE1/XBP1 signaling pathway through HSP72 to reduce endoplasmic reticulum stress and improve diabetic kidney disease.
Geng R, Ma C, Wen L, Dai W, Liu J, Yang J, Hu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158062
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158062
A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis.
Hou Y, Ma Y, Liu Q, Ma D, Tong Y, Xu L, Chu X, Wang J, Liang M, Zhao M, Zhang H, Su Y, Xie J, Wang C, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e09534
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e09534
Ganoderic Acid A Enhances Glycometabolism in Mouse Gastrocnemius Muscle During Exercise-Induced Fatigue via AMPK/PGC-1α Pathway Activation.
Zhu J, Peng F, Zhang L, Guo Y, Liu W, Li J, Shang S, Zhang B, Qiu T
Food science & nutrition 2026 Mar;14(3):e71596
Food science & nutrition 2026 Mar;14(3):e71596
cTnIR193H restrictive cardiomyopathy mice satisfy high-energy metabolic demands through regulating glucose metabolism.
Luo M, Liu L, Yuan W, Quan J, Li M, Tian J
Genes & diseases 2026 Mar;13(2):101784
Genes & diseases 2026 Mar;13(2):101784
LARS promotes osteosarcoma proliferation through leucine-dependent PRIM2 translation and DNA replication activation.
Bai G, Zhang L, Zhao M, Zhang J, Chen W
Journal of experimental & clinical cancer research : CR 2026 Mar 14;45(1)
Journal of experimental & clinical cancer research : CR 2026 Mar 14;45(1)
Oral Rhizoma Coptis Alkaloids Nanoparticle for Treating Diabetes Through Regulating PI3K/Akt Pathways.
Liu Y, Zhu M, Su Q, Liu M, Zhao Z, Ma P
Pharmaceutics 2026 Mar 11;18(3)
Pharmaceutics 2026 Mar 11;18(3)
Swertia mussotii Franch. Improves skeletal muscle glucose uptake and mitochondrial function via Ampk/Pgc-1α signaling in type 2 diabetes mice.
Huang W, Huang Y, Shu Y, Liao S, Chen H, Chu M, Yang K, Liu S, Jiensi A, Tadesse MG, Huang M, Yang X
Journal of ethnopharmacology 2026 Jul 15;366:121625
Journal of ethnopharmacology 2026 Jul 15;366:121625
Anti-Diabetic Effects of Ayanin, a Flavonoid Compound, in STZ/HFD-Induced Diabetic Mice by Upregulating GLUT4 and Suppressing Macrophage-Driven Inflammation in Adipose Tissues.
Lv Y, Wu C, Yang W, Wang C, Huang J, Wang J, Xia X, Wu D, Yang K, Guo Z, Liao S
Food science & nutrition 2026 Jan;14(1):e71429
Food science & nutrition 2026 Jan;14(1):e71429
Hypoxic glycolysis-driven histone lactylation activates NHE7 to promote endometrial cancer progression via COX6C-mediated endoplasmic reticulum stress.
Yang S, Wu T, Cao Z, Chen Z, Ma Y, Wang T, Qian L, Huang X
Apoptosis : an international journal on programmed cell death 2026 Jan 23;31(2):55
Apoptosis : an international journal on programmed cell death 2026 Jan 23;31(2):55
METTL16-m(6)A-PGC-1α axis contributes to exercise-induced mitochondrial adaptations in skeletal muscle of high-fat diet-fed insulin-resistant mice.
Chen C, Jiang C, Xiang Q, Hu Y, Wu H, Huang C, Zhou H, Xu Y, Hou M, Liu W, Han X
BMC biology 2026 Jan 22;24(1):41
BMC biology 2026 Jan 22;24(1):41
miR-432 Exacerbates Obesity-Induced Dysregulation of Glucose and Lipid Homeostasis.
Wang C, Hou Y, Zhang M, Wang J, Chu X, Liang M, Sun C, Xie J, Zhang J, Wang CY
Diabetes 2026 Jan 1;75(1):22-36
Diabetes 2026 Jan 1;75(1):22-36
Curcumin ameliorates hepatic insulin resistance by activating PINK1/Parkin-mediated mitophagy.
Guo Z, Zhang H, Kong Y
Scientific reports 2026 Apr 8;
Scientific reports 2026 Apr 8;
TangNaikang Formula Alleviates Podocyte Injury in Diabetic Nephropathy by Modulating the SHIP2/PI3K/AKT Pathway.
Yang T, Huang Y, Li W, Qin L, Wu Y, Wu L, Liu T
Journal of diabetes research 2025;2025:6568591
Journal of diabetes research 2025;2025:6568591
Superior normalization using total protein for western blot analysis of human adipocytes.
Westerberg LJS, Dedic B, Näslund E, Thorell A, Spalding KL
PloS one 2025;20(7):e0328136
PloS one 2025;20(7):e0328136
Enhancing Quercetin's Potential: A Nanoliposome Delivery System for High Altitude Pulmonary Edema.
Lin L, Shen B, Cui J, Gao Y, Wang L, Yang T, Weng J, Lai C, Tang X, Xiao C, Shen X, Gao Y
Drug design, development and therapy 2025;19:9151-9167
Drug design, development and therapy 2025;19:9151-9167
The Role of Placental MFF-Mediated Mitochondrial Fission in Gestational Diabetes Mellitus.
Wei L, Fang C, Jiang Y, Zhang H, Gao P, Zhou X, Zhu S, Du Y, Su R, Guo L, He M, Wang S, Feng L, Yu J
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:541-554
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:541-554
IGFBP5 mediates the therapeutic effect of isoliquiritigenin in myocardial ischemia-reperfusion injury via AKT/GLUT4 regulated insulin resistance.
Bai J, Yang SY, Yu SM, Cao Y, Ma CH, Hu XY, Chen X, Song YN, Chen HJ
Frontiers in pharmacology 2025;16:1544869
Frontiers in pharmacology 2025;16:1544869
Genipin attenuates oxidative damage in periodontal tissues by alleviating mitochondrial dysfunction and abnormal glucose uptake through inhibition of UCP2.
Deng Y, Fu R, Shang Y, Hu M, Xin X, Hou Y, Yu W, Liu X
Frontiers in pharmacology 2025;16:1446574
Frontiers in pharmacology 2025;16:1446574
L-Theanine Ameliorates Metabolic Dysregulation and Adverse Fetal Outcomes in a Mice Model of Gestational Obesity: Association with FXR/FGF15 Signaling.
Huang L, Li H, Yang W, Huang L, Chen Q, Li S, Zou Z, Zhao L, Zeng Z
Journal of microbiology and biotechnology 2025 Sep 22;35:e2504017
Journal of microbiology and biotechnology 2025 Sep 22;35:e2504017
Hesperidin Inhibits Oxidative Stress and Apoptosis of Granulosa Cells in Polycystic Ovarian Syndrome Through the JAK2/STAT3 and PI3K/AKT Pathways.
