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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [81]
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- Product number
- 66846-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- GLUT4 antibody
- Antibody type
- Monoclonal
- Description
- GLUT4 antibody (Cat. #66846-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat, pig and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3G7C9
- Vial size
- 20ul, 150ul
Submitted references Chronic intermittent hypoxia aggravated diabetic cardiomyopathy through LKB1/AMPK/Nrf2 signaling pathway.
Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast-twitch muscle in rats.
Bergenin alleviates proliferative arterial diseases by modulating glucose metabolism in vascular smooth muscle cells.
Dietary supplementation with inulin improves burn-induced skeletal muscle atrophy by regulating gut microbiota disorders.
Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells.
Vitamin D(3) improves glucose metabolism and attenuates inflammation in prediabetic human and mice.
Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle.
Neonatal resveratrol administration promotes skeletal muscle growth and insulin sensitivity in intrauterine growth-retarded suckling piglets associated with activation of FGF21-AMPKα pathway.
Pancreatic Cancer-Derived Exosomal miR-Let-7b-5p Stimulates Insulin Resistance in Skeletal Muscle Cells Through RNF20/STAT3/FOXO1 Axis Regulation.
Protective effect of heat-processed Gynostemma pentaphyllum on high fat diet-induced glucose metabolic disorders mice.
Icariin-Curcumol promotes docetaxel sensitivity in prostate cancer through modulation of the PI3K-Akt signaling pathway and the Warburg effect.
Ginsenoside F4 Alleviates Skeletal Muscle Insulin Resistance by Regulating PTP1B in Type II Diabetes Mellitus.
Identification of Potential Mechanisms of Rk1 Combination with Rg5 in the Treatment of Type II Diabetes Mellitus by Integrating Network Pharmacology and Experimental Validation.
Depressed Proximal Glycolysis in Myocardium Of Human Heart Failure with Preserved Ejection Fraction.
FAM210A is essential for cold-induced mitochondrial remodeling in brown adipocytes.
Inhibition of miR-543 alleviates cardiac fibroblast-to-myofibroblast transformation and collagen expression in insulin resistance via targeting PTEN.
The efficacy and mechanism of Angelica sinensis (Oliv.) Diels root aqueous extract based on RNA sequencing and 16S rDNA sequencing in alleviating polycystic ovary syndrome.
NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer.
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement.
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Fatty Acid Induced Hypermethylation in the Slc2a4 Gene in Visceral Adipose Tissue Is Associated to Insulin-Resistance and Obesity.
Chemical Constituents and Hypoglycemic Mechanisms of Dendrobium nobile in Treatment of Type 2 Diabetic Rats by UPLC-ESI-Q-Orbitrap, Network Pharmacology and In Vivo Experimental Verification.
Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice.
Bone marrow mesenchymal stem cell-derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway.
Visceral adipose tissue-directed human kallistatin gene therapy improves adipose tissue remodeling and metabolic health in obese mice.
Chinese herbal medicine alleviates the pathogenesis of polycystic ovary syndrome by improving oxidative stress and glucose metabolism via mitochondrial Sirtuin 3 signaling.
Deficiency of S100A9 Alleviates Sepsis-Induced Acute Liver Injury through Regulating AKT-AMPK-Dependent Mitochondrial Energy Metabolism.
IDH2, a novel target of OGT, facilitates glucose uptake and cellular bioenergy production via NF-κB signaling to promote colorectal cancer progression.
The Degree of Hydrolysis and Peptide Profile Affect the Anti-Fatigue Activities of Whey Protein Hydrolysates in Promoting Energy Metabolism in Exercise Mice.
BMP4 participates in the pathogenesis of PCOS by regulating glucose metabolism and autophagy in granulosa cells under hyperandrogenic environment.
Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation.
Phenolic Constituents from Black Quinoa Alleviate Insulin Resistance in HepG2 Cells via Regulating IRS1/PI3K/Akt/GLUTs Signaling Pathways.
Biochemical Toxicological Study of Insulin Overdose in Rats: A Forensic Perspective.
Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload.
Isoginkgetin, a potential CDK6 inhibitor, suppresses SLC2A1/GLUT1 enhancer activity to induce AMPK-ULK1-mediated cytotoxic autophagy in hepatocellular carcinoma.
Intermittent fasting attenuates obesity-related atrial fibrillation via SIRT3-mediated insulin resistance mitigation.
Perturbated glucose metabolism augments epithelial cell proinflammatory function in chronic rhinosinusitis.
