M02445

antibody from Boster Biological Technology
Targeting: PABPN1 OPMD, PAB2, PABP2
Provider product page for M02445
Western blot
Immunocytochemistry
Immunoprecipitation

Antibody data

Product number
M02445 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-PABPN1 Rabbit Monoclonal Antibody
Antibody type
Monoclonal
Description
Monoclonal antibody for PABPN1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IP, IF, IHC, ICC, WB. Reactive species: Human, Mouse PABPN1 information: Molecular Weight: 32749 MW; Subcellular Localization: Nucleus . Cytoplasm . Nucleus speckle . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles between the nucleus and the cytoplasm but predominantly found in the nucleus (PubMed:10688363). Its nuclear import may involve the nucleocytoplasmic transport receptor transportin and a RAN-GTP- sensitive import mechanism (By similarity). Is exported to the cytoplasm by a carrier-mediated pathway that is independent of mRNA traffic. Colocalizes with SKIP and poly(A) RNA in nuclear speckles (By similarity). Intranuclear filamentous inclusions or "aggregates" are detected in the myocytes of patients; these inclusions contain PABPN1, ubiquitin, subunits of the proteasome and poly(A) RNA; Tissue Specificity: Ubiquitous.
Reactivity
Human, Mouse
Host
Rabbit
Antibody clone number
AAHI-16
Vial size
100ug/vial
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage
At -20°C for one year. Avoid repeated freezing and thawing.
PABPN1 protein structure - M02445 shown in red.