Zhang Q, Yang Z, Ou X, Zhang M, Ji R, Wu G
Phytotherapy research : PTR 2025 Nov;39(11):5174-5197
Phytotherapy research : PTR 2025 Nov;39(11):5174-5197
RNF186 controls glucose metabolism in metabolic dysfunction-associated fatty liver disease.
Du J, Du Q, Zhang Y, Gao J, Wang C, Kou B, Jiang Y, Zhao D, Lin J
Cell & bioscience 2025 Nov 28;15(1):164
Cell & bioscience 2025 Nov 28;15(1):164
Diosgenin Ameliorates Insulin Resistance in High-Fat Diet-Induced Metabolic Dysfunction-Associated Steatotic Liver Disease Rats via the Adiponectin/ADIPOR1/APPL1 Pathway.
Sun Y, Yin G, Wang S, Xie N, Meng D, Zhang X, Yu W, Liu H, Jiang W, Wang L, Qi M, Liu D, Zhang X, Zhang F
Journal of agricultural and food chemistry 2025 Nov 26;73(47):30221-30235
Journal of agricultural and food chemistry 2025 Nov 26;73(47):30221-30235
Kang Shuai Lao Pian exerts anti-aging effects by enhancing mitochondrial oxidative metabolism.
Wang X, Zhang K, Ni J, Deng H, Zhao Z, Wang Z, Li L, Chen F, Li T, Liu L, Fan G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157376
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157376
A Soluble Receptor for Advanced Glycation End-Products Attenuates Myocardial Ischemia/Reperfusion Injury via Enhancing Glucose Metabolism.
Wu H, Zhang J, Jiang X, Shen X, Zeng X, Guo C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 15;39(21):e71173
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 15;39(21):e71173
The Novel Dual GIP and GLP-1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism.
Zhang Y, Xie Y, Xia S, Ge X, Li J, Liu F, Jia F, Wang S, Zhou Q, Gao M, Fang W, Zheng C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2411980
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2411980
Metabolites from the Dendrobium Endophyte Pseudomonas protegens CM-YJ44 Alleviate Insulin Resistance in HepG2 Cells via the IRS1/PI3K/Akt/GSK3β/GLUT4 Pathway.
Qin L, Zhou Y, Fan B, Zheng J, Diao R, Liu J, Wang F
Pharmaceuticals (Basel, Switzerland) 2025 May 29;18(6)
Pharmaceuticals (Basel, Switzerland) 2025 May 29;18(6)
The inhibition of placental mTOR signaling leads to fetal growth restriction with abnormal glucose metabolism in different anatomical regions of placentas.
Xu Q, Wang J, Li Y, Lei H, Jin N, Lu J, Qian C, Zhang J, Dong J, Wang X
Placenta 2025 May 2;164:31-40
Placenta 2025 May 2;164:31-40
Metformin delays the decline in thermogenic function of brown adipose tissue in a mouse model of Hutchinson-Gilford progeria syndrome.
Xiang X, Feng Y, Li H, Li W, Li J, Xia Z, Pang H, Wang Z
Experimental gerontology 2025 Mar;201:112702
Experimental gerontology 2025 Mar;201:112702
Ginsenoside Rb(1) Ameliorates Heart Failure Ventricular Remodeling by Regulating the Twist1/PGC-1α/PPARα Signaling Pathway.
Zhou Z, Song Z, Guo X, Wang Q, Li M, Zhang M, Gong M
Pharmaceuticals (Basel, Switzerland) 2025 Mar 30;18(4)
Pharmaceuticals (Basel, Switzerland) 2025 Mar 30;18(4)
Ablation of FAM210A in Brown Adipocytes of Mice Exacerbates High-Fat Diet-Induced Metabolic Dysfunction.
Qiu J, Khedr MA, Pan M, Ferreira CR, Chen J, Snyder MM, Ajuwon KM, Yue F, Kuang S
Diabetes 2025 Mar 1;74(3):282-294
Diabetes 2025 Mar 1;74(3):282-294
Electrical stimulation promotes peripheral nerve regeneration by upregulating glycolysis and oxidative phosphorylation.
Zhang N, Yao X, Zhang Q, Zhang C, Zheng Q, Wang Y, Shan F
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167804
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167804
Cardioprotective effects of the jiming formula on myocardial metabolism in Mice with myocardial infarction via the AMPK/SIRT1/PGC-1α pathway.
Fan X, Wei X, Wang W, Chai W, Xiao J, Han J, Li F, Guo S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156727
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156727
IL-37 inhibited inflammation to improve gestational diabetes mellitus through the GSK3/NF-κB pathway.
Song M, Zhang G
Diabetology & metabolic syndrome 2025 Jun 5;17(1):193
Diabetology & metabolic syndrome 2025 Jun 5;17(1):193
Secreted EMC10 inhibits muscle GLUT4 activity and glucose uptake in mice.
Jin S, Wu W, Liu S, Wang Y, Huang Q, He K, Ni Y, Chen K, Huang J, Liu L, Dai J, Zhan C, Wang X, Guan Y, Blüher M, Wang X
The Journal of biological chemistry 2025 Jul;301(7):110296
The Journal of biological chemistry 2025 Jul;301(7):110296
Preparation, Characterization, and Functional Evaluation of a Novel Recombinant Hypoglycemic Protein with Multifunctional Effects.
Liu T, Ma X, Duan Z
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18366-18379
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18366-18379
High-Fat Diet-Induced Diabetic Cardiomyopathy in Female Zebrafish: Cardiac Pathology and Functional Decline Mediated by Type 2 Diabetes.
Huang S, Chen Z, Li H, Zou Y, Wang B, Zhao W, Zheng L, Zhou Z, Peng X, Tang C
Nutrients 2025 Jul 2;17(13)
Nutrients 2025 Jul 2;17(13)
miR-92a-1-5p targets MEF2A to induce insulin resistance in myocardial ischemia/reperfusion injury.
Zhou AQ, Cao Y, Song YN, Zhang BF, Chen KY, Yang SY, Chen HJ
Biochemical and biophysical research communications 2025 Jul 1;768:151938
Biochemical and biophysical research communications 2025 Jul 1;768:151938
Modified Zuojin pill alleviates gastric precancerous lesions by inhibiting glycolysis through the HIF-1α pathway.
Liu S, Ji H, Zhang T, Huang J, Yin X, Zhang J, Wang P, Wang F, Tang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156255
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156255
AGDMP1 alleviates insulin resistance by modulating heat shock protein 60-mediated IRS-1/AKT/GLUT4 pathway and adipose inflammation: A potential therapeutic peptide for gestational diabetes mellitus.