Alpha-Ketoglutarate Alleviates Neuronal Apoptosis Induced by Central Insulin Resistance through Inhibiting S6K1 Phosphorylation after Subarachnoid Hemorrhage.
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells.
Hyperinsulinemia-induced microglial mitochondrial dynamic and metabolic alterations lead to neuroinflammation in vivo and in vitro.
DPHB, a diarylheptane from Alpinia officinarum Hance, ameliorates insulin resistance: A network pharmacology and in vitro study.
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
A Metabolism-Related Gene Landscape Predicts Prostate Cancer Recurrence and Treatment Response.
Skeletal Muscle Dysfunction in Experimental Pulmonary Hypertension.
A diarylheptanoid compound from Alpinia officinarum Hance ameliorates high glucose-induced insulin resistance by regulating PI3K/AKT-Nrf2-GSK3β signaling pathways in HepG2 cells.
The influence of perinatal maternal exposure to dibutyl phthalate on glucolipid metabolism in adult female offspring.
Dietary N(ε)-(carboxymethyl) lysine affects cardiac glucose metabolism and myocardial remodeling in mice.
Exercise improves high-fat diet-induced metabolic disorder by promoting HDAC5 degradation through the ubiquitin-proteasome system in skeletal muscle.
Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.
Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway.
Elucidation of the interaction effect between dietary fiber and bound polyphenol components on the anti-hyperglycemic activity of tea residue dietary fiber.
Psoralen Suppresses Lipid Deposition by Alleviating Insulin Resistance and Promoting Autophagy in Oleate-Induced L02 Cells.
Remodeling on adipocytic physiology of organophosphorus esters in mature adipocytes.
A novel regulatory mechanism of geniposide for improving glucose homeostasis mediated by circulating RBP4.
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.
Effects of distinct n-6 to n-3 polyunsaturated fatty acid ratios on insulin resistant and AD-like phenotypes in high-fat diets-fed APP/PS1 mice.
Fermented noni (Morinda citrifolia L.) fruit juice improved oxidative stress and insulin resistance under the synergistic effect of Nrf2/ARE pathway and gut flora in db/db mice and HepG2 cells.
α-Pyrones with glucose uptake-stimulatory activity from the twigs of Cryptocarya wrayi.
Mechanism of Electroacupuncture Regulating IRS-1 Phosphorylation in Skeletal Muscle to Improve Insulin Sensitivity.
Activation of Hippocampal IR/IRS-1 Signaling Contributes to the Treatment with Zuogui Jiangtang Jieyu Decoction on the Diabetes-Related Depression.
Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1α Signaling Pathway.
Total Sesquiterpene Glycosides from Loquat Leaves Ameliorate HFD-Induced Insulin Resistance by Modulating IRS-1/GLUT4, TRPV1, and SIRT6/Nrf2 Signaling Pathways.
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
Mechanism of Mongolian Medicine Eerdun Wurile in Improving Postoperative Cognitive Dysfunction Through Activation of the PI3K Signaling Pathway.
DPHC From Alpinia officinarum Ameliorates Oxidative Stress and Insulin Resistance via Activation of Nrf2/ARE Pathway in db/db Mice and High Glucose-Treated HepG2 Cells.
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model.
Effects of endurance training on the expression of host proteins involved in SARS-CoV-2 cell entry in C57BL/6J mouse.
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters.
Magnesium lithospermate B supplementation improved prenatal Bisphenol A exposure-induced metabolic abnormalities in male offspring.
Gliquidone ameliorates hepatic insulin resistance in streptozotocin-induced diabetic Sur1(-/-) rats.
Integrated analysis of long non-coding RNAs and mRNAs associated with malignant transformation of gastrointestinal stromal tumors.
Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export.
ERα down-regulates carbohydrate responsive element binding protein and decreases aerobic glycolysis in liver cancer cells.
AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.
High-fat diet induced discrepant peripheral and central nervous systems insulin resistance in APPswe/PS1dE9 and wild-type C57BL/6J mice.
Metformin ameliorates skeletal muscle atrophy in Grx1 KO mice by regulating intramuscular lipid accumulation and glucose utilization.
Frequent and mild scrotal heat stress in mice epigenetically alters glucose metabolism in the male offspring.
Chlorogenic Acid Stimulates the Thermogenesis of Brown Adipocytes by Promoting the Uptake of Glucose and the Function of Mitochondria.
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Liu B, Si J, Qi K, Li D, Li T, Tang Y, Ji E, Yang S
PloS one 2024;19(3):e0296792
PloS one 2024;19(3):e0296792
Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast-twitch muscle in rats.
