PAB11266

antibody from Abnova Corporation

Targeting: RBL2 p130, Rb2

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB11266

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB11266, RRID:AB_1712702

Product name

RBL2 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of RBL2.

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

A small molecule based on the pRb2/p130 spacer domain leads to inhibition of cdk2 activity, cell cycle arrest and tumor growth reduction in vivo.

Bagella L, Sun A, Tonini T, Abbadessa G, Cottone G, Paggi MG, De Luca A, Claudio PP, Giordano A
Oncogene 2007 Mar 22;26(13):1829-39

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From G0 to S phase: a view of the roles played by the retinoblastoma (Rb) family members in the Rb-E2F pathway.

Sun A, Bagella L, Tutton S, Romano G, Giordano A
Journal of cellular biochemistry 2007 Dec 15;102(6):1400-4

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Frequent loss of pRb2/p130 in human ovarian carcinoma.

D'Andrilli G, Masciullo V, Bagella L, Tonini T, Minimo C, Zannoni GF, Giuntoli RL 2nd, Carlson JA Jr, Soprano DR, Soprano KJ, Scambia G, Giordano A
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 May 1;10(9):3098-103

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot using RBL2 polyclonal antibody (Cat # PAB11266) shows detection of endogenous RBL2 protein in whole LNCaP cell extracts.The band at ~130 KDa (arrowhead).The primary antibody was diluted 1 : 500.Personal communication, Ang Sun, Sbarro Institute for Cancer Research and Molecular Medicine, Temple University, Philadelphia, PA.