Wang S, Zhang Y, Hu S, Bai X, Zhu J, Hao R, Cao Y, Shi Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 31;39(2):e70339
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 31;39(2):e70339
Feruloylacetone and Its Analog Demethoxyferuloylacetone Mitigate Obesity-Related Muscle Atrophy and Insulin Resistance in Mice.
Koh YC, Hsu HW, Ho PY, Lin WS, Hsu KY, Majeed A, Ho CT, Pan MH
Journal of agricultural and food chemistry 2025 Jan 15;73(2):1231-1243
Journal of agricultural and food chemistry 2025 Jan 15;73(2):1231-1243
Integrative pharmacological analysis of modified Zuojin formula: Inhibiting the HIF-1α-mediated glycolytic pathway in chronic atrophic gastritis.
Liu S, Zhang T, Fang L, Hu L, Yin X, Tang X
Journal of ethnopharmacology 2025 Jan 13;339:119136
Journal of ethnopharmacology 2025 Jan 13;339:119136
α-Klotho Supplementation Mitigates Cumulative Exercise-Induced Fatigue via Coordinated NRF2-Mediated Antioxidant Defense and AKT/GS-Driven Hepatic Glycogen Supercompensation in Mice.
Zheng L, Wang Y, Xiao Z, Rao Z, Shi R
International journal of molecular sciences 2025 Dec 30;27(1)
International journal of molecular sciences 2025 Dec 30;27(1)
Clostridium butyricum ameliorates post-gastrectomy insulin resistance by regulating the mTORC1 signaling pathway through the gut-liver axis.
He Z, Xiong H, Cai Y, Chen W, Shi M, Liu L, Wu K, Deng X, Deng X, Chen T
Microbiological research 2025 Aug;297:128154
Microbiological research 2025 Aug;297:128154
Adipocyte exosome miR-4472 inhibits glucose uptake in skeletal muscle through downregulation of MEF2D.
Sun C, Wen X, Chu X, Yuan F, Chen Y, Peng C, Qian M, Mei J, Wang J, Jiang Y, Xu S, Wang C, Li W, Zhang J
Journal of diabetes investigation 2025 Aug;16(8):1382-1397
Journal of diabetes investigation 2025 Aug;16(8):1382-1397
Genistein Enhances GLUT4 Expression and Translocation in the Gastrocnemius Muscle and Improves Systemic Glucose Metabolism in Ovariectomized Mice.
Yang X, Dai K, Wang S
Nutrients 2025 Aug 29;17(17)
Nutrients 2025 Aug 29;17(17)
An Extensive Analysis of Artemisia integrifolia Linn. on T2DM: Investigating Glycolipid Metabolism, Metabolic Profiling, and Molecular Docking for Potential Functional Food Applications.
Liu M, Su F, He Y, Sun M, Bai C, Zhang W, Li B, Sun Y, Wang Q, Kuang H
Foods (Basel, Switzerland) 2025 Aug 24;14(17)
Foods (Basel, Switzerland) 2025 Aug 24;14(17)
Lycium barbarum polysaccharide mitigates high-fat-diet-induced skeletal muscle atrophy by promoting AMPK/PINK1/Parkin-mediated mitophagy.
Ren Y, Wang K, Wu Y, Li J, Ma J, Wang L, Zhang C, Li J, Wei Y, Yang Y
International journal of biological macromolecules 2025 Apr;301:140488
International journal of biological macromolecules 2025 Apr;301:140488
Effect and underlying mechanism of Huangjing Qianshi decoction in pre-diabetes mouse model.
Cai J, Zhu Y, Deng G, Ouyang L, Xiao W, Zhou F, Han Y, Yuan F, Huang L, Li X
BMC complementary medicine and therapies 2025 Apr 23;25(1):151
BMC complementary medicine and therapies 2025 Apr 23;25(1):151
Metabolic Implications of Elevated Neutrophil Extracellular Traps in Polycystic Ovary Syndrome: A Focus on Hepatic Glycolysis.
Lin S, Li Y, Liu W, Du Y, Tao T
Biomolecules 2025 Apr 12;15(4)
Biomolecules 2025 Apr 12;15(4)
Chronic intermittent hypoxia aggravated diabetic cardiomyopathy through LKB1/AMPK/Nrf2 signaling pathway.
Liu B, Si J, Qi K, Li D, Li T, Tang Y, Ji E, Yang S
PloS one 2024;19(3):e0296792
PloS one 2024;19(3):e0296792
Akt1 deficiency does not affect fiber type composition or mitochondrial protein expression in skeletal muscle of male mice.
Miyaji T, Kasuya R, Sawada A, Sawamura D, Kitaoka Y, Miyazaki M
Physiological reports 2024 Sep;12(17):e70048
Physiological reports 2024 Sep;12(17):e70048
Epicatechin and β-Glucan from Whole Highland Barley Grain Synergistic Benefit on Attenuating Hyperglycemia via Improving Hepatic Glucose Metabolism in Diabetic C57BL/6J Mice.
Liu Z, Zhang Z, Tang R, Liu J, Yang Y
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20458-20469
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20458-20469
Procyanidin B1 and p-coumaric acid from whole highland barley ameliorated HFD-induced impaired glucose tolerance via small intestinal barrier and hepatic glucose metabolism.
Liu Z, Yang Y, Xu Y, Zhang Z, Tang R, Liu J, Jiang H, Zhao R
Food & function 2024 Sep 16;15(18):9272-9283
Food & function 2024 Sep 16;15(18):9272-9283
Sulforaphane reverses the enhanced NSCLC metastasis by regulating the miR-7-5p/c-Myc/LDHA axis in the acidic tumor microenvironment.
Shi Z, Zeng H, Zhao B, Zeng C, Zhang F, Liu Z, Kwan HY, Su T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155874
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155874
Effective Prevention and Treatment of Acute Leukemias in Mice by Activation of Thermogenic Adipose Tissues.
Chen R, Cheng T, Xie S, Sun X, Chen M, Zhao S, Ruan Q, Ni X, Rao M, Quan X, Chen K, Zhang S, Cheng T, Xu Y, Chen Y, Yang Y, Cao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(38):e2402332
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(38):e2402332
Interplay of co-cultured chimeric adipose and gingival tissues exacerbates inflammatory dysfunction relevant to periodontal and metabolic conditions.
Xiao L, Mochizuki M, Shimamura N, Sunada K, Nakahara T
Life sciences 2024 Oct 15;355:123009
Life sciences 2024 Oct 15;355:123009
GDE5/Gpcpd1 activity determines phosphatidylcholine composition in skeletal muscle and regulates contractile force in mice.