Uda M, Yoshihara T, Ichinoseki-Sekine N, Baba T
Physiological reports 2024 Mar;12(5):e15969
Physiological reports 2024 Mar;12(5):e15969
Bergenin alleviates proliferative arterial diseases by modulating glucose metabolism in vascular smooth muscle cells.
Song Y, Deng M, Qiu Y, Cui Y, Zhang B, Xin J, Feng L, Mu X, Cui J, Li H, Sun Y, Yi W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155592
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155592
Dietary supplementation with inulin improves burn-induced skeletal muscle atrophy by regulating gut microbiota disorders.
Gao S, Zhao X, Leng Y, Xia Z
Scientific reports 2024 Jan 28;14(1):2328
Scientific reports 2024 Jan 28;14(1):2328
Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells.
Liang Z, Ralph-Epps T, Schmidtke MW, Lazcano P, Denis SW, Balážová M, Chakkour M, Hazime S, Ren M, Schlame M, Houtkooper RH, Greenberg ML
bioRxiv : the preprint server for biology 2024 Feb 4;
bioRxiv : the preprint server for biology 2024 Feb 4;
Vitamin D(3) improves glucose metabolism and attenuates inflammation in prediabetic human and mice.
Zhang Y, Ni P, Miao Y, Chen H, Tang L, Song H, Li W, Li X
The Journal of nutritional biochemistry 2024 Aug;130:109659
The Journal of nutritional biochemistry 2024 Aug;130:109659
Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle.
Tamura Y, Jee E, Kouzaki K, Kotani T, Nakazato K
The Journal of physiology 2024 Apr;602(7):1313-1340
The Journal of physiology 2024 Apr;602(7):1313-1340
Neonatal resveratrol administration promotes skeletal muscle growth and insulin sensitivity in intrauterine growth-retarded suckling piglets associated with activation of FGF21-AMPKα pathway.
Bai G, Chen J, Liu Y, Chen J, Yan H, You J, Zou T
Journal of the science of food and agriculture 2024 Apr;104(6):3719-3728
Journal of the science of food and agriculture 2024 Apr;104(6):3719-3728
Pancreatic Cancer-Derived Exosomal miR-Let-7b-5p Stimulates Insulin Resistance in Skeletal Muscle Cells Through RNF20/STAT3/FOXO1 Axis Regulation.
Wang L, Li X, Wu J, Tang Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:3133-3145
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:3133-3145
Protective effect of heat-processed Gynostemma pentaphyllum on high fat diet-induced glucose metabolic disorders mice.
Xie JB, Xie P, Guo M, Li FF, Xiao MY, Qi YS, Pei WJ, Luo HT, Gu YL, Piao XL
Frontiers in pharmacology 2023;14:1215150
Frontiers in pharmacology 2023;14:1215150
Icariin-Curcumol promotes docetaxel sensitivity in prostate cancer through modulation of the PI3K-Akt signaling pathway and the Warburg effect.
Xu W, Ding J, Kuang S, Li B, Sun T, Zhu C, Liu J, Zhu L, Li Y, Sheng W
Cancer cell international 2023 Sep 2;23(1):190
Cancer cell international 2023 Sep 2;23(1):190
Ginsenoside F4 Alleviates Skeletal Muscle Insulin Resistance by Regulating PTP1B in Type II Diabetes Mellitus.
Zhao Y, Liu Y, Deng J, Zhu C, Ma X, Jiang M, Fan D
Journal of agricultural and food chemistry 2023 Oct 4;71(39):14263-14275
Journal of agricultural and food chemistry 2023 Oct 4;71(39):14263-14275
Identification of Potential Mechanisms of Rk1 Combination with Rg5 in the Treatment of Type II Diabetes Mellitus by Integrating Network Pharmacology and Experimental Validation.
Liu Y, Zhang J, An C, Liu C, Zhang Q, Ding H, Ma S, Xue W
International journal of molecular sciences 2023 Oct 2;24(19)
International journal of molecular sciences 2023 Oct 2;24(19)
Depressed Proximal Glycolysis in Myocardium Of Human Heart Failure with Preserved Ejection Fraction.
Koleini N, Meddeb M, Keykhaei M, Kwon S, Zhao L, Hahn V, Sharma K, Pearce EL, Kass DA
medRxiv : the preprint server for health sciences 2023 Oct 2;
medRxiv : the preprint server for health sciences 2023 Oct 2;
FAM210A is essential for cold-induced mitochondrial remodeling in brown adipocytes.
