ABIN116943

antibody from antibodies-online

Targeting: RBL2 p130, Rb2

Western blot (Recommended by provider)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

ABIN116943

Provider

antibodies-online

Product name

anti-Retinoblastoma-Like 2 (p130) (RBL2) antibody

Antibody type

Polyclonal

Antigen

Rb2 (p130) peptide corresponding to the C-terminus of the Human protein conjugated toKeyhole Limpet Hemocyanin (KLH). Genename: RBL2

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

0.1 mL

Concentration

85 mg/ml (by Refractometry)

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Dilute only prior to immediate use. Avoid repeated freezing and thawing. Shelf life: One year from despatch.

References

Submitted references

pRb2/p130 promotes radiation-induced cell death in the glioblastoma cell line HJC12 by p73 upregulation and Bcl-2 downregulation.

Pucci B, Claudio PP, Masciullo V, Bellincampi L, Terrinoni A, Khalili K, Melino G, Giordano A
Oncogene 2002 Aug 29;21(38):5897-905

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p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107.

Claudio PP, Howard CM, Baldi A, De Luca A, Fu Y, Condorelli G, Sun Y, Colburn N, Calabretta B, Giordano A
Cancer research 1994 Nov 1;54(21):5556-60

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Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain.

Mayol X, Graña X, Baldi A, Sang N, Hu Q, Giordano A
Oncogene 1993 Sep;8(9):2561-6

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The retinoblastoma-related gene, RB2, maps to human chromosome 16q12 and rat chromosome 19.

Yeung RS, Bell DW, Testa JR, Mayol X, Baldi A, Graña X, Klinga-Levan K, Knudson AG, Giordano A
Oncogene 1993 Dec;8(12):3465-8