Aisyah R, Ohshima N, Watanabe D, Nakagawa Y, Sakuma T, Nitschke F, Nakamura M, Sato K, Nakahata K, Yokoyama C, Marchioni CR, Kumrungsee T, Shimizu T, Sotomaru Y, Takeo T, Nakagata N, Izumi T, Miura S, Minassian BA, Yamamoto T, Wada M, Yanaka N
Communications biology 2024 May 20;7(1):604
Communications biology 2024 May 20;7(1):604
Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells.
Liang Z, Ralph-Epps T, Schmidtke MW, Lazcano P, Denis SW, Balážová M, Teixeira da Rosa N Jr, Chakkour M, Hazime S, Ren M, Schlame M, Houtkooper RH, Greenberg ML
Scientific reports 2024 May 20;14(1):11497
Scientific reports 2024 May 20;14(1):11497
FGF19 Promotes the Proliferation and Insulin Secretion from Human Pancreatic β Cells Via the IRS1/GLUT4 Pathway.
Zeng T, Tang X, Bai X, Xiong H
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2024 Mar;132(3):152-161
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2024 Mar;132(3):152-161
Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast-twitch muscle in rats.
Uda M, Yoshihara T, Ichinoseki-Sekine N, Baba T
Physiological reports 2024 Mar;12(5):e15969
Physiological reports 2024 Mar;12(5):e15969
Naringenin enhances the efficacy of ferroptosis inducers by attenuating aerobic glycolysis by activating the AMPK-PGC1α signalling axis in liver cancer.
Li YZ, Deng J, Zhang XD, Li DY, Su LX, Li S, Pan JM, Lu L, Ya JQ, Yang N, Zhou J, Yang LH
Heliyon 2024 Jun 15;10(11):e32288
Heliyon 2024 Jun 15;10(11):e32288
Bergenin alleviates proliferative arterial diseases by modulating glucose metabolism in vascular smooth muscle cells.
Song Y, Deng M, Qiu Y, Cui Y, Zhang B, Xin J, Feng L, Mu X, Cui J, Li H, Sun Y, Yi W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155592
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155592
FERMT1 suppression induces anti-tumor effects and reduces stemness in glioma cancer cells.
Pan Z, Ke C, Zheng H, Guo X, Gao W, Huang X, Chen C, Xiong Y, Zheng S, Zheng F, Hu W
Journal of cancer research and clinical oncology 2024 Jul 8;150(7):338
Journal of cancer research and clinical oncology 2024 Jul 8;150(7):338
GPR30 selective agonist G-1 induced insulin resistance in ovariectomized mice on high fat diet and its mechanism.
Lu C, Liu D, Li M, Shi X, Guan J, Song G, Yin Y, Zheng M, Ma F, Liu G
Biochemical and biophysical research communications 2024 Jul 5;716:150026
Biochemical and biophysical research communications 2024 Jul 5;716:150026
Dietary supplementation with inulin improves burn-induced skeletal muscle atrophy by regulating gut microbiota disorders.
Gao S, Zhao X, Leng Y, Xia Z
Scientific reports 2024 Jan 28;14(1):2328
Scientific reports 2024 Jan 28;14(1):2328
Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells.
Liang Z, Ralph-Epps T, Schmidtke MW, Lazcano P, Denis SW, Balážová M, Chakkour M, Hazime S, Ren M, Schlame M, Houtkooper RH, Greenberg ML
bioRxiv : the preprint server for biology 2024 Feb 4;
bioRxiv : the preprint server for biology 2024 Feb 4;
N1-methylnicotinamide impairs gestational glucose tolerance in mice.
Wei X, Tan Y, Huang J, Dong X, Feng W, Liu T, Yang Z, Yang G, Luo X
Journal of molecular endocrinology 2024 Feb 1;72(2)
Journal of molecular endocrinology 2024 Feb 1;72(2)
Protein kinase N1 deficiency results in upregulation of cerebral energy metabolism and is highly protective in in vivo and in vitro stroke models.
Zur Nedden S, Safari MS, Weber D, Kuenkel L, Garmsiri C, Lang L, Orset C, Freret T, Haelewyn B, Hotze M, Kwiatkowski M, Sarg B, Faserl K, Savic D, Skvortsova II, Krogsdam A, Carollo S, Trajanoski Z, Oberacher H, Zlotek D, Ostermaier F, Cameron A, Baier G, Baier-Bitterlich G
Metabolism: clinical and experimental 2024 Dec;161:156039
Metabolism: clinical and experimental 2024 Dec;161:156039
Aerobic exercise attenuates high-fat diet-induced glycometabolism impairments in skeletal muscle of rat: role of EGR-1/PTP1B signaling pathway.
Zhang L, Liu X, Hu J, Quan H, Lee SK, Korivi M, Wang L, Li T, Li W
Nutrition & metabolism 2024 Dec 31;21(1):113
Nutrition & metabolism 2024 Dec 31;21(1):113
Single-cell view and a novel protective macrophage subset in perivascular adipose tissue in T2DM.
Li J, Tian Z, Zhang T, Jin J, Zhang X, Xie P, Lin H, Gu J, Wu Y, Wang X, Zhang S, Yan X, Guo D, Wang Z, Zhang Q
Cellular & molecular biology letters 2024 Dec 3;29(1):148
Cellular & molecular biology letters 2024 Dec 3;29(1):148
Puerarin Attenuates Insulin Resistance by Inhibiting Endoplasmic Reticulum Stress and Suppresses Inflammation by Modulating the JNK and IKKβ/NF-κB Pathways in Epididymal White Adipose Tissue of Mice on a High-Fat Diet.
Sun J, Liu Y, Zhang J, Shi H, Jiang R, Guo M, Liu Y, Liu B, Wang N, Ma R, Zhang D, Zhang F, Wang S, Wu Y
Molecular nutrition & food research 2024 Aug;68(16):e2400003
Molecular nutrition & food research 2024 Aug;68(16):e2400003
Permethrin exposure impacts zebrafish lipid metabolism via the KRAS-PPAR-GLUT signaling pathway, which is mediated by oxidative stress.
Khan A, Khan B, Hussain S, Wang Y, Mai W, Hou Y
Aquatic toxicology (Amsterdam, Netherlands) 2024 Aug;273:107021
Aquatic toxicology (Amsterdam, Netherlands) 2024 Aug;273:107021
Vitamin D(3) improves glucose metabolism and attenuates inflammation in prediabetic human and mice.
Zhang Y, Ni P, Miao Y, Chen H, Tang L, Song H, Li W, Li X
The Journal of nutritional biochemistry 2024 Aug;130:109659
The Journal of nutritional biochemistry 2024 Aug;130:109659
Extract of Phyllanthus emblica L. fruit stimulates basal glucose uptake and ameliorates palmitate-induced insulin resistance through AMPK activation in C2C12 myotubes.