Qiu J, Yue F, Zhu P, Chen J, Xu F, Zhang L, Kim KH, Snyder MM, Luo N, Xu HW, Huang F, Tao WA, Kuang S
Nature communications 2023 Oct 10;14(1):6344
Nature communications 2023 Oct 10;14(1):6344
Inhibition of miR-543 alleviates cardiac fibroblast-to-myofibroblast transformation and collagen expression in insulin resistance via targeting PTEN.
Tan YM, Cao LY, Jiao YQ, Han L, Tang MX, Wang ZH, Zhang W, Zhong M, Zhang L
Molecular and cellular endocrinology 2023 Oct 1;576:111996
Molecular and cellular endocrinology 2023 Oct 1;576:111996
The efficacy and mechanism of Angelica sinensis (Oliv.) Diels root aqueous extract based on RNA sequencing and 16S rDNA sequencing in alleviating polycystic ovary syndrome.
Gao Y, Mo S, Cao H, Zhi Y, Ma X, Huang Z, Li B, Wu J, Zhang K, Jin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155013
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155013
NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer.
Chen X, Hao Y, Liu Y, Zhong S, You Y, Ao K, Chong T, Luo X, Yin M, Ye M, He H, Lu A, Chen J, Li X, Zhang J, Guo X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2302705
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2302705
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement.
Zheng P, Zhang Q, Ma W, Hu R, Gu Y, Bian Z, Yang D, Chen X, Wu H
European journal of pharmacology 2023 Nov 15;959:176085
European journal of pharmacology 2023 Nov 15;959:176085
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Wu SA, Shen C, Wei X, Zhang X, Wang S, Chen X, Torres M, Lu Y, Lin LL, Wang HH, Hunter AH, Fang D, Sun S, Ivanova MI, Lin Y, Qi L
Nature communications 2023 May 30;14(1):3132
Nature communications 2023 May 30;14(1):3132
Fatty Acid Induced Hypermethylation in the Slc2a4 Gene in Visceral Adipose Tissue Is Associated to Insulin-Resistance and Obesity.
Britsemmer JH, Krause C, Taege N, Geißler C, Lopez-Alcantara N, Schmidtke L, Naujack AM, Wagner J, Wolter S, Mann O, Kirchner H
International journal of molecular sciences 2023 Mar 29;24(7)
International journal of molecular sciences 2023 Mar 29;24(7)
Chemical Constituents and Hypoglycemic Mechanisms of Dendrobium nobile in Treatment of Type 2 Diabetic Rats by UPLC-ESI-Q-Orbitrap, Network Pharmacology and In Vivo Experimental Verification.
Li Z, Zeng M, Geng K, Lai D, Xu Z, Zhou W
Molecules (Basel, Switzerland) 2023 Mar 16;28(6)
Molecules (Basel, Switzerland) 2023 Mar 16;28(6)
Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice.
Han S, He Z, Hu X, Li X, Zheng K, Huang Y, Xiao P, Xie Q, Ni J, Liu Q
Antioxidants (Basel, Switzerland) 2023 Mar 15;12(3)
Antioxidants (Basel, Switzerland) 2023 Mar 15;12(3)
Bone marrow mesenchymal stem cell-derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway.
Shi H, Hao X, Sun Y, Zhang H, Zhao Y, Wang B, Lu J, Hou W, Yan Y, Yu X, Xue L, Luo X, Wang H
FEBS open bio 2023 Jun;13(6):1015-1026
FEBS open bio 2023 Jun;13(6):1015-1026
Visceral adipose tissue-directed human kallistatin gene therapy improves adipose tissue remodeling and metabolic health in obese mice.
Wu Y, Jiang Y, Guo JQ, Yang ZW, Carvalho A, Qian LL, Ji JJ, Ji ZJ, Ma GS, Yao YY
Cellular signalling 2023 Jun;106:110637
Cellular signalling 2023 Jun;106:110637
Chinese herbal medicine alleviates the pathogenesis of polycystic ovary syndrome by improving oxidative stress and glucose metabolism via mitochondrial Sirtuin 3 signaling.
Zhang Q, Ren J, Wang F, Li M, Pan M, Zhang H, Qu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154556
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154556
Deficiency of S100A9 Alleviates Sepsis-Induced Acute Liver Injury through Regulating AKT-AMPK-Dependent Mitochondrial Energy Metabolism.
Zhang Y, Wu F, Teng F, Guo S, Li H
International journal of molecular sciences 2023 Jan 20;24(3)
International journal of molecular sciences 2023 Jan 20;24(3)
IDH2, a novel target of OGT, facilitates glucose uptake and cellular bioenergy production via NF-κB signaling to promote colorectal cancer progression.