Li HY, Li CF, Liu CH, Chen SC, Liu YF, Lv QH, Zhang W
BMC complementary medicine and therapies 2024 Aug 2;24(1):296
BMC complementary medicine and therapies 2024 Aug 2;24(1):296
Modulatory Effects of Lactobacillus paracasei-Fermented Turmeric on Metabolic Dysregulation and Gut Microbiota in High-Fat Diet-Induced Obesity in Mice.
Lin WS, Hwang SE, Koh YC, Ho PY, Pan MH
Journal of agricultural and food chemistry 2024 Aug 14;72(32):17924-17937
Journal of agricultural and food chemistry 2024 Aug 14;72(32):17924-17937
Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle.
Tamura Y, Jee E, Kouzaki K, Kotani T, Nakazato K
The Journal of physiology 2024 Apr;602(7):1313-1340
The Journal of physiology 2024 Apr;602(7):1313-1340
Neonatal resveratrol administration promotes skeletal muscle growth and insulin sensitivity in intrauterine growth-retarded suckling piglets associated with activation of FGF21-AMPKα pathway.
Bai G, Chen J, Liu Y, Chen J, Yan H, You J, Zou T
Journal of the science of food and agriculture 2024 Apr;104(6):3719-3728
Journal of the science of food and agriculture 2024 Apr;104(6):3719-3728
Pancreatic Cancer-Derived Exosomal miR-Let-7b-5p Stimulates Insulin Resistance in Skeletal Muscle Cells Through RNF20/STAT3/FOXO1 Axis Regulation.
Wang L, Li X, Wu J, Tang Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:3133-3145
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:3133-3145
Protective effect of heat-processed Gynostemma pentaphyllum on high fat diet-induced glucose metabolic disorders mice.
Xie JB, Xie P, Guo M, Li FF, Xiao MY, Qi YS, Pei WJ, Luo HT, Gu YL, Piao XL
Frontiers in pharmacology 2023;14:1215150
Frontiers in pharmacology 2023;14:1215150
Icariin-Curcumol promotes docetaxel sensitivity in prostate cancer through modulation of the PI3K-Akt signaling pathway and the Warburg effect.
Xu W, Ding J, Kuang S, Li B, Sun T, Zhu C, Liu J, Zhu L, Li Y, Sheng W
Cancer cell international 2023 Sep 2;23(1):190
Cancer cell international 2023 Sep 2;23(1):190
A cardiac amino-terminal GRK2 peptide inhibits insulin resistance yet enhances maladaptive cardiovascular and brown adipose tissue remodeling in females during diet-induced obesity.
Manaserh IH, Bledzka KM, Ampong I, Junker A, Grondolsky J, Schumacher SM
Journal of molecular and cellular cardiology 2023 Oct;183:81-97
Journal of molecular and cellular cardiology 2023 Oct;183:81-97
Ginsenoside F4 Alleviates Skeletal Muscle Insulin Resistance by Regulating PTP1B in Type II Diabetes Mellitus.
Zhao Y, Liu Y, Deng J, Zhu C, Ma X, Jiang M, Fan D
Journal of agricultural and food chemistry 2023 Oct 4;71(39):14263-14275
Journal of agricultural and food chemistry 2023 Oct 4;71(39):14263-14275
Identification of Potential Mechanisms of Rk1 Combination with Rg5 in the Treatment of Type II Diabetes Mellitus by Integrating Network Pharmacology and Experimental Validation.
Liu Y, Zhang J, An C, Liu C, Zhang Q, Ding H, Ma S, Xue W
International journal of molecular sciences 2023 Oct 2;24(19)
International journal of molecular sciences 2023 Oct 2;24(19)
Depressed Proximal Glycolysis in Myocardium Of Human Heart Failure with Preserved Ejection Fraction.
Koleini N, Meddeb M, Keykhaei M, Kwon S, Zhao L, Hahn V, Sharma K, Pearce EL, Kass DA
medRxiv : the preprint server for health sciences 2023 Oct 2;
medRxiv : the preprint server for health sciences 2023 Oct 2;
FAM210A is essential for cold-induced mitochondrial remodeling in brown adipocytes.
Qiu J, Yue F, Zhu P, Chen J, Xu F, Zhang L, Kim KH, Snyder MM, Luo N, Xu HW, Huang F, Tao WA, Kuang S
Nature communications 2023 Oct 10;14(1):6344
Nature communications 2023 Oct 10;14(1):6344
Inhibition of miR-543 alleviates cardiac fibroblast-to-myofibroblast transformation and collagen expression in insulin resistance via targeting PTEN.
Tan YM, Cao LY, Jiao YQ, Han L, Tang MX, Wang ZH, Zhang W, Zhong M, Zhang L
Molecular and cellular endocrinology 2023 Oct 1;576:111996
Molecular and cellular endocrinology 2023 Oct 1;576:111996
The efficacy and mechanism of Angelica sinensis (Oliv.) Diels root aqueous extract based on RNA sequencing and 16S rDNA sequencing in alleviating polycystic ovary syndrome.
Gao Y, Mo S, Cao H, Zhi Y, Ma X, Huang Z, Li B, Wu J, Zhang K, Jin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155013
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155013
NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer.
Chen X, Hao Y, Liu Y, Zhong S, You Y, Ao K, Chong T, Luo X, Yin M, Ye M, He H, Lu A, Chen J, Li X, Zhang J, Guo X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2302705
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2302705
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement.
Zheng P, Zhang Q, Ma W, Hu R, Gu Y, Bian Z, Yang D, Chen X, Wu H
European journal of pharmacology 2023 Nov 15;959:176085
European journal of pharmacology 2023 Nov 15;959:176085
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Wu SA, Shen C, Wei X, Zhang X, Wang S, Chen X, Torres M, Lu Y, Lin LL, Wang HH, Hunter AH, Fang D, Sun S, Ivanova MI, Lin Y, Qi L
Nature communications 2023 May 30;14(1):3132
Nature communications 2023 May 30;14(1):3132
Fatty Acid Induced Hypermethylation in the Slc2a4 Gene in Visceral Adipose Tissue Is Associated to Insulin-Resistance and Obesity.
Britsemmer JH, Krause C, Taege N, Geißler C, Lopez-Alcantara N, Schmidtke L, Naujack AM, Wagner J, Wolter S, Mann O, Kirchner H
International journal of molecular sciences 2023 Mar 29;24(7)
International journal of molecular sciences 2023 Mar 29;24(7)
Chemical Constituents and Hypoglycemic Mechanisms of Dendrobium nobile in Treatment of Type 2 Diabetic Rats by UPLC-ESI-Q-Orbitrap, Network Pharmacology and In Vivo Experimental Verification.
Li Z, Zeng M, Geng K, Lai D, Xu Z, Zhou W
Molecules (Basel, Switzerland) 2023 Mar 16;28(6)
Molecules (Basel, Switzerland) 2023 Mar 16;28(6)
Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice.
Han S, He Z, Hu X, Li X, Zheng K, Huang Y, Xiao P, Xie Q, Ni J, Liu Q
Antioxidants (Basel, Switzerland) 2023 Mar 15;12(3)
Antioxidants (Basel, Switzerland) 2023 Mar 15;12(3)
Bone marrow mesenchymal stem cell-derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway.
Shi H, Hao X, Sun Y, Zhang H, Zhao Y, Wang B, Lu J, Hou W, Yan Y, Yu X, Xue L, Luo X, Wang H
FEBS open bio 2023 Jun;13(6):1015-1026
FEBS open bio 2023 Jun;13(6):1015-1026
Visceral adipose tissue-directed human kallistatin gene therapy improves adipose tissue remodeling and metabolic health in obese mice.
Wu Y, Jiang Y, Guo JQ, Yang ZW, Carvalho A, Qian LL, Ji JJ, Ji ZJ, Ma GS, Yao YY
Cellular signalling 2023 Jun;106:110637
Cellular signalling 2023 Jun;106:110637
Chinese herbal medicine alleviates the pathogenesis of polycystic ovary syndrome by improving oxidative stress and glucose metabolism via mitochondrial Sirtuin 3 signaling.
Zhang Q, Ren J, Wang F, Li M, Pan M, Zhang H, Qu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154556
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154556
Deficiency of S100A9 Alleviates Sepsis-Induced Acute Liver Injury through Regulating AKT-AMPK-Dependent Mitochondrial Energy Metabolism.
Zhang Y, Wu F, Teng F, Guo S, Li H
International journal of molecular sciences 2023 Jan 20;24(3)
International journal of molecular sciences 2023 Jan 20;24(3)
IDH2, a novel target of OGT, facilitates glucose uptake and cellular bioenergy production via NF-κB signaling to promote colorectal cancer progression.
He X, Wu N, Li R, Zhang H, Zhao Y, Nie Y, Wu J
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):145-164
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):145-164
The Degree of Hydrolysis and Peptide Profile Affect the Anti-Fatigue Activities of Whey Protein Hydrolysates in Promoting Energy Metabolism in Exercise Mice.
Zhao C, Gong Y, Zheng L, Zhao M
Journal of agricultural and food chemistry 2023 Feb 15;71(6):3010-3021
Journal of agricultural and food chemistry 2023 Feb 15;71(6):3010-3021
BMP4 participates in the pathogenesis of PCOS by regulating glucose metabolism and autophagy in granulosa cells under hyperandrogenic environment.
Gu R, Dai F, Xiang C, Chen J, Yang D, Tan W, Wang Z, Liu H, Cheng Y
The Journal of steroid biochemistry and molecular biology 2023 Dec;235:106410
The Journal of steroid biochemistry and molecular biology 2023 Dec;235:106410
Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation.
Yan SB, Liang H, Zhan P, Zheng H, Zhao QX, Zheng ZJ, Lu HX, Shang GK, Ji XP
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2623-2641
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2623-2641
Phenolic Constituents from Black Quinoa Alleviate Insulin Resistance in HepG2 Cells via Regulating IRS1/PI3K/Akt/GLUTs Signaling Pathways.
Cao M, Wang J, Jiang X, Sun Z, Zhao L, Chen G
Journal of agricultural and food chemistry 2023 Dec 6;71(48):18780-18791
Journal of agricultural and food chemistry 2023 Dec 6;71(48):18780-18791
Biochemical Toxicological Study of Insulin Overdose in Rats: A Forensic Perspective.
Bian C, He X, Wang Q, Zheng Z, Zhang Y, Xiong H, Li Y, Zhao M, Li J
Toxics 2023 Dec 23;12(1)
Toxics 2023 Dec 23;12(1)
Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload.
Qin X, Fu Y, Fan J, Liu B, Liu P, Zhang Y, Jiang T, Zheng Q
Journal of pineal research 2023 Apr;74(3):e12851
Journal of pineal research 2023 Apr;74(3):e12851
Isoginkgetin, a potential CDK6 inhibitor, suppresses SLC2A1/GLUT1 enhancer activity to induce AMPK-ULK1-mediated cytotoxic autophagy in hepatocellular carcinoma.
Yao J, Tang S, Shi C, Lin Y, Ge L, Chen Q, Ou B, Liu D, Miao Y, Xie Q, Tang X, Fei J, Yang G, Tian J, Zeng X
Autophagy 2023 Apr;19(4):1221-1238
Autophagy 2023 Apr;19(4):1221-1238
Intermittent fasting attenuates obesity-related atrial fibrillation via SIRT3-mediated insulin resistance mitigation.
Zhang Y, Gao F, Gong H, Fu Y, Liu B, Qin X, Zheng Q
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166638
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166638
Perturbated glucose metabolism augments epithelial cell proinflammatory function in chronic rhinosinusitis.
Chen CL, Ma J, Lu RY, Wang YT, Zhao JF, Kang YF, Hu JJ, Wang N, Song J, Zhong J, Chen C, Wang H, Liu Z
The Journal of allergy and clinical immunology 2023 Apr;151(4):991-1004.e20
The Journal of allergy and clinical immunology 2023 Apr;151(4):991-1004.e20
Alpha-Ketoglutarate Alleviates Neuronal Apoptosis Induced by Central Insulin Resistance through Inhibiting S6K1 Phosphorylation after Subarachnoid Hemorrhage.
Ding PF, Zhu Q, Sheng B, Yang H, Xu HJ, Tao T, Peng Z, Chen XX, Li XJ, Zhou Y, Zhang HS, Gao YY, Zhuang Z, Hang CH, Li W
Oxidative medicine and cellular longevity 2022;2022:9148257
Oxidative medicine and cellular longevity 2022;2022:9148257
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Zhang YL, Li PB, Han X, Zhang B, Li HH
Oxidative medicine and cellular longevity 2022;2022:6196173
Oxidative medicine and cellular longevity 2022;2022:6196173
Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells.
Lin L, Wang X, Zhao W, Chen Y
Genetics research 2022;2022:1500768
Genetics research 2022;2022:1500768
Hyperinsulinemia-induced microglial mitochondrial dynamic and metabolic alterations lead to neuroinflammation in vivo and in vitro.
Yang X, Xu Y, Gao W, Wang L, Zhao X, Liu G, Fan K, Liu S, Hao H, Qu S, Dong R, Ma X, Ma J
Frontiers in neuroscience 2022;16:1036872
Frontiers in neuroscience 2022;16:1036872
DPHB, a diarylheptane from Alpinia officinarum Hance, ameliorates insulin resistance: A network pharmacology and in vitro study.