He X, Wu N, Li R, Zhang H, Zhao Y, Nie Y, Wu J
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):145-164
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):145-164
The Degree of Hydrolysis and Peptide Profile Affect the Anti-Fatigue Activities of Whey Protein Hydrolysates in Promoting Energy Metabolism in Exercise Mice.
Zhao C, Gong Y, Zheng L, Zhao M
Journal of agricultural and food chemistry 2023 Feb 15;71(6):3010-3021
Journal of agricultural and food chemistry 2023 Feb 15;71(6):3010-3021
BMP4 participates in the pathogenesis of PCOS by regulating glucose metabolism and autophagy in granulosa cells under hyperandrogenic environment.
Gu R, Dai F, Xiang C, Chen J, Yang D, Tan W, Wang Z, Liu H, Cheng Y
The Journal of steroid biochemistry and molecular biology 2023 Dec;235:106410
The Journal of steroid biochemistry and molecular biology 2023 Dec;235:106410
Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation.
Yan SB, Liang H, Zhan P, Zheng H, Zhao QX, Zheng ZJ, Lu HX, Shang GK, Ji XP
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2623-2641
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2623-2641
Phenolic Constituents from Black Quinoa Alleviate Insulin Resistance in HepG2 Cells via Regulating IRS1/PI3K/Akt/GLUTs Signaling Pathways.
Cao M, Wang J, Jiang X, Sun Z, Zhao L, Chen G
Journal of agricultural and food chemistry 2023 Dec 6;71(48):18780-18791
Journal of agricultural and food chemistry 2023 Dec 6;71(48):18780-18791
Biochemical Toxicological Study of Insulin Overdose in Rats: A Forensic Perspective.
Bian C, He X, Wang Q, Zheng Z, Zhang Y, Xiong H, Li Y, Zhao M, Li J
Toxics 2023 Dec 23;12(1)
Toxics 2023 Dec 23;12(1)
Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload.
Qin X, Fu Y, Fan J, Liu B, Liu P, Zhang Y, Jiang T, Zheng Q
Journal of pineal research 2023 Apr;74(3):e12851
Journal of pineal research 2023 Apr;74(3):e12851
Isoginkgetin, a potential CDK6 inhibitor, suppresses SLC2A1/GLUT1 enhancer activity to induce AMPK-ULK1-mediated cytotoxic autophagy in hepatocellular carcinoma.
Yao J, Tang S, Shi C, Lin Y, Ge L, Chen Q, Ou B, Liu D, Miao Y, Xie Q, Tang X, Fei J, Yang G, Tian J, Zeng X
Autophagy 2023 Apr;19(4):1221-1238
Autophagy 2023 Apr;19(4):1221-1238
Intermittent fasting attenuates obesity-related atrial fibrillation via SIRT3-mediated insulin resistance mitigation.
Zhang Y, Gao F, Gong H, Fu Y, Liu B, Qin X, Zheng Q
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166638
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166638
Perturbated glucose metabolism augments epithelial cell proinflammatory function in chronic rhinosinusitis.
Chen CL, Ma J, Lu RY, Wang YT, Zhao JF, Kang YF, Hu JJ, Wang N, Song J, Zhong J, Chen C, Wang H, Liu Z
The Journal of allergy and clinical immunology 2023 Apr;151(4):991-1004.e20
The Journal of allergy and clinical immunology 2023 Apr;151(4):991-1004.e20
Alpha-Ketoglutarate Alleviates Neuronal Apoptosis Induced by Central Insulin Resistance through Inhibiting S6K1 Phosphorylation after Subarachnoid Hemorrhage.
Ding PF, Zhu Q, Sheng B, Yang H, Xu HJ, Tao T, Peng Z, Chen XX, Li XJ, Zhou Y, Zhang HS, Gao YY, Zhuang Z, Hang CH, Li W
Oxidative medicine and cellular longevity 2022;2022:9148257
Oxidative medicine and cellular longevity 2022;2022:9148257
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Zhang YL, Li PB, Han X, Zhang B, Li HH
Oxidative medicine and cellular longevity 2022;2022:6196173
Oxidative medicine and cellular longevity 2022;2022:6196173
Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells.
Lin L, Wang X, Zhao W, Chen Y
Genetics research 2022;2022:1500768
Genetics research 2022;2022:1500768
Hyperinsulinemia-induced microglial mitochondrial dynamic and metabolic alterations lead to neuroinflammation in vivo and in vitro.