Li X, Wen H, Zhang Y, Liu A, Zhang X, Fu M, Pan Y, Xu J, Zhang J
Frontiers in pharmacology 2022;13:956812
Frontiers in pharmacology 2022;13:956812
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
Ye Z, Ma J, Liu Y, Xu B, Dai X, Fu M, Tian T, Sui X, Mo F, Gao S, Zhao D, Zhang D
Frontiers in pharmacology 2022;13:950535
Frontiers in pharmacology 2022;13:950535
A Metabolism-Related Gene Landscape Predicts Prostate Cancer Recurrence and Treatment Response.
Zhou L, Fan R, Luo Y, Zhang C, Jia D, Wang R, Zeng Y, Ren M, Du K, Pan W, Yang J, Tian F, Gu C
Frontiers in immunology 2022;13:837991
Frontiers in immunology 2022;13:837991
Skeletal Muscle Dysfunction in Experimental Pulmonary Hypertension.
Kosmas K, Michael Z, Papathanasiou AE, Spyropoulos F, Adib E, Jasuja R, Christou H
International journal of molecular sciences 2022 Sep 18;23(18)
International journal of molecular sciences 2022 Sep 18;23(18)
A diarylheptanoid compound from Alpinia officinarum Hance ameliorates high glucose-induced insulin resistance by regulating PI3K/AKT-Nrf2-GSK3β signaling pathways in HepG2 cells.
Zhang XG, Liu AX, Zhang YX, Zhou MY, Li XY, Fu MH, Pan YP, Xu J, Zhang JQ
Journal of ethnopharmacology 2022 Sep 15;295:115397
Journal of ethnopharmacology 2022 Sep 15;295:115397
The influence of perinatal maternal exposure to dibutyl phthalate on glucolipid metabolism in adult female offspring.
Zhou K, Cheng R, Zhu M, Yang M, Shen X, Luo X, Ma L, Xu L, Zhang J
Obesity research & clinical practice 2022 Nov-Dec;16(6):500-506
Obesity research & clinical practice 2022 Nov-Dec;16(6):500-506
Dietary N(ε)-(carboxymethyl) lysine affects cardiac glucose metabolism and myocardial remodeling in mice.
Wang ZQ, Sun Z
World journal of diabetes 2022 Nov 15;13(11):972-985
World journal of diabetes 2022 Nov 15;13(11):972-985
Exercise improves high-fat diet-induced metabolic disorder by promoting HDAC5 degradation through the ubiquitin-proteasome system in skeletal muscle.
Huang S, Zheng X, Zhang X, Jin Z, Liu S, Fu L, Niu Y
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Nov 1;47(11):1062-1074
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Nov 1;47(11):1062-1074
Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.
Dai HB, Wang HY, Wang FZ, Qian P, Gao Q, Zhou H, Zhou YB
Acta diabetologica 2022 May;59(5):661-673
Acta diabetologica 2022 May;59(5):661-673
Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway.
Ni J, Liu Z, Jiang M, Li L, Deng J, Wang X, Su J, Zhu Y, He F, Mao J, Gao X, Fan G
Journal of ginseng research 2022 Mar;46(2):235-247
Journal of ginseng research 2022 Mar;46(2):235-247
Elucidation of the interaction effect between dietary fiber and bound polyphenol components on the anti-hyperglycemic activity of tea residue dietary fiber.
Huang H, Chen J, Hu X, Chen Y, Xie J, Ao T, Wang H, Xie J, Yu Q
Food & function 2022 Mar 7;13(5):2710-2728
Food & function 2022 Mar 7;13(5):2710-2728
Psoralen Suppresses Lipid Deposition by Alleviating Insulin Resistance and Promoting Autophagy in Oleate-Induced L02 Cells.
Wang Y, Wang Y, Li F, Zou J, Li X, Xu M, Yu D, Ma Y, Huang W, Sun X, Zhang Y
Cells 2022 Mar 22;11(7)
Cells 2022 Mar 22;11(7)
Remodeling on adipocytic physiology of organophosphorus esters in mature adipocytes.
Liu Y, Le Y, Xu M, Wang W, Chen H, Zhang Q, Wang C
Environmental pollution (Barking, Essex : 1987) 2022 Jul 15;305:119287
Environmental pollution (Barking, Essex : 1987) 2022 Jul 15;305:119287
A novel regulatory mechanism of geniposide for improving glucose homeostasis mediated by circulating RBP4.
Liu J, Song C, Nie C, Sun Y, Wang Y, Xue L, Fan M, Qian H, Wang L, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153862
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153862
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.
Wang P, Li CG, Zhou X, Ding S
Clinical and experimental pharmacology & physiology 2022 Feb;49(2):302-310
Clinical and experimental pharmacology & physiology 2022 Feb;49(2):302-310
Effects of distinct n-6 to n-3 polyunsaturated fatty acid ratios on insulin resistant and AD-like phenotypes in high-fat diets-fed APP/PS1 mice.
Ma X, Guo Y, Xu J, Wang X, Dong S, Gao Y, Van Halm-Lutterodt N, Yuan L
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt B):112207
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt B):112207
Fermented noni (Morinda citrifolia L.) fruit juice improved oxidative stress and insulin resistance under the synergistic effect of Nrf2/ARE pathway and gut flora in db/db mice and HepG2 cells.
Zhang X, Zhang B, Li L, Li X, Zhang J, Chen G
Food & function 2022 Aug 1;13(15):8254-8273
Food & function 2022 Aug 1;13(15):8254-8273
α-Pyrones with glucose uptake-stimulatory activity from the twigs of Cryptocarya wrayi.
Wang XN, Kuang XD, Wang Y, Sun P, He XR, Peng YA, Liu LH, Gu JL, Gan LS, Wang XN, Shu JC, Zhou ZW
Fitoterapia 2022 Apr;158:105144
Fitoterapia 2022 Apr;158:105144
Mechanism of Electroacupuncture Regulating IRS-1 Phosphorylation in Skeletal Muscle to Improve Insulin Sensitivity.
Song S, Li R, Cao B, Zhang J, Kim Y, Kim B, Yu X
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8631475
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8631475
Activation of Hippocampal IR/IRS-1 Signaling Contributes to the Treatment with Zuogui Jiangtang Jieyu Decoction on the Diabetes-Related Depression.
Yang H, Ling J, Meng P, Liu J, Lin X, Li W, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6688723
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6688723
Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1α Signaling Pathway.