Yang X, Xu Y, Gao W, Wang L, Zhao X, Liu G, Fan K, Liu S, Hao H, Qu S, Dong R, Ma X, Ma J
Frontiers in neuroscience 2022;16:1036872
Frontiers in neuroscience 2022;16:1036872
DPHB, a diarylheptane from Alpinia officinarum Hance, ameliorates insulin resistance: A network pharmacology and in vitro study.
Li X, Wen H, Zhang Y, Liu A, Zhang X, Fu M, Pan Y, Xu J, Zhang J
Frontiers in pharmacology 2022;13:956812
Frontiers in pharmacology 2022;13:956812
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
Ye Z, Ma J, Liu Y, Xu B, Dai X, Fu M, Tian T, Sui X, Mo F, Gao S, Zhao D, Zhang D
Frontiers in pharmacology 2022;13:950535
Frontiers in pharmacology 2022;13:950535
A Metabolism-Related Gene Landscape Predicts Prostate Cancer Recurrence and Treatment Response.
Zhou L, Fan R, Luo Y, Zhang C, Jia D, Wang R, Zeng Y, Ren M, Du K, Pan W, Yang J, Tian F, Gu C
Frontiers in immunology 2022;13:837991
Frontiers in immunology 2022;13:837991
Skeletal Muscle Dysfunction in Experimental Pulmonary Hypertension.
Kosmas K, Michael Z, Papathanasiou AE, Spyropoulos F, Adib E, Jasuja R, Christou H
International journal of molecular sciences 2022 Sep 18;23(18)
International journal of molecular sciences 2022 Sep 18;23(18)
A diarylheptanoid compound from Alpinia officinarum Hance ameliorates high glucose-induced insulin resistance by regulating PI3K/AKT-Nrf2-GSK3β signaling pathways in HepG2 cells.
Zhang XG, Liu AX, Zhang YX, Zhou MY, Li XY, Fu MH, Pan YP, Xu J, Zhang JQ
Journal of ethnopharmacology 2022 Sep 15;295:115397
Journal of ethnopharmacology 2022 Sep 15;295:115397
The influence of perinatal maternal exposure to dibutyl phthalate on glucolipid metabolism in adult female offspring.
Zhou K, Cheng R, Zhu M, Yang M, Shen X, Luo X, Ma L, Xu L, Zhang J
Obesity research & clinical practice 2022 Nov-Dec;16(6):500-506
Obesity research & clinical practice 2022 Nov-Dec;16(6):500-506
Dietary N(ε)-(carboxymethyl) lysine affects cardiac glucose metabolism and myocardial remodeling in mice.
Wang ZQ, Sun Z
World journal of diabetes 2022 Nov 15;13(11):972-985
World journal of diabetes 2022 Nov 15;13(11):972-985
Exercise improves high-fat diet-induced metabolic disorder by promoting HDAC5 degradation through the ubiquitin-proteasome system in skeletal muscle.
Huang S, Zheng X, Zhang X, Jin Z, Liu S, Fu L, Niu Y
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Nov 1;47(11):1062-1074
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Nov 1;47(11):1062-1074
Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.
Dai HB, Wang HY, Wang FZ, Qian P, Gao Q, Zhou H, Zhou YB
Acta diabetologica 2022 May;59(5):661-673
Acta diabetologica 2022 May;59(5):661-673
Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway.
Ni J, Liu Z, Jiang M, Li L, Deng J, Wang X, Su J, Zhu Y, He F, Mao J, Gao X, Fan G
Journal of ginseng research 2022 Mar;46(2):235-247
Journal of ginseng research 2022 Mar;46(2):235-247
Elucidation of the interaction effect between dietary fiber and bound polyphenol components on the anti-hyperglycemic activity of tea residue dietary fiber.
Huang H, Chen J, Hu X, Chen Y, Xie J, Ao T, Wang H, Xie J, Yu Q
Food & function 2022 Mar 7;13(5):2710-2728
Food & function 2022 Mar 7;13(5):2710-2728
Psoralen Suppresses Lipid Deposition by Alleviating Insulin Resistance and Promoting Autophagy in Oleate-Induced L02 Cells.
Wang Y, Wang Y, Li F, Zou J, Li X, Xu M, Yu D, Ma Y, Huang W, Sun X, Zhang Y
Cells 2022 Mar 22;11(7)
Cells 2022 Mar 22;11(7)
Remodeling on adipocytic physiology of organophosphorus esters in mature adipocytes.
Liu Y, Le Y, Xu M, Wang W, Chen H, Zhang Q, Wang C
Environmental pollution (Barking, Essex : 1987) 2022 Jul 15;305:119287
Environmental pollution (Barking, Essex : 1987) 2022 Jul 15;305:119287
A novel regulatory mechanism of geniposide for improving glucose homeostasis mediated by circulating RBP4.
Liu J, Song C, Nie C, Sun Y, Wang Y, Xue L, Fan M, Qian H, Wang L, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153862
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153862
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.
Wang P, Li CG, Zhou X, Ding S
Clinical and experimental pharmacology & physiology 2022 Feb;49(2):302-310
Clinical and experimental pharmacology & physiology 2022 Feb;49(2):302-310
Effects of distinct n-6 to n-3 polyunsaturated fatty acid ratios on insulin resistant and AD-like phenotypes in high-fat diets-fed APP/PS1 mice.
Ma X, Guo Y, Xu J, Wang X, Dong S, Gao Y, Van Halm-Lutterodt N, Yuan L
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt B):112207
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt B):112207
Fermented noni (Morinda citrifolia L.) fruit juice improved oxidative stress and insulin resistance under the synergistic effect of Nrf2/ARE pathway and gut flora in db/db mice and HepG2 cells.
Zhang X, Zhang B, Li L, Li X, Zhang J, Chen G
Food & function 2022 Aug 1;13(15):8254-8273
Food & function 2022 Aug 1;13(15):8254-8273
α-Pyrones with glucose uptake-stimulatory activity from the twigs of Cryptocarya wrayi.
Wang XN, Kuang XD, Wang Y, Sun P, He XR, Peng YA, Liu LH, Gu JL, Gan LS, Wang XN, Shu JC, Zhou ZW
Fitoterapia 2022 Apr;158:105144
Fitoterapia 2022 Apr;158:105144
Mechanism of Electroacupuncture Regulating IRS-1 Phosphorylation in Skeletal Muscle to Improve Insulin Sensitivity.
Song S, Li R, Cao B, Zhang J, Kim Y, Kim B, Yu X
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8631475
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8631475
Activation of Hippocampal IR/IRS-1 Signaling Contributes to the Treatment with Zuogui Jiangtang Jieyu Decoction on the Diabetes-Related Depression.
Yang H, Ling J, Meng P, Liu J, Lin X, Li W, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6688723
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6688723
Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1α Signaling Pathway.
Bai Y, Zuo J, Fang X, Ma R, Tian T, Mo F, Mu Q, Zhang Y, Yu N, Bao X, Zhang D, Gao S, Zhao D
Oxidative medicine and cellular longevity 2021;2021:5566053
Oxidative medicine and cellular longevity 2021;2021:5566053
Total Sesquiterpene Glycosides from Loquat Leaves Ameliorate HFD-Induced Insulin Resistance by Modulating IRS-1/GLUT4, TRPV1, and SIRT6/Nrf2 Signaling Pathways.
Wu R, Jian T, Ding X, Lv H, Meng X, Ren B, Li J, Chen J, Li W
Oxidative medicine and cellular longevity 2021;2021:4706410
Oxidative medicine and cellular longevity 2021;2021:4706410
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
Sun N, Meng F, Zhao J, Li X, Li R, Han J, Chen X, Cheng W, Yang X, Kou Y, Zheng K, Yang J, Ikezoe T
International journal of biological sciences 2021;17(5):1302-1314
International journal of biological sciences 2021;17(5):1302-1314
Mechanism of Mongolian Medicine Eerdun Wurile in Improving Postoperative Cognitive Dysfunction Through Activation of the PI3K Signaling Pathway.
Lv Z, Che L, Du Y, Yu J, Su E, Liu H, Chen D
Frontiers in neuroscience 2021;15:769759
Frontiers in neuroscience 2021;15:769759
DPHC From Alpinia officinarum Ameliorates Oxidative Stress and Insulin Resistance via Activation of Nrf2/ARE Pathway in db/db Mice and High Glucose-Treated HepG2 Cells.
Zhang X, Zhang Y, Zhou M, Xie Y, Dong X, Bai F, Zhang J
Frontiers in pharmacology 2021;12:792977
Frontiers in pharmacology 2021;12:792977
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
Zhang Y, Fu Y, Jiang T, Liu B, Sun H, Zhang Y, Fan B, Li X, Qin X, Zheng Q
Frontiers in pharmacology 2021;12:771940
Frontiers in pharmacology 2021;12:771940
DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model.
Tao J, Yu XL, Yuan YJ, Shen X, Liu J, Gu PP, Wang Z, Ma YT, Li GQ
Frontiers in endocrinology 2021;12:723623
Frontiers in endocrinology 2021;12:723623
Effects of endurance training on the expression of host proteins involved in SARS-CoV-2 cell entry in C57BL/6J mouse.