Bai Y, Zuo J, Fang X, Ma R, Tian T, Mo F, Mu Q, Zhang Y, Yu N, Bao X, Zhang D, Gao S, Zhao D
Oxidative medicine and cellular longevity 2021;2021:5566053
Oxidative medicine and cellular longevity 2021;2021:5566053
Total Sesquiterpene Glycosides from Loquat Leaves Ameliorate HFD-Induced Insulin Resistance by Modulating IRS-1/GLUT4, TRPV1, and SIRT6/Nrf2 Signaling Pathways.
Wu R, Jian T, Ding X, Lv H, Meng X, Ren B, Li J, Chen J, Li W
Oxidative medicine and cellular longevity 2021;2021:4706410
Oxidative medicine and cellular longevity 2021;2021:4706410
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
Sun N, Meng F, Zhao J, Li X, Li R, Han J, Chen X, Cheng W, Yang X, Kou Y, Zheng K, Yang J, Ikezoe T
International journal of biological sciences 2021;17(5):1302-1314
International journal of biological sciences 2021;17(5):1302-1314
Mechanism of Mongolian Medicine Eerdun Wurile in Improving Postoperative Cognitive Dysfunction Through Activation of the PI3K Signaling Pathway.
Lv Z, Che L, Du Y, Yu J, Su E, Liu H, Chen D
Frontiers in neuroscience 2021;15:769759
Frontiers in neuroscience 2021;15:769759
DPHC From Alpinia officinarum Ameliorates Oxidative Stress and Insulin Resistance via Activation of Nrf2/ARE Pathway in db/db Mice and High Glucose-Treated HepG2 Cells.
Zhang X, Zhang Y, Zhou M, Xie Y, Dong X, Bai F, Zhang J
Frontiers in pharmacology 2021;12:792977
Frontiers in pharmacology 2021;12:792977
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
Zhang Y, Fu Y, Jiang T, Liu B, Sun H, Zhang Y, Fan B, Li X, Qin X, Zheng Q
Frontiers in pharmacology 2021;12:771940
Frontiers in pharmacology 2021;12:771940
DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model.
Tao J, Yu XL, Yuan YJ, Shen X, Liu J, Gu PP, Wang Z, Ma YT, Li GQ
Frontiers in endocrinology 2021;12:723623
Frontiers in endocrinology 2021;12:723623
Effects of endurance training on the expression of host proteins involved in SARS-CoV-2 cell entry in C57BL/6J mouse.
Tamura Y, Jee E, Kouzaki K, Kotani T, Nakazato K
Physiological reports 2021 Sep;9(17):e15014
Physiological reports 2021 Sep;9(17):e15014
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters.
Jiang MJ, Li L, Huang WF, Su J, Li YH, Qu XS, Fan LL
Journal of natural medicines 2021 Sep;75(4):884-892
Journal of natural medicines 2021 Sep;75(4):884-892
Magnesium lithospermate B supplementation improved prenatal Bisphenol A exposure-induced metabolic abnormalities in male offspring.
Huang WC, Liao KY, Hsieh SK, Pan PH, Kuan YH, Liao SL, Chen CJ, Chen WY
Environmental toxicology 2021 Sep;36(9):1932-1943
Environmental toxicology 2021 Sep;36(9):1932-1943
Gliquidone ameliorates hepatic insulin resistance in streptozotocin-induced diabetic Sur1(-/-) rats.
Zhang R, Zhou X, Sheng Q, Zhang Q, Xie T, Xu C, Zou Z, Dong J, Liao L
European journal of pharmacology 2021 Sep 5;906:174221
European journal of pharmacology 2021 Sep 5;906:174221
Integrated analysis of long non-coding RNAs and mRNAs associated with malignant transformation of gastrointestinal stromal tumors.
Yin X, Yin Y, Dai L, Shen C, Chen N, Li J, Cai Z, Jiang Z, Wang J, Zhao Z, Chen X, Deng H, Zhang B
Cell death & disease 2021 Jul 3;12(7):669
Cell death & disease 2021 Jul 3;12(7):669
Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export.
Wang K, Huang W, Chen R, Lin P, Zhang T, Ni YF, Li H, Wu J, Sun XX, Geng JJ, Zhu YM, Nan G, Zhang W, Chen X, Zhu P, Bian H, Chen ZN
Cell metabolism 2021 Jan 5;33(1):160-173.e6
Cell metabolism 2021 Jan 5;33(1):160-173.e6
ERα down-regulates carbohydrate responsive element binding protein and decreases aerobic glycolysis in liver cancer cells.
Lu Y, Tian N, Hu L, Meng J, Feng M, Zhu Y, Zhang P, Li M, Liu Q, Tong L, Tong X, Li Y, Wu L
Journal of cellular and molecular medicine 2021 Apr;25(7):3427-3436
Journal of cellular and molecular medicine 2021 Apr;25(7):3427-3436
AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.
Chen M, Ji C, Yang Q, Gao S, Peng Y, Li Z, Gao X, Li Y, Jiang N, Zhang Y, Bian X, Chen C, Zhang K, Sanchis D, Yan F, Ye J
Clinical science (London, England : 1979) 2020 Sep 18;134(17):2381-2398
Clinical science (London, England : 1979) 2020 Sep 18;134(17):2381-2398
High-fat diet induced discrepant peripheral and central nervous systems insulin resistance in APPswe/PS1dE9 and wild-type C57BL/6J mice.
Guo Y, Ma X, Li P, Dong S, Huang X, Ren X, Yuan L
Aging 2020 Dec 3;13(1):1236-1250
Aging 2020 Dec 3;13(1):1236-1250
Metformin ameliorates skeletal muscle atrophy in Grx1 KO mice by regulating intramuscular lipid accumulation and glucose utilization.
Yang Y, Liao Z, Xiao Q
Biochemical and biophysical research communications 2020 Dec 17;533(4):1226-1232
Biochemical and biophysical research communications 2020 Dec 17;533(4):1226-1232
Frequent and mild scrotal heat stress in mice epigenetically alters glucose metabolism in the male offspring.
Wan X, He X, Liu Q, Wang X, Ding X, Li H
American journal of physiology. Endocrinology and metabolism 2020 Aug 1;319(2):E291-E304
American journal of physiology. Endocrinology and metabolism 2020 Aug 1;319(2):E291-E304
Chlorogenic Acid Stimulates the Thermogenesis of Brown Adipocytes by Promoting the Uptake of Glucose and the Function of Mitochondria.
Han X, Zhang Y, Guo J, You Y, Zhan J, Huang W
Journal of food science 2019 Dec;84(12):3815-3824
Journal of food science 2019 Dec;84(12):3815-3824
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Wang S, Li J, Xie J, Liu F, Duan Y, Wu Y, Huang S, He X, Wang Z, Wu X
Oncogene 2018 Jul;37(30):4164-4180
Oncogene 2018 Jul;37(30):4164-4180
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