Tamura Y, Jee E, Kouzaki K, Kotani T, Nakazato K
Physiological reports 2021 Sep;9(17):e15014
Physiological reports 2021 Sep;9(17):e15014
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters.
Jiang MJ, Li L, Huang WF, Su J, Li YH, Qu XS, Fan LL
Journal of natural medicines 2021 Sep;75(4):884-892
Journal of natural medicines 2021 Sep;75(4):884-892
Magnesium lithospermate B supplementation improved prenatal Bisphenol A exposure-induced metabolic abnormalities in male offspring.
Huang WC, Liao KY, Hsieh SK, Pan PH, Kuan YH, Liao SL, Chen CJ, Chen WY
Environmental toxicology 2021 Sep;36(9):1932-1943
Environmental toxicology 2021 Sep;36(9):1932-1943
Gliquidone ameliorates hepatic insulin resistance in streptozotocin-induced diabetic Sur1(-/-) rats.
Zhang R, Zhou X, Sheng Q, Zhang Q, Xie T, Xu C, Zou Z, Dong J, Liao L
European journal of pharmacology 2021 Sep 5;906:174221
European journal of pharmacology 2021 Sep 5;906:174221
Integrated analysis of long non-coding RNAs and mRNAs associated with malignant transformation of gastrointestinal stromal tumors.
Yin X, Yin Y, Dai L, Shen C, Chen N, Li J, Cai Z, Jiang Z, Wang J, Zhao Z, Chen X, Deng H, Zhang B
Cell death & disease 2021 Jul 3;12(7):669
Cell death & disease 2021 Jul 3;12(7):669
Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export.
Wang K, Huang W, Chen R, Lin P, Zhang T, Ni YF, Li H, Wu J, Sun XX, Geng JJ, Zhu YM, Nan G, Zhang W, Chen X, Zhu P, Bian H, Chen ZN
Cell metabolism 2021 Jan 5;33(1):160-173.e6
Cell metabolism 2021 Jan 5;33(1):160-173.e6
ERα down-regulates carbohydrate responsive element binding protein and decreases aerobic glycolysis in liver cancer cells.
Lu Y, Tian N, Hu L, Meng J, Feng M, Zhu Y, Zhang P, Li M, Liu Q, Tong L, Tong X, Li Y, Wu L
Journal of cellular and molecular medicine 2021 Apr;25(7):3427-3436
Journal of cellular and molecular medicine 2021 Apr;25(7):3427-3436
AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.
Chen M, Ji C, Yang Q, Gao S, Peng Y, Li Z, Gao X, Li Y, Jiang N, Zhang Y, Bian X, Chen C, Zhang K, Sanchis D, Yan F, Ye J
Clinical science (London, England : 1979) 2020 Sep 18;134(17):2381-2398
Clinical science (London, England : 1979) 2020 Sep 18;134(17):2381-2398
High-fat diet induced discrepant peripheral and central nervous systems insulin resistance in APPswe/PS1dE9 and wild-type C57BL/6J mice.
Guo Y, Ma X, Li P, Dong S, Huang X, Ren X, Yuan L
Aging 2020 Dec 3;13(1):1236-1250
Aging 2020 Dec 3;13(1):1236-1250
Metformin ameliorates skeletal muscle atrophy in Grx1 KO mice by regulating intramuscular lipid accumulation and glucose utilization.
Yang Y, Liao Z, Xiao Q
Biochemical and biophysical research communications 2020 Dec 17;533(4):1226-1232
Biochemical and biophysical research communications 2020 Dec 17;533(4):1226-1232
Frequent and mild scrotal heat stress in mice epigenetically alters glucose metabolism in the male offspring.
Wan X, He X, Liu Q, Wang X, Ding X, Li H
American journal of physiology. Endocrinology and metabolism 2020 Aug 1;319(2):E291-E304
American journal of physiology. Endocrinology and metabolism 2020 Aug 1;319(2):E291-E304
Chlorogenic Acid Stimulates the Thermogenesis of Brown Adipocytes by Promoting the Uptake of Glucose and the Function of Mitochondria.
Han X, Zhang Y, Guo J, You Y, Zhan J, Huang W
Journal of food science 2019 Dec;84(12):3815-3824
Journal of food science 2019 Dec;84(12):3815-3824
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Wang S, Li J, Xie J, Liu F, Duan Y, Wu Y, Huang S, He X, Wang Z, Wu X
Oncogene 2018 Jul;37(30):4164-4180
Oncogene 2018 Jul;37(30):4164-